Results 11 to 20 of about 10,673 (213)

Acides gras oméga 3 et maladies cardiovasculaires : approches épidémiologiques [PDF]

Oléagineux, Corps gras, Lipides, 2004
La prise alimentaire d’acides gras oméga 3 a de nombreuses conséquences biologiques en particulier dans les domaines intéressant le risque cardiovasculaire (thrombose, métabolisme lipidique, inflammation). A partir de l’énorme littérature épidémiologique
Ducimetiere Pierre
doaj   +2 more sources

L'infection a cytomegalovirus humaine et le risque de maladies cardiovasculaires [PDF]

, 2022
Cardiovascular diseases are the main causes of mortality and morbidity in the world. Despite complex public health program policies, the modification of the lifestyle of the population, and the increasingly aggressive therapeutic correction of classic ...
Cristescu, Carmen
core   +4 more sources

Estrogen Receptor and Vascular Aging

Frontiers in Aging, 2021
Cardiovascular diseases remain an age-related pathology in both men and women. These pathologies are 3-fold more frequent in men than in women before menopause, although this difference progressively decreases after menopause.
Morgane Davezac, Melissa Buscato, Rana Zahreddine, Patrick Lacolley, Daniel Henrion, Francoise Lenfant, Jean-Francois Arnal, Coralie Fontaine   +7 more
doaj   +1 more source

Rôle du récepteur TREM-1 dans les maladies cardiovasculaires [PDF]

, 2022
La réponse immunitaire innée joue un rôle important dans le déclenchement et la progression des maladies cardiovasculaires ainsi que dans leurs complications, potentiellement mortelles.
Jérémie Joffre, Joffre, Jérémie, Marie Vandestienne, Hafid Ait-Oufella, Vandestienne, Marie, Ait-Oufella, Hafid, Jérémie Lemarié, Lemarié, Jérémie   +7 more
core   +1 more source

Atomic force microscopy-single-molecule force spectroscopy unveils GPCR cell surface architecture

Communications Biology, 2022
Atomic force microscopy-based single molecule force spectroscopy reveals the unfolding of G-protein coupled receptors on the surface of living mammalian cells.
Etienne Dague, Véronique Pons, Alexandre Roland, Jean-Marc Azaïs, Silvia Arcucci, Véronique Lachaize, Samuel Velmont, Emmanuelle Trevisiol, Du N’Guyen, Jean-Michel Sénard, Céline Galés   +10 more
doaj   +1 more source

Ibrutinib does not prevent kidney fibrosis following acute and chronic injury

Scientific Reports, 2021
Recent studies suggested that ibrutinib, a Bruton tyrosine kinase (BTK) inhibitor, developed for the treatment of chronic lymphocytic leukemia, may prevent NLRP3 inflammasome activation in macrophages, IL-1β secretion and subsequent development of ...
Julie Belliere, Audrey Casemayou, Eloïse Colliou, Hélène El Hachem, Clément Kounde, Alexis Piedrafita, Guylène Feuillet, Joost P. Schanstra, Stanislas Faguer   +8 more
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Intermittent Fasting Resolves Dyslipidemia and Atherogenesis in Apolipoprotein E-Deficient Mice in a Diet-Dependent Manner, Irrespective of Sex

Cells, 2023
In humans and animal models, intermittent fasting (IF) interventions promote body weight loss, improve metabolic health, and are thought to lower cardiovascular disease risk.
Jules Mérian, Lamia Ghezali, Charlotte Trenteseaux, Thibaut Duparc, Diane Beuzelin, Vanessa Bouguetoch, Guillaume Combes, Nabil Sioufi, Laurent O. Martinez, Souad Najib   +9 more
doaj   +1 more source

Platelet P2Y1 receptor exhibits constitutive G protein signaling and β-arrestin 2 recruitment

BMC Biology, 2023
Background Purinergic P2Y1 and P2Y12 receptors (P2Y1-R and P2Y12-R) are G protein-coupled receptors (GPCR) activated by adenosine diphosphate (ADP) to mediate platelet activation, thereby playing a pivotal role in hemostasis and thrombosis. While P2Y12-R
Agnès Ribes, Cédric Garcia, Marie-Pierre Gratacap, Evi Kostenis, Laurent O. Martinez, Bernard Payrastre, Jean-Michel Sénard, Céline Galés, Véronique Pons   +8 more
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Ephrin-B1 regulates the adult diastolic function through a late postnatal maturation of cardiomyocyte surface crests

eLife, 2023
The rod-shaped adult cardiomyocyte (CM) harbors a unique architecture of its lateral surface with periodic crests, relying on the presence of subsarcolemmal mitochondria (SSM) with unknown role.
Clement Karsenty, Celine Guilbeau-Frugier, Gaël Genet, Marie-Helene Seguelas, Philippe Alzieu, Olivier Cazorla, Alexandra Montagner, Yuna Blum, Caroline Dubroca, Julile Maupoint, Blandine Tramunt, Marie Cauquil, Thierry Sulpice, Sylvain Richard, Silvia Arcucci, Remy Flores-Flores, Nicolas Pataluch, Romain Montoriol, Pierre Sicard, Antoine Deney, Thierry Couffinhal, Jean-Michel Senard, Celine Galés   +22 more
doaj   +1 more source

Remodeling of Ion Channel Trafficking and Cardiac Arrhythmias

Cells, 2021
Both inherited and acquired cardiac arrhythmias are often associated with the abnormal functional expression of ion channels at the cellular level. The complex machinery that continuously traffics, anchors, organizes, and recycles ion channels at the ...
Camille E. Blandin, Basile J. Gravez, Stéphane N. Hatem, Elise Balse   +3 more
doaj   +1 more source