Results 41 to 50 of about 2,810 (108)

A role for fetal hemoglobin and maternal immune IgG in infant resistance to Plasmodium falciparum malaria. [PDF]

PLoS ONE, 2011
In Africa, infant susceptibility to Plasmodium falciparum malaria increases substantially as fetal hemoglobin (HbF) and maternal immune IgG disappear from circulation.
Chanaki Amaratunga, Tatiana M Lopera-Mesa, Nathaniel J Brittain, Rushina Cholera, Takayuki Arie, Hisashi Fujioka, Jeffrey R Keefer, Rick M Fairhurst   +7 more
doaj   +1 more source

Aptamer Technology: Adjunct Therapy for Malaria

Biomedicines, 2017
Malaria is a life-threatening parasitic infection occurring in the endemic areas, primarily in children under the age of five, pregnant women, and patients with human immunodeficiency virus and acquired immunodeficiency syndrome (HIV)/(AIDS) as well as ...
Nik Abdul Aziz Nik Kamarudin, Nurul Adila Mohammed, Khairul Mohd Fadzli Mustaffa   +2 more
doaj   +1 more source

Plasmodium Falciparum: Adhesion Phenotype of Infected Erythrocytes Using Classical and Mini-Column Cytoadherence Techniques

Iranian Journal of Parasitology, 2013
Background: Cytoadherence of Plasmodium falciparum- infected erythrocytes to host cells is an impor­tant trait for parasite survival and has a major role in pathology of malaria disease. Infections with P.
N Kalantari, S Ghaffari, M Bayani
doaj   +2 more sources

Cytoadherence characteristics to endothelial receptors ICAM-1 and CD36 of Plasmodium falciparum populations from severe and uncomplicated malaria cases

Parasite, 2008
The adhesion of infected red blood cells (IRBCs) to the cell lining of microvasculature is thought to play a central role in the pathogenesis of severe malaria.
Cojean S., Jafari-Guemouri S., Le Bras J., Durand R.   +3 more
doaj   +1 more source

Plasma-derived extracellular vesicles from Plasmodium vivax patients signal spleen fibroblasts via NF-kB facilitating parasite cytoadherence

Nature Communications, 2020
Extracellular vesicles (EVs) in plasma can affect pathogenesis of parasites, but details remain unclear. Here, Toda et al. characterize plasma-derived EVs from Plasmodium vivax patients and show that PvEVs are preferentially taken up by human spleen ...
Haruka Toda, Miriam Diaz-Varela, Joan Segui-Barber, Wanlapa Roobsoong, Barbara Baro, Susana Garcia-Silva, Alicia Galiano, Melisa Gualdrón-López, Anne C. G. Almeida, Marcelo A. M. Brito, Gisely Cardoso de Melo, Iris Aparici-Herraiz, Carlos Castro-Cavadía, Wuelton Marcelo Monteiro, Eva Borràs, Eduard Sabidó, Igor C. Almeida, Jakub Chojnacki, Javier Martinez-Picado, Maria Calvo, Pilar Armengol, Jaime Carmona-Fonseca, Maria Fernanda Yasnot, Ricardo Lauzurica, Antonio Marcilla, Hector Peinado, Mary R. Galinski, Marcus V. G. Lacerda, Jetsumon Sattabongkot, Carmen Fernandez-Becerra, Hernando A. del Portillo   +30 more
doaj   +1 more source

Var transcription profiling of Plasmodium falciparum 3D7: assignment of cytoadherent phenotypes to dominant transcripts

Malaria Journal, 2008
Background Cytoadherence of Plasmodium falciparum-infected red blood cells is mediated by var gene-encoded P. falciparum erythrocyte membrane protein-1 and host receptor preference depends in most cases on which of the 50–60 var genes per genome is ...
Wunderlich Gerhard, Albrecht Letusa, Gölnitz Uta   +2 more
doaj   +1 more source

Editorial: Frontiers in malaria research

Frontiers in Microbiology, 2023
Ritu Gill, Rachna Hora, Mahmood M. Alam, Abhisheka Bansal, Tarun Kumar Bhatt, Ashwani Sharma   +5 more
doaj   +1 more source

Structural analysis of P. falciparum KAHRP and PfEMP1 complexes with host erythrocyte spectrin suggests a model for cytoadherent knob protrusions.

PLoS Pathogens, 2017
Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) and Knob-associated Histidine-rich Protein (KAHRP) are directly linked to malaria pathology. PfEMP1 and KAHRP cluster on protrusions (knobs) on the P.
Erin E Cutts, Niklas Laasch, Dirk M Reiter, Raphael Trenker, Leanne M Slater, Phillip J Stansfeld, Ioannis Vakonakis   +6 more
doaj   +1 more source

Signal transduction in Plasmodium-Red Blood Cells interactions and in cytoadherence

Anais da Academia Brasileira de Ciências, 2012
Malaria is responsible for more than 1.5 million deaths each year, especially among children (Snow et al. 2005). Despite of the severity of malaria situation and great effort to the development of new drug targets (Yuan et al.
Laura N. Cruz, Yang Wu, Alister G. Craig, Célia R.S. Garcia   +3 more
doaj  

PIP2 regulating calcium signal modulates actin cytoskeleton-dependent cytoadherence and cytolytic capacity in the protozoan parasite Trichomonas vaginalis. [PDF]

PLoS Pathog, 2023
Chen YJ, Wu KY, Lin SF, Huang SH, Hsu HC, Hsu HM.   +5 more
europepmc   +1 more source