Results 41 to 50 of about 50,084 (222)
Background IL-1β and IL-1RA levels are higher in the serum of cerebral malaria patients than in patients with mild malaria. Recently, the level of IL1B expression was reported to be influenced by a polymorphism in the promoter of IL1, IL1B -31C>T ...
Tangpukdee Noppadon+7 more
doaj +1 more source
Reorganization of host red blood cells by the malaria parasite Plasmodium falciparum enables their sequestration via attachment to the microvasculature.
Oscar Bate Akide Ndunge+2 more
doaj +1 more source
Cerebral malaria is the most important manifestation of severe Plasmodium falciparum infection. The clinical picture in South East Asian adults differs from that in African children. The children are more likely to have abnormal brain stem reflexes, signs suggestive of cerebral herniation, and raised CSF opening pressure, and to suffer persistent ...
openaire +4 more sources
Delayed gastric emptying time in adult cerebral falciparum malaria [PDF]
Objective: We hypothesize that upper gastrointestinal symptoms in cerebral malaria are due to gastric motordysfunction. But gastric motility studies in cerebral malaria are scarce.Methods: We determined gastric emptying half-time (GET½) of liquid meals ...
M.K. Mohapatra , P.C. Dash , S.C. Mohapatro & R.N. Mishra
doaj
Plasmodium coatneyi-infected rhesus monkeys: a primate modelfor human cerebral malaria
Although several animal models for human cerebral malaria have been proposed in the past, name have shown pathological findings that are similar to those seen in humans.
Masamichi Aikawa+8 more
doaj +1 more source
Critical roles of endogenous glucocorticoids for disease tolerance in malaria
During malaria, the hypothalamic-pituitary-adrenal (HPA) axis is activated and glucocorticoid (GC) levels are increased, but their essential roles have been largely overlooked.
De Bosscher, Karolien+4 more
core +1 more source
Neuregulin-1 attenuates experimental cerebral malaria (ECM) pathogenesis by regulating ErbB4/AKT/STAT3 signaling. [PDF]
BACKGROUND:Human cerebral malaria (HCM) is a severe form of malaria characterized by sequestration of infected erythrocytes (IRBCs) in brain microvessels, increased levels of circulating free heme and pro-inflammatory cytokines and chemokines, brain ...
Cespedes, Juan Carlos+5 more
core +1 more source
Cerebral malaria is a rapidly progressive encephalopathy with up to 50% mortality. A cardinal feature is the massing of red cells containing mature Plasmodium falciparum within the cerebral capillaries. Adhesion of these parasitised red cells to endothelium, an event which may initiate cerebral malaria, is being studied at the molecular level. However,
Phillips, R, Solomon, T
openaire +4 more sources
Background Cerebral malaria, the main complication of Plasmodium falciparum infection in humans, is associated with persistent neurocognitive sequels both in human disease and the murine experimental model.
Luciana Pereira de Sousa+6 more
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Elevated plasma von Willebrand factor and propeptide levels in Malawian children with malaria. [PDF]
In spite of the significant mortality associated with Plasmodium falciparum infection, the mechanisms underlying severe disease remain poorly understood.
Happy T Phiri+11 more
doaj +1 more source