Results 31 to 40 of about 2,205 (173)

Exercise Capacity, Endothelial Function, Muscle Mass, and Strength in Pediatric Patients With Fontan Circulation

CJC Pediatric &Congenital Heart Disease, Volume 5, Issue 3, Page 119-128, June 2026.
Abstract Background Fontan circulation carries high morbidity and mortality, driven in part by impaired exercise capacity, muscle deficits, and endothelial dysfunction. In a pediatric cohort with Fontan circulation, we examined associations between exercise capacity, endothelial function, and muscle parameters before enrollment in a randomized exercise
Mavis C. Lui, Latha Palaniappan, Mary B. Leonard, Jin Long, Joseph Dehoney, John P. Cooke, Inger Olson, Tulsi R. Damase, Sharon Chen, Jonathan Myers, Daniel Bernstein, Seda Tierney   +11 more
wiley   +1 more source

Platelet Versus Megakaryocyte: Who Is the Real Bandleader of Thromboinflammation in Sepsis?

Cells, 2022
Platelets are mainly known for their key role in hemostasis and thrombosis. However, studies over the last two decades have shown their strong implication in mechanisms associated with inflammation, thrombosis, and the immune system in various neoplastic,
Cédric Garcia, Baptiste Compagnon, Michaël Poëtte, Marie-Pierre Gratacap, François-Xavier Lapébie, Sophie Voisin, Vincent Minville, Bernard Payrastre, Fanny Vardon-Bounes, Agnès Ribes   +9 more
doaj   +1 more source

Comparison of Labscan 200 and FlexMap 3D Luminex for Anti‐HLA Antibodies Monitoring

HLA, Volume 107, Issue 5, May 2026.
ABSTRACT The new Luminex model FlexMap 3D is progressively replacing the previous Luminex generation in HLA laboratories for the detection and identification of anti‐HLA antibodies. FlexMap 3D Luminex promises a higher degree of sensitivity, which may lead to greater mean fluorescence intensities, depending on the anti‐HLA beads kit supplier.
J. Milhès, L. Duclercq, S. Blavy, A. Del Bello, N. Kamar, C. Bouthemy, N. Congy‐Jolivet   +6 more
wiley   +1 more source

G protein stoichiometry dictates biased agonism through distinct receptor-G protein partitioning

Scientific Reports, 2017
Biased agonism at G protein coupled receptors emerges as an opportunity for development of drugs with enhanced benefit/risk balance making biased ligand identification a priority.
Lauriane Onfroy, Ségolène Galandrin, Stéphanie M. Pontier, Marie-Hélène Seguelas, Du N’Guyen, Jean-Michel Sénard, Céline Galés   +6 more
doaj   +1 more source

Classical and Counter-Regulatory Renin–Angiotensin System: Potential Key Roles in COVID-19 Pathophysiology

CJC Open, 2021
In the current COVID-19 pandemic, severe acute respiratory syndrome coronavirus 2 uses angiotensin-converting enzyme-2 (ACE-2) receptors for cell entry, leading to ACE-2 dysfunction and downregulation, which disturb the balance between the classical and ...
Moudhi Almutlaq, MSc, Abir Abdullah Alamro, PhD, Fayhan Alroqi, MD, Tlili Barhoumi, PhD   +3 more
doaj   +1 more source

Mapping Intestinal Paracellular Perm Eability in Mice: Regional and Cellular Variability Under Physiological and Stimulated Conditions

FASEB BioAdvances, Volume 8, Issue 3, March 2026.
This study analyzed the paracellular permeability of the intestines of healthy mice at a basal level. A new detection method involving tissue incubation for 5 min with luminal fluorescent dyes, such as FM1‐43FX (FM), which bind to accessible plasma (or external) cell membranes, was developed.
Mathilde Miquel, Kadirey Verwaerde, Anissa Edir‐Kibri, Mikael Albin, Florence Blas‐Y‐Estrada, Audrey Samper, Elodie Rousseau‐Bacquie, Hervé Robert, Hélène Eutamène, Vassilia Théodorou, Christine Coméra   +10 more
wiley   +1 more source

Le lien entre l’alimentation et les maladies cardiovasculaires

One Health & Risk Management, 2023
INTRODUCTION Les maladies cardiovasculaires (MCV) sont la première cause de mortalité avec 17,9 millions de morts, suivi des cancers (9 millions) et des maladies respiratoires (3,9 millions) qui résultent d’une association de facteurs génétiques ...
Ana-Maria ZAVTONI, Cristina DUMITRAS
doaj  

GHSR agonism increases blood glucose but delays food intake in GHSR hyperresponsive rats

Journal of Neuroendocrinology, Volume 38, Issue 2, February 2026.
GHSR agonism increases blood glucose, inhibits locomotor activity and delays food intake in GHSR hyperresponsive rats. Abstract Severe calorie restriction in mouse models has highlighted the crucial role of the ghrelin system in maintaining glycemia and promoting survival.
Philippe Zizzari, Olalla Ramírez‐Penas, Véronique Pons, Matilda Oujezdska, Ange‐Louis Sammarcelli, Thomas Saint‐Yves, Inès Chevallier‐Chantepie, Lucile Baussart, Vanessa Nhan, Adèle Phalip, Céline Gales, Daniela Cota, Florence Noble, Jacques Pantel   +13 more
wiley   +1 more source

Incidence and Predictors of Heart Failure in Patients With Atrial Fibrillation

CJC Open, 2021
Background: Heart failure (HF) is a frequent cause of hospitalization and death in patients with atrial fibrillation (AF). Identifying AF patients at risk of HF hospitalization could help select individuals for intensive follow-up and treatment. Methods:
Philipp Krisai, MD, Linda S.B. Johnson, MD, PhD, Giorgio Moschovitis, MD, MSc, Alexander Benz, MD, MSc, Chinthanie Ramasundarahettige, MSc, William F. McIntyre, MD, Jorge A. Wong, MD, MPH, David Conen, MD, MPH, Christian Sticherling, MD, Stuart J. Connolly, MD, Jeff S. Healey, MD, MSc   +10 more
doaj   +1 more source

An Autologous, Vascularized and Immunocompetent Tissue Engineered Skin to Highlight Inter‐Individual Variability to Better Understand the Human Wound Healing

Wound Repair and Regeneration, Volume 34, Issue 1, January/February 2026.
ABSTRACT In vitro tissue‐engineered skin models are valuable tools for dermatological research. Yet, they often fail to reproduce the complex interactions among vascular, immune, and cutaneous cells during the wound healing process. In addition, inter‐individual variability response remains poorly understood, limiting our knowledge of the genetic and ...
Emilie Attiogbe, Elodie Mareux, Sébastien Larochelle, Adèle Mauroux, Sandrine Gofflo, Carine Mainzer, Sylvie Bordes, Brigitte Closs, Caroline Gilbert, Véronique J. Moulin   +9 more
wiley   +1 more source