Results 21 to 30 of about 2,153 (178)

Membrane estrogen receptor-α contributes to female protection against high-fat diet-induced metabolic disorders

Frontiers in Endocrinology, 2023
BackgroundEstrogen Receptor α (ERα) is a significant modulator of energy balance and lipid/glucose metabolisms. Beyond the classical nuclear actions of the receptor, rapid activation of intracellular signaling pathways is mediated by a sub-fraction of ...
Aurélie Fabre, Blandine Tramunt, Blandine Tramunt, Alexandra Montagner, Céline Mouly, Elodie Riant, Marie-Lou Calmy, Marine Adlanmerini, Coralie Fontaine, Rémy Burcelin, Françoise Lenfant, Jean-François Arnal, Pierre Gourdy, Pierre Gourdy   +13 more
doaj   +1 more source

Structural Alterations Associated With Cardiovascular Autonomic Failure in Multiple System Atrophy. [PDF]

Eur J Neurol
ABSTRACT Background Early severe autonomic failure (AF) in multiple system atrophy (MSA) is a risk factor for poor survival. Postmortem studies suggested that AF is related to the degeneration of preganglionic autonomic neurons of the brainstem and spinal cord. Objectives Characterize cerebral alterations on brain imaging associated with cardiovascular
Georges C, Arribarat G, Kermorgant M, Bonneville F, Fabbri M, Foubert A, Meissner W, Rascol O, Traon AP, Péran P.   +9 more
europepmc   +2 more sources

Effects of Chemical Structures Interacting with Amine Oxidases on Glucose, Lipid and Hydrogen Peroxide Handling by Human Adipocytes

Molecules, 2022
Benzylamine is a natural molecule present in food and edible plants, capable of activating hexose uptake and inhibiting lipolysis in human fat cells.
Christian Carpéné, Pénélope Viana, Zsuzsa Iffiú-Soltesz, Pál Tapolcsányi, Anna Ágota Földi, Péter Mátyus, Petra Dunkel   +6 more
doaj   +1 more source

Oral Microbiota: A Major Player in the Diagnosis of Systemic Diseases

Diagnostics, 2021
The oral cavity is host to a complex and diverse microbiota community which plays an important role in health and disease. Major oral infections, i.e., caries and periodontal diseases, are both responsible for and induced by oral microbiota dysbiosis ...
Charlotte Thomas, Matthieu Minty, Alexia Vinel, Thibault Canceill, Pascale Loubières, Remy Burcelin, Myriam Kaddech, Vincent Blasco-Baque, Sara Laurencin-Dalicieux   +8 more
doaj   +1 more source

Cardiovascular and Renal Risk Factors and Complications Associated With COVID-19

CJC Open, 2021
The current COVID-19 pandemic, caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) virus, represents the largest medical challenge in decades.
Rhian M. Touyz, MBBCh, PhD, Marcus O.E. Boyd, Tomasz Guzik, MD, PhD, Sandosh Padmanabhan, MD, PhD, Linsay McCallum, MBChB, Christian Delles, MD, Patrick B. Mark, MBChB, PhD, John R. Petrie, MBChB, PhD, Francisco Rios, PhD, Augusto C. Montezano, PhD, Robert Sykes, MBChB, BMedSci, Colin Berry, MBChB, PhD   +11 more
doaj   +1 more source

Comparative atrial fibrillation risk across Bruton's tyrosine kinase inhibitors in B‐cell malignancies: A nationwide population‐based study

British Journal of Haematology, EarlyView.
Real‐world nationwide data in B‐cell malignancies reveal a markedly increased 1‐year incidence of hospitalized atrial fibrillation with ibrutinib compared with second‐generation Bruton's tyrosine kinase inhibitors and venetoclax, arguing for closer cardiac surveillance.
Yoann Zelmat, Loic Ysebaert, Paul Gautier, Agnes Sommet, Margaux Lafaurie, Fabien Despas   +5 more
wiley   +1 more source

Ex vivo Analysis of Lipolysis in Human Subcutaneous Adipose Tissue Explants

Bio-Protocol, 2018
Most studies of human adipose tissue (AT) metabolism and functionality have been performed in vitro on isolated mature adipocyte or in situ using the microdialysis technique (Lafontan, 2012). However, these approaches have several limitations. The use of
Pauline Decaunes, Anne Bouloumié, Mikael Ryden, Jean Galitzky   +3 more
doaj   +1 more source

Deciphering pro‐arrhythmogenic mechanisms of EPAC in human atrial cardiomyocytes

The Journal of Physiology, EarlyView.
Abstract figure legend This study aimed to investigate the effect of exchange proteins directly activated by cAMP (EPAC) on the regulation of human atrial cardiomyocyte electrophysiology and their potential involvement in the onset of atrial fibrillation (AF).
Arthur Boileve, Margaux Aize, Maximin Détrait, Laura Brard, Adrien Leboyer, Pierre‐Antoine Dupont, Alexandre Lebrun, Vladimir Saplacan, Christophe Simard, Fabien Brette, Frank Lezoualc'h, Laurent Sallé   +11 more
wiley   +1 more source

Platelet Versus Megakaryocyte: Who Is the Real Bandleader of Thromboinflammation in Sepsis?

Cells, 2022
Platelets are mainly known for their key role in hemostasis and thrombosis. However, studies over the last two decades have shown their strong implication in mechanisms associated with inflammation, thrombosis, and the immune system in various neoplastic,
Cédric Garcia, Baptiste Compagnon, Michaël Poëtte, Marie-Pierre Gratacap, François-Xavier Lapébie, Sophie Voisin, Vincent Minville, Bernard Payrastre, Fanny Vardon-Bounes, Agnès Ribes   +9 more
doaj   +1 more source

Comparison of Labscan 200 and FlexMap 3D Luminex for Anti‐HLA Antibodies Monitoring

HLA, Volume 107, Issue 5, May 2026.
ABSTRACT The new Luminex model FlexMap 3D is progressively replacing the previous Luminex generation in HLA laboratories for the detection and identification of anti‐HLA antibodies. FlexMap 3D Luminex promises a higher degree of sensitivity, which may lead to greater mean fluorescence intensities, depending on the anti‐HLA beads kit supplier.
J. Milhès, L. Duclercq, S. Blavy, A. Del Bello, N. Kamar, C. Bouthemy, N. Congy‐Jolivet   +6 more
wiley   +1 more source