Results 141 to 150 of about 237,599 (252)
Nonsteroidal Anti-inflammatory Drugs (NSAIDs) and Collision Sports: The Need for Further Education in Rugby. [PDF]
Papadimos TJ +3 more
europepmc +1 more source
MAKE-BELIEVE PLAY: THE ABILITY TO DISTINGUISH BETWEEN REALITY AND IMAGINATION
Leslie (1988b) argues that lhe ability to pretend and tounderstand pretense in others, requires mastery of the same logicalstructures required to understand mental states. Early pretend play isactually a primitive manifestation of the child's theory of mind and emergesusually between 18 and 24 months. The aim of this study was to analyseamong orphanage
openaire +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
The last low whispers revisited: a reply to Sulmasy on palliative sedation. [PDF]
Lee H.
europepmc +1 more source
Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Publishing with purpose: Bringing lived experiences into journal development. [PDF]
Montague-Cardoso K +9 more
europepmc +1 more source
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Attitudes, Norms, and Control: What Is Shaping Fijian Children's Physical Activity and Screen Time Behaviours? [PDF]
Ryan ST +4 more
europepmc +1 more source

