Results 41 to 50 of about 265 (236)
On Newton's method using recurrent functions under hypotheses up to the second Fréchet derivative
We provide semilocal result for the convergence of Newton method to a locally unique solution of an equation in a Banach space setting using hypotheses up to the second Fréchet-derivatives and our new idea of recurrent functions.
Ioannis K. Argyros, Saïd Hilout
doaj +2 more sources
A convergence analysis of an iterative algorithm of order \(1.839\ldots\) under weak assumptions
We provide new and weaker sufficient local and semilocal conditions for the convergence of a certain iterative method of order 1.839\(\ldots\) to a solution of an equation in a Banach space.
Ioannis K. Argyros
doaj +2 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
A major component approach to presenting consensus sequences. [PDF]
Abstract MOTIVATION: Summarizing and displaying the information contained in a set of aligned sequences is an important aid to identifying patterns within the sequences. A variety of forms of consensus sequences have been used previously to provide this information.
Smith, David Keith, Xue, Hong
openaire +3 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Majorizing sequences for Newton’s method from initial value problems
The most restrictive condition used by Kantorovich for proving the semilocal convergence of Newton's method in Banach spaces is relaxed in this paper, providing we can guarantee the semilocal convergence in situations that Kantorovich cannot. To achieve this, we use Kantorovich's technique based on majorizing sequences, but our majorizing sequences are
Ezquerro, null +2 more
openaire +4 more sources
Convergence Conditions for the Secant Method
We provide new sufficient convergence conditions for the convergence of the Secant method to a locally unique solution of a nonlinear equation in a Banach space.
Ioannis K Argyros +1 more
doaj
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source

