Results 51 to 60 of about 2,153 (178)

Morbidité et mortalité hospitalière des maladies cardiovasculaires en milieu tropical: exemple d'un centre hospitalier à Lomé (Togo)

open access: yesThe Pan African Medical Journal, 2014
INTRODUCTION: Les maladies cardiovasculaires (MCV) occupent une place importante dans la mortalité en Afrique, situation inquiétante traduisant une transition épidémiologique rapide.
Findibe Damorou   +10 more
doaj   +1 more source

Strengthening health‐focused climate adaptation in Canada: Barriers and interventions

open access: yesCanadian Geographer / Le géographe canadien, Volume 68, Issue 4, Page 445-450, Winter / hiver 2024.
Abstract Climate change poses a dire threat to human health. Within Canada, extreme heat events are contributing to cardiovascular disease, poor air quality is causing respiratory distress, and changing precipitation patterns are resulting in the spread of vector‐borne illness.
Desiree Rose, S. Jeff Birchall
wiley   +1 more source

Triglycéridémie postprandiale, insulinémie, leptinémie et distribution des apolipoprotéines CIII entre TGRL et HDL chez l’homme normolipidémique

open access: yesOléagineux, Corps gras, Lipides, 2002
Notre article, publié en 1998 dans OCL sur la « Leptine, épuration et utilisation postprandiales des lipides chez l’homme », faisait état pour la première fois d’un lien entre cette hormone produite par le tissu adipeux et le risque de maladies ...
Le Roy Brigitte   +6 more
doaj   +1 more source

Integrated spatial and multimodal single‐cell transcriptomics reveal patient‐dependent cell heterogeneity in splenic marginal zone lymphoma

open access: yesThe Journal of Pathology, Volume 263, Issue 4-5, Page 442-453, August 2024.
Abstract Biological hallmarks of splenic marginal zone lymphoma (SMZL) remain poorly described. Herein, we performed in‐depth SMZL characterization through multimodal single‐cell analyses of paired blood/spleen samples. The 3’‐single‐cell RNA‐sequencing, Cellular Indexing of Transcriptomes and Epitopes by sequencing, and 5’‐V(D)J single‐cell RNA ...
Juan Pablo Cerapio   +11 more
wiley   +1 more source

Acides gras oméga 3 et maladies cardiovasculaires : approches épidémiologiques

open access: yesOléagineux, Corps gras, Lipides, 2004
La prise alimentaire d’acides gras oméga 3 a de nombreuses conséquences biologiques en particulier dans les domaines intéressant le risque cardiovasculaire (thrombose, métabolisme lipidique, inflammation). A partir de l’énorme littérature épidémiologique
Ducimetiere Pierre
doaj   +1 more source

The E3 ubiquitin ligase TRIP12 is required for pancreatic acinar cell plasticity and pancreatic carcinogenesis

open access: yesThe Journal of Pathology, Volume 263, Issue 4-5, Page 466-481, August 2024.
Abstract The E3 ubiquitin ligase thyroid hormone receptor interacting protein 12 (TRIP12) has been implicated in pancreatic adenocarcinoma (PDAC) through its role in mediating the degradation of pancreas transcription factor 1a (PTF1a). PTF1a is a transcription factor essential for the acinar differentiation state that is notably diminished during the ...
Manon Brunet   +17 more
wiley   +1 more source

Longitudinal Evaluation of Bronchial Changes in Cystic Fibrosis Patients Undergoing Elexacaftor/Tezacaftor/Ivacaftor Therapy Using Lung MRI With Ultrashort Echo‐Times

open access: yesJournal of Magnetic Resonance Imaging, Volume 60, Issue 1, Page 116-124, July 2024.
Background Lung magnetic resonance imaging (MRI) with ultrashort echo‐times (UTE‐MRI) allows high‐resolution and radiation‐free imaging of the lung structure in cystic fibrosis (CF). In addition, the combination of elexacaftor/tezacaftor/ivacaftor (ETI) has improved CF clinical outcomes such as need for hospitalization.
Mathieu David   +7 more
wiley   +1 more source

Assessment of fatigue in adult patients with sickle cell disease: Use of the functional assessment of chronic illness therapy—Fatigue (FACIT‐fatigue) questionnaire

open access: yesBritish Journal of Haematology, Volume 205, Issue 1, Page 335-342, July 2024.
Fatigue is a major symptom of adult patients with sickle cell disease (SCD). To assess the burden of fatigue in our cohort, 102 adult patients with SCD at steady‐state filled the FACIT‐Fatigue questionnaire (ranging from 0 (worst imaginable fatigue) to 52 (no fatigue)).
Geoffrey Cheminet   +10 more
wiley   +1 more source

Molecular mechanisms of perilipin protein function in lipid droplet metabolism

open access: yesFEBS Letters, Volume 598, Issue 10, Page 1170-1198, May 2024.
Lipid droplets (LDs) are important for the storage of energy and lipid components. The perilipin family in mammals includes five proteins (PLIN1 to PLIN5), all of which are abundant on the surface of LDs in different tissues and play a role in LD stability and degradation by lipases.
Elena Griseti   +7 more
wiley   +1 more source

Commentaire - Changements climatiques, santé et avantages connexes des espaces verts

open access: yesPromotion de la santé et prévention des maladies chroniques au Canada, 2019
Nous avons examiné deux des défis actuels de l’humanité, soit les changements climatiques et les maladies chroniques, en fonction des avantages connexes que les espaces verts procurent à la santé humaine et à l’environnement.
Marianne Kingsley, EcoHealth Ontario
doaj   +1 more source

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