Results 61 to 70 of about 50,084 (222)
Differences in gene transcriptomic pattern of Plasmodium falciparum in children with cerebral malaria and asymptomatic carriers. [PDF]
PLoS ONE, 2014 The mechanisms underlying the heterogeneity of clinical malaria remain largely unknown. We hypothesized that differential gene expression contributes to phenotypic variation of parasites which results in a specific interaction with the host, leading to ...
Talleh Almelli +13 more
doaj +1 more source
Chemistry &Biodiversity, EarlyView.ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves +3 more
wiley +1 more source
Cerebral malaria: Gamma-interferon redux [PDF]
, 2014 There are two theories that seek to explain the pathogenesis of cerebral malaria, the mechanical obstruction hypothesis and the immunopathology hypothesis.
Bakmiwewa, S +8 more
core +2 more sources
The upside of epilepsy: Theories of an evolutionary paradox
Epilepsia Open, EarlyView.Abstract The persistence of common, heritable conditions, like epilepsy, that are associated with reduced reproductive fitness is an evolutionary paradox. Endogenous analgesic, anti‐depressant, and inflammatory mechanisms able to repair compromised functions can offer advantages in unexpected crises.
Alyssa Ailion +3 more
wiley +1 more source
Inter-Relationships of Cardinal Features and Outcomes of Symptomatic Pediatric Plasmodium falciparum Malaria in 1,933 Children in Kampala, Uganda [PDF]
, 2013 Malaria remains a challenging diagnosis with variable clinical presentation and a wide spectrum of disease severity. Using a structured case report form, we prospectively assessed 1,933 children at Mulago Hospital in Kampala, Uganda with acute Plasmodium
Cserti-Gazdewich, Christine M. +8 more
core +2 more sources
International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 408-420, April 2025.Abstract Objective Birth asphyxia is one of the leading causes of death for neonates worldwide. Lack of an objective cost effective test to predict poor newborn outcomes at birth affects the ability to respond appropriately. This study determined predictive values of umbilical cord arterial lactate in relation to adverse neonatal outcomes. Methods This
Elizabeth Ayebare +7 more
wiley +1 more source
Malaria Journal, 2009 Background Interleukin-12 (IL-12), a heterodimeric cytokine composed of p35 and p40 subunits, has been thought to play an important role in the pathogenesis of malaria. The IL-12p40 subunit is encoded by the IL12B gene.
Tsuchiya Naoyuki +5 more
doaj +1 more source
Angiotensin II Moderately Decreases Plasmodium Infection and Experimental Cerebral Malaria in Mice. [PDF]
PLoS ONE, 2015 Angiotensin II, a peptide hormone that regulates blood pressure, has been proposed as a protective factor against cerebral malaria based on a genetic analysis.
Julio Gallego-Delgado +7 more
doaj +1 more source
Is there a role for bradykinin in cerebral malaria pathogenesis?
Frontiers in Cellular and Infection Microbiology, 2023 Malaria is a parasitic disease of global health significance and a leading cause of death in children living in endemic regions. Although various Plasmodium species are responsible for the disease, Plasmodium falciparum infection accounts for most severe
Alessandro de Sa Pinheiro +4 more
doaj +1 more source
Interdisciplinary Medicine, EarlyView.This article evaluates the therapeutic potential of extracellular vesicle‐like particles derived from Chinese herbal medicine (CHM‐EVLP) for a range of diseases. It underscores the significance of traditional Chinese medicine in the development of innovative formulations.
Ying‐qi Cao +6 more
wiley +1 more source