Results 41 to 50 of about 50,084 (222)

A functional polymorphism in the IL1B gene promoter, IL1B -31C>T, is not associated with cerebral malaria in Thailand

open access: yesMalaria Journal, 2005
Background IL-1β and IL-1RA levels are higher in the serum of cerebral malaria patients than in patients with mild malaria. Recently, the level of IL1B expression was reported to be influenced by a polymorphism in the promoter of IL1, IL1B -31C>T ...
Tangpukdee Noppadon   +7 more
doaj   +1 more source

Cerebral Malaria and Neuronal Implications of Plasmodium Falciparum Infection: From Mechanisms to Advanced Models

open access: yesAdvanced Science, 2022
Reorganization of host red blood cells by the malaria parasite Plasmodium falciparum enables their sequestration via attachment to the microvasculature.
Oscar Bate Akide Ndunge   +2 more
doaj   +1 more source

Cerebral malaria

open access: yesBiomedicine & Pharmacotherapy, 1989
Cerebral malaria is the most important manifestation of severe Plasmodium falciparum infection. The clinical picture in South East Asian adults differs from that in African children. The children are more likely to have abnormal brain stem reflexes, signs suggestive of cerebral herniation, and raised CSF opening pressure, and to suffer persistent ...
openaire   +4 more sources

Delayed gastric emptying time in adult cerebral falciparum malaria [PDF]

open access: yesJournal of Vector Borne Diseases, 2012
Objective: We hypothesize that upper gastrointestinal symptoms in cerebral malaria are due to gastric motordysfunction. But gastric motility studies in cerebral malaria are scarce.Methods: We determined gastric emptying half-time (GET½) of liquid meals ...
M.K. Mohapatra , P.C. Dash , S.C. Mohapatro & R.N. Mishra
doaj  

Plasmodium coatneyi-infected rhesus monkeys: a primate modelfor human cerebral malaria

open access: yesMemorias do Instituto Oswaldo Cruz, 1992
Although several animal models for human cerebral malaria have been proposed in the past, name have shown pathological findings that are similar to those seen in humans.
Masamichi Aikawa   +8 more
doaj   +1 more source

Critical roles of endogenous glucocorticoids for disease tolerance in malaria

open access: yes, 2019
During malaria, the hypothalamic-pituitary-adrenal (HPA) axis is activated and glucocorticoid (GC) levels are increased, but their essential roles have been largely overlooked.
De Bosscher, Karolien   +4 more
core   +1 more source

Neuregulin-1 attenuates experimental cerebral malaria (ECM) pathogenesis by regulating ErbB4/AKT/STAT3 signaling. [PDF]

open access: yes, 2018
BACKGROUND:Human cerebral malaria (HCM) is a severe form of malaria characterized by sequestration of infected erythrocytes (IRBCs) in brain microvessels, increased levels of circulating free heme and pro-inflammatory cytokines and chemokines, brain ...
Cespedes, Juan Carlos   +5 more
core   +1 more source

Cerebral malaria in children

open access: yesThe Lancet, 1990
Cerebral malaria is a rapidly progressive encephalopathy with up to 50% mortality. A cardinal feature is the massing of red cells containing mature Plasmodium falciparum within the cerebral capillaries. Adhesion of these parasitised red cells to endothelium, an event which may initiate cerebral malaria, is being studied at the molecular level. However,
Phillips, R, Solomon, T
openaire   +4 more sources

Long-term effect of uncomplicated Plasmodium berghei ANKA malaria on memory and anxiety-like behaviour in C57BL/6 mice

open access: yesParasites & Vectors, 2018
Background Cerebral malaria, the main complication of Plasmodium falciparum infection in humans, is associated with persistent neurocognitive sequels both in human disease and the murine experimental model.
Luciana Pereira de Sousa   +6 more
doaj   +1 more source

Elevated plasma von Willebrand factor and propeptide levels in Malawian children with malaria. [PDF]

open access: yesPLoS ONE, 2011
In spite of the significant mortality associated with Plasmodium falciparum infection, the mechanisms underlying severe disease remain poorly understood.
Happy T Phiri   +11 more
doaj   +1 more source

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