Results 51 to 60 of about 50,084 (222)
Malaria infection of the Central Nervous System (CNS) can cause a severe neurological syndrome termed Cerebral Malaria (CM). The central neuropathological feature of CM is the preferential sequestration of parasitised red blood cells (PRBC) in the cerebral microvasculature.
openaire +3 more sources
Hypoglycaemia and cerebral malaria [PDF]
Summary A patient with severe hypoglycaemia complicating cerebral malaria is reported. No other recognized cause of hypoglycaemia was detected during life or at autopsy. This case adds to the existing evidence that, through several possible mechanisms, cerebral malaria can give rise to life-threatening hypoglycaemia.
openaire +4 more sources
Shifts in the clinical epidemiology of severe malaria after scaling up control strategies in Mali
A decrease in malaria incidence following implementation of control strategies such as use of artemisinin-based combination therapies, insecticide-impregnated nets, intermittent preventive treatment during pregnancy and seasonal malaria chemoprevention ...
Drissa Coulibaly+14 more
doaj +1 more source
Diagnosing Severe Falciparum Malaria in Parasitaemic African Children: A Prospective Evaluation of Plasma PfHRP2 Measurement. [PDF]
In African children, distinguishing severe falciparum malaria from other severe febrile illnesses with coincidental Plasmodium falciparum parasitaemia is a major challenge. P. falciparum histidine-rich protein 2 (PfHRP2) is released by mature sequestered
Amos, Ben+23 more
core +5 more sources
Molecular and functional landscape of BD progression and severity based on in‐depth proteomics. Tree boosting machine learning models with favorable performance in BD diagnosis and stratification. Efficient biomarker panels for BD diagnosis and stratification. .
Linlin Cheng+6 more
wiley +1 more source
IL-33 signaling regulates innate and adaptive immunity to Cryptococcus neoformans.
Susceptibility to progressive infection with the fungus Cryptococcus neoformans is associated with an allergic pattern of lung inflammation, yet the factors that govern this host response are not clearly understood.
Duerr, Claudia U+5 more
core +1 more source
Neuropsychiatric diseases are common among forcibly displaced persons, and a better understanding is needed to improve screening and treatment efforts. We performed a retrospective cross‐sectional study at a single academic center looking at neuropsychiatric diagnoses of United States resettled refugees presenting for their domestic medical examination.
Noor F. Shaik+2 more
wiley +1 more source
Background Plasmodium falciparum malaria remains a major health problem in Africa. The mechanisms of pathogenesis are not fully understood. Transcriptomic studies may provide new insights into molecular pathways involved in the severe form of the disease.
Alassane Thiam+11 more
doaj +1 more source
Assessment of severe malaria in a multicenter, phase III, RTS, S/AS01 malaria candidate vaccine trial: case definition, standardization of data collection and patient care. [PDF]
BACKGROUND\ud \ud An effective malaria vaccine, deployed in conjunction with other malaria interventions, is likely to substantially reduce the malaria burden. Efficacy against severe malaria will be a key driver for decisions on implementation.
Amanda Leach+18 more
core +4 more sources
Abstract Many newcomer children spend a ‘silent year’ in elementary school classrooms while they adjust to a new culture and language. This often delays inclusion in learning and forming friendships with peers. For refugee children with disabilities (RCDs) this phase may last for 3 years or more, impacting their mental health and sense of belonging ...
Susan Barber
wiley +1 more source