Results 71 to 80 of about 50,084 (222)

Interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) polymorphism as a genetic marker of cerebral malaria in Thai population

open access: yesAsian Pacific Journal of Tropical Medicine, 2018
Objective: To know whether the effect of interferon-induced protein with tetratricopeptide repeats (IFIT) 1 polymorphism influences the susceptibility of cerebral malaria outcome.
Saw Thu Wah   +5 more
doaj   +1 more source

Toll-like receptor polymorphisms and cerebral malaria: TLR2 Δ22 polymorphism is associated with protection from cerebral malaria in a case control study [PDF]

open access: yes, 2012
Background In malaria endemic areas, host genetics influence whether a Plasmodium falciparum-infected child develops uncomplicated or severe malaria. TLR2 has been identified as a receptor for P. falciparum-derived glycosylphosphatidylinositol (GPI), and
BT Grimberg   +32 more
core   +1 more source

Optimizing Transcranial Doppler Screening for Stroke Prevention in Young African Children with Sickle Cell Disease

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background The greatest burden of sickle cell disease (SCD) globally occurs in sub‐Saharan Africa, where significant morbidity occurs secondary to SCD‐induced vasculopathy and stroke. Transcranial doppler (TCD) ultrasound grades the severity of vasculopathy, with disease modifying therapy resulting in stroke risk reduction in high‐risk ...
Derby Tembo   +18 more
wiley   +1 more source

Characteristic abnormalities in cerebrospinal fluid biochemistry in children with cerebral malaria compared to viral encephalitis

open access: yesCerebrospinal Fluid Research, 2006
Background In developing countries where Plasmodium falciparum malaria is endemic, viral encephalitis and cerebral malaria are found in the same population, and parasitemia with Plasmodium falciparum is common in asymptomatic children.
Atmakuri RM   +3 more
doaj   +1 more source

Differential var Gene Expression in Children with Malaria and Antidromic Effects on Host Gene Expression [PDF]

open access: yes, 2017
Among 62 children with mild malaria, cerebral malaria, or severe malarial anemia, we analyzed the transcription of different var gene types. There was no difference in parasitemia level or body temperature between groups.
Beck, Hans-Peter   +5 more
core  

Natural regulatory (CD4+CD25+FOXP+) T cells control the production of pro-inflammatory cytokines during Plasmodium chabaudi adami infection and do not contribute to immune evasion. [PDF]

open access: yes, 2008
Different functions have been attributed to natural regulatory CD4+CD25+FOXP+ (Treg) cells during malaria infection. Herein, we assessed the role for Treg cells during infections with lethal (DS) and non-lethal (DK) Plasmodium chabaudi adami parasites ...
Belanger, B   +4 more
core   +1 more source

The 15‐Year Survival Advantage: Immune Resilience as a Salutogenic Force in Healthy Aging

open access: yesAging Cell, EarlyView.
Human aging shows puzzling diversity: similar aging rates yet vastly different health outcomes. Our study of ~17,500 people revealed a health‐promoting trait (more common in women) linked to strong immune resilience and high expression of TCF7, a key immune gene. This trait enables individuals to fight infections like COVID‐19 more effectively, respond
Muthu Saravanan Manoharan   +176 more
wiley   +1 more source

Hemiparesis post cerebral malaria

open access: yesThe Pan African Medical Journal, 2015
Cerebral malaria is one of the most serious complications in the Plasmodium falciparum infection. In endemic areas, the cerebral malaria interested mainly children.
Oumkaltoum Taiaa   +2 more
doaj   +1 more source

STATUS HEMATOLOGI PENDERITA MALARIA SEREBRAL

open access: yesMajalah Kedokteran Andalas, 2009
AbstrakMalaria masih merupakan masalah kesehatan masyarakat dunia. Berdasarkan klasifikasi klinis, malaria dibedakan atas malaria berat dan malaria tanpa komplikasi.
Nurhayati Nurhayati
doaj   +1 more source

Plasmodium falciparum histidine-rich protein II causes vascular leakage and exacerbates experimental cerebral malaria in mice. [PDF]

open access: yesPLoS ONE, 2017
A devastating complication of Plasmodium falciparum infection is cerebral malaria, in which vascular leakage and cerebral swelling lead to coma and often death. P. falciparum produces a protein called histidine-rich protein II (HRPII) that accumulates to
Priya Pal   +5 more
doaj   +1 more source

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