Experimental Models of Microvascular Immunopathology: The Example of Cerebral Malaria. [PDF]
, 2014 Human cerebral malaria is a severe and often lethal complication of Plasmodium falciparum infection. Complex host and parasite interactions should the precise mechanisms involved in the onset of this neuropathology.
Combes, V, El-Assaad, F, Grau, GE
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Plasma mEV levels in Ghanain malaria patients with low parasitaemia are higher than those of healthy controls, raising the potential for parasite markers in mEVs as diagnostic targets [PDF]
, 2019 © 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of The International Society for Extracellular Vesicles.
Antwi-Baffour, Samuel +5 more
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CNS Neuroscience &Therapeutics, Volume 31, Issue 6, June 2025.Microglia exhibit distinct transcriptional and morphological heterogeneity in experimental cerebral malaria (ECM) compared to physiological microglia. A unique subtype of ECM‐associated microglia, characterized by CXCL10highTNFαhighKi67+, mediates the recruitment and sustained activation of CD8+ T cells through ongoing interactions, exacerbating ...
Yi Wang +13 more
wiley +1 more source
Imaging features of fulminant cerebral malaria: A case report
Radiology Case Reports, 2023 Cerebral malaria is associated with high mortality and morbidity in patients infected with Plasmodium Falciparum. The mechanisms of cerebral malaria include sequestration of parasitized red blood cells in brain capillaries, production of cytokines ...
Ahmed El Beltagi +4 more
doaj
Age as a Risk Factor for Severe Manifestations and Fatal Outcome of Falciparum Malaria in European Patients: Observations from TropNetEurop and SIMPID Surveillance Data [PDF]
, 2017 Previous studies have indicated that age is a risk factor for severe falciparum malaria in nonimmune patients. The objectives of this study were to reevaluate previous findings with a larger sample and to find out how strongly clinical outcomes for ...
Behrens, R. H. +34 more
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A human complement receptor 1 polymorphism that reduces Plasmodium falciparum rosetting confers protection against severe malaria [PDF]
, 2004 Parasitized red blood cells (RBCs) from children suffering from severe malaria often adhere to complement receptor 1 (CR1) on uninfected RBCs to form clumps of cells known as "rosettes." Despite a well documented association between rosetting and severe ...
A. O'Donnell +49 more
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Plasmodium vivax cerebral malaria with pancytopenia in the peruvian amazon: case report. [PDF]
Rev Peru Med Exp Salud Publica, 2022 Paredes-Obando M +9 more
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Impact of methylene blue and atorvastatin combination therapy on the apparition of cerebral malaria in a murine model [PDF]
, 2013 International audienceBackgroundProveblue®, a methylene blue dye that complies with European Pharmacopoeia and contains limited organic impurities and heavy metals of recognized toxicity, showed in vitro synergy against Plasmodium falciparum when ...
Briolant, Sébastien +3 more
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Cerebral malaria admissions in Papua New Guinea may show inter-annual cyclicity: An example of about a 1.5-year cycle for malaria incidence in Burundi [PDF]
, 2008 Best available descriptions of malaria incidence and mortality dynamics are important to better plan and evaluate the implementation of programs to monitor (e.g., remote sensing) and control the disease, especially in endemic zones.
Borislav D. Dimitrov +1 more
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