Results 51 to 60 of about 293 (242)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Global majority consensus by local majority polling on graphs of a given degree sequence

open access: yesDiscrete Applied Mathematics, 2015
Suppose in a graph $G$ vertices can be either red or blue. Let $k$ be odd. At each time step, each vertex $v$ in $G$ polls $k$ random neighbours and takes the majority colour. If it doesn't have $k$ neighbours, it simply polls all of them, or all less one if the degree of $v$ is even.
Mohammed Amin Abdullah 0001, Moez Draief
openaire   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

An improved error analysis for Newton-like methods under generalized conditions

open access: yes, 2003
We introduce new semilocal convergence theorems for Newton-like methods in a Banach space setting. Using new and very general conditions we provide different sufficient convergence conditions than before.
Argyros, Ioannis K
core   +1 more source

Designing radar transmit sequences satisfying simultaneous temporal integrated sidelobe level and spectral stopband constraints

open access: yes, 2020
Due to their nice properties, unimodular sequences possessing low autocorrelation sidelobes have already been employed as transmit waveforms in numerous radar systems.
AKAY, OLCAY, Biskin, Osman Tayfun
core   +1 more source

The Papillomavirus Episteme: a major update to the papillomavirus sequence database [PDF]

open access: yesNucleic Acids Research, 2016
The Papillomavirus Episteme (PaVE) is a database of curated papillomavirus genomic sequences, accompanied by web-based sequence analysis tools. This update describes the addition of major new features. The papillomavirus genomes within PaVE have been further annotated, and now includes the major spliced mRNA transcripts. Viral genes and transcripts can
Koenraad Van Doorslaer   +9 more
openaire   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

On the Semi-Local Convergence of a Noor–Waseem-like Method for Nonlinear Equations

open access: yes, 2022
The significant feature of this paper is that the semi-local convergence of high order methods for solving nonlinear equations defined on abstract spaces has not been studied extensively as done for the local convergence by a plethora of authors which is
Michael I. Argyros   +3 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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