Cytoadherence Properties of Plasmodium knowlesi-Infected Erythrocytes
Frontiers in Microbiology, 2022 Plasmodium knowlesi is responsible for zoonotic malaria infections that are potentially fatal. While the severe pathology of falciparum malaria is associated with cytoadherence phenomena by Plasmodium falciparum-infected erythrocytes (IRBC), information ...
Wenn-Chyau Lee +2 more
exaly +3 more sources
Knobs, Adhesion, and Severe Falciparum Malaria [PDF]
Tropical Medicine and Infectious Disease, 2023 Plasmodium falciparum can cause a severe disease with high mortality. A major factor contributing to the increased virulence of P. falciparum, as compared to other human malarial parasites, is the sequestration of infected erythrocytes in the capillary ...
Mark F. Wiser
doaj +2 more sources
Distinct features of the host-parasite interactions between nonadherent and adherent Trichomonas vaginalis isolates. [PDF]
PLoS Neglected Tropical Diseases, 2023 Cytoadherence of Trichomonas vaginalis to human vaginal epithelial cells (hVECs) was previously shown to involve surface lipoglycans and several reputed adhesins on the parasite.
Hong-Ming Hsu +10 more
doaj +2 more sources
The role of periostin (OSF-2) in the cytoadherence phenomena mediated by malaria parasites [PDF]
Frontiers in Cellular and Infection MicrobiologyIntroductionThe pathogenesis of severe malaria is primarily attributed to the cytoadherence properties of Plasmodium-infected erythrocytes (IRBC), which include rosetting and IRBC-endothelial cytoadherence.
Zhi-Ying Phong +12 more
doaj +2 more sources
An Atypical F-Actin Capping Protein Modulates Cytoskeleton Behaviors Crucial for Trichomonas vaginalis Colonization [PDF]
Microbiology Spectrum, 2023 Cytoadherence and migration are crucial for pathogens to establish colonization in the host. In contrast to a nonadherent isolate of Trichomonas vaginalis, an adherent one expresses more actin-related machinery proteins with more active flagellate ...
Kai-Hsuan Wang +8 more
doaj +2 more sources
Cerebral malaria is associated with differential cytoadherence to brain endothelial cells
EMBO Molecular Medicine, 2019 Sequestration of Plasmodium falciparum‐infected erythrocytes (IE) within the brain microvasculature is a hallmark of cerebral malaria (CM). Using a microchannel flow adhesion assay with TNF‐activated primary human microvascular endothelial cells, we ...
Janet Storm +2 more
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Phenotypic and genotypic characterization of Plasmodium falciparum field isolates lacking pfhrp2 gene [PDF]
Malaria JournalBackground The Plasmodium falciparum phenotypic characteristics (cytoadherence and rosetting), and the concentration of Histidine Rich Protein 2 (HRP2) in serum are associated with severe malaria in regions like Africa and Asia.
Jorge Bendezu +5 more
doaj +2 more sources
Different PfEMP1-expressing Plasmodium falciparum variants induce divergent endothelial transcriptional responses during co-culture. [PDF]
PLoS ONE, 2023 The human malaria parasite Plasmodium falciparum is responsible for the majority of mortality and morbidity caused by malaria infection and differs from other human malaria species in the degree of accumulation of parasite-infected red blood cells in the
Basim Othman +12 more
doaj +2 more sources
A preliminary study of the immunogenic response of plant-derived multi-epitopic peptide vaccine candidate of Mycoplasma gallisepticum in chickens [PDF]
Frontiers in Plant Science, 2023 Mycoplasma gallisepticum (MG) is responsible for chronic respiratory disease in avian species, characterized by symptoms like respiratory rales and coughing. Existing vaccines for MG have limited efficacy and require multiple doses.
Susithra Priyadarhni Mugunthan +4 more
doaj +2 more sources
Sticking for a Cause: The Falciparum Malaria Parasites Cytoadherence Paradigm
Frontiers in Immunology, 2019 After a successful invasion, malaria parasite Plasmodium falciparum extensively remodels the infected erythrocyte cellular architecture, conferring cytoadhesive properties to the infected erythrocytes. Cytoadherence plays a central role in the parasite's
Wenn-Chyau Lee +2 more
exaly +3 more sources