Results 41 to 50 of about 2,153 (178)

Incidence and Predictors of Heart Failure in Patients With Atrial Fibrillation

CJC Open, 2021
Background: Heart failure (HF) is a frequent cause of hospitalization and death in patients with atrial fibrillation (AF). Identifying AF patients at risk of HF hospitalization could help select individuals for intensive follow-up and treatment. Methods:
Philipp Krisai, MD, Linda S.B. Johnson, MD, PhD, Giorgio Moschovitis, MD, MSc, Alexander Benz, MD, MSc, Chinthanie Ramasundarahettige, MSc, William F. McIntyre, MD, Jorge A. Wong, MD, MPH, David Conen, MD, MPH, Christian Sticherling, MD, Stuart J. Connolly, MD, Jeff S. Healey, MD, MSc   +10 more
doaj   +1 more source

Acute myocarditis according to age: Presentation, management and early outcomes

ESC Heart Failure, Volume 12, Issue 4, Page 2932-2945, August 2025.
MIS, multisystem inflammatory syndrome; MRE, myocarditis‐related events (within 30 days included all‐cause death, cardiogenic shock, cardiac arrest, ventricular arrhythmias or complete AV block). Abstract Aims Acute myocarditis (AM) is a rare but severe disease affecting patients of all ages. Large multicentric studies comparing children and adults are
Clément Karsenty, Paul Vignaud, Clara Brusq, Pamela Moceri, Pascal Lim, Edouard Gerbaud, Olivier Lairez, Coline Lelarge, Caroline Ovaert, Claire Bouleti, Oscar Werner, Vanina Bongard, Thibaud Genet, Laurent Bonnemains, Christophe Tron, Elise Barre, Margaux Boddaert, Jacques Mansourati, Chérine Benzouid, François Roubille, Hadi Khachab, Sabrina Uhry, Ariel Cohen, Benoit Lattuca, Sylvie Di Filippo, Clément Delmas   +25 more
wiley   +1 more source

Reduced Capacity of High‐Density Lipoprotein to Acquire Free Cholesterol From Triglyceride‐Rich Lipoproteins Is Associated With Elevated Postprandial Hypertriglyceridemia in Healthy Men

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The capacity of high‐density lipoprotein cholesterol (HDL) to acquire free cholesterol (FC) from triglyceride‐rich lipoproteins during lipoprotein lipase–dependent lipolysis in a process of reverse remnant cholesterol transport, has been ...
Sophie Galier, Maryam Darabi, Feng Ma, Clément Materne, Isabelle Guillas, Wilfried Le Goff, Anatol Kontush, Maryse Guerin   +7 more
doaj   +1 more source

Human colonic organoids for understanding early events of familial adenomatous polyposis pathogenesis

The Journal of Pathology, Volume 265, Issue 1, Page 26-40, January 2025.
Abstract Patients with familial adenomatous polyposis (FAP) harbor mutations in the APC gene and will develop adenoma and early colorectal cancer. There is no validated treatment, and animal models are not sufficient to study FAP. Our aim was to investigate the early events associated with FAP using the intestinal organoid model in a single‐center ...
Nolwenn Laborde, Alexandre Barusseaud, Muriel Quaranta, Corinne Rolland, Amélie Arrouy, Delphine Bonnet, Sylvain Kirzin, Nuria Sola‐Tapias, Dimitri Hamel, Karl Barange, Jean‐Pierre Duffas, Marie‐Pierre Gratacap, Julie Guillermet‐Guibert, Anne Breton, Nathalie Vergnolle, Laurent Alric, Audrey Ferrand, Frédérick Barreau, Claire Racaud‐Sultan, Emmanuel Mas   +19 more
wiley   +1 more source

Cellular Senescence in Renal and Urinary Tract Disorders

Cells, 2020
Cellular senescence is a state of cell cycle arrest induced by repetitive cell mitoses or different stresses, which is implicated in various physiological or pathological processes.
Yohan Santin, Philippe Lluel, Pascal Rischmann, Xavier Gamé, Jeanne Mialet-Perez, Angelo Parini   +5 more
doaj   +1 more source

Penetration of linezolid and tedizolid in cerebrospinal fluid of mouse and impact of blood–brain barrier disruption

Clinical and Translational Science, Volume 18, Issue 1, January 2025.
Abstract Penetration of antimicrobial treatments into the cerebrospinal fluid is essential to successfully treat infections of the central nervous system. This penetration is hindered by different barriers, including the blood–brain barrier, which is the most impermeable.
Marin Lahouati, Mélanie Oudart, Philippe Alzieu, Candice Chapouly, Antoine Petitcollin, Fabien Xuereb   +5 more
wiley   +1 more source

Blood shear stress during the cardiac cycle and endothelial cell orientation and polarity in the carotid artery of male and female mice

Frontiers in Physiology
Introduction: Blood flow produces fluid shear stress (SS), a frictional force parallel to the blood flow, on the endothelial cell (EC) layer of the lumen of the vessels. ECs themselves are sensitive to this frictional force in terms of directionality and
Nabil Nicolas, Alexandre de Tilly, Etienne Roux   +2 more
doaj   +1 more source

Estrogen receptor subcellular localization and cardiometabolism

Molecular Metabolism, 2018
Background: In addition to their crucial role in reproduction, estrogens are key regulators of energy and glucose homeostasis and they also exert several cardiovascular protective effects. These beneficial actions are mainly mediated by estrogen receptor
Pierre Gourdy, Maeva Guillaume, Coralie Fontaine, Marine Adlanmerini, Alexandra Montagner, Henrik Laurell, Françoise Lenfant, Jean-François Arnal   +7 more
doaj   +1 more source

Etiologic Determinants and Characteristics of Diabetes in Haitian Youth (EDDHY Study)

Pediatric Diabetes, Volume 2025, Issue 1, 2025.
Aims: Published information on youth‐onset diabetes in Haiti is scarce, with limited data available on diabetes autoimmunity and genetic susceptibility to the disease. We determined the anthropometric, metabolic, and immunological characteristics and human leukocyte antigen (HLA)‐associated risks in patients with youth‐onset diabetes.
Eddy Jean-Baptiste, Philippe Larco, Julia E. Von Oettingen, Janelle A. Noble, Steven J. Mack, Ningyi Song, Harper R. N. Martin, Erik Rozemuller, Mark A. Atkinson, Denira Govender, Nancy Charles Larco, Graham D. Ogle, Andrea Scaramuzza   +12 more
wiley   +1 more source

Les Maladies Cardiovasculaires Chez les Patients en Hémodialyse Chronique à Bouaké

Health Research in Africa
RÉSUMÉ Introduction. L’hémodialyse chronique (HDC) occupe une place importante dans la prise en charge des patients en insuffisance rénale chronique terminale (IRCT), car elle prolonge la durée et améliore la qualité de vie.
Manzan E A Wognin, Hubert K Yao, Weu M Tia, Weu M Tia, Sébastienne A Yao, Christ Reine Marie Koffi, Monlet C Guei, Loa Ambroise Gnaba, Kehi J Kpan, Abdoul Y Gonan, Bourhaïma O   +10 more
doaj   +1 more source