Results 91 to 100 of about 137,884 (211)

Evolutionary divergence and functional insights into the heteromeric cis‐prenyltransferase of Paramecium tetraurelia

open access: yesThe FEBS Journal, Volume 293, Issue 6, Page 1681-1707, March 2026.
Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk   +8 more
wiley   +1 more source

Consumption of Selected Healthy and Unhealthy Food Groups and Associations With Nutritional Status Among Children 2–5 Years of Age in Northern Ghana

open access: yesMaternal &Child Nutrition, Volume 22, Issue 1, March 2026.
ABSTRACT Poor diet quality may contribute to the multiple forms of malnutrition among children in Ghana. This cross‐sectional study (1) described the prevalence and frequency of consumption of fruits, vegetables, sugar‐sweetened beverages (SSB), salty snacks and sweet snacks among children 2–5 years in northern Ghana; (2) identified factors associated ...
Emily R. Becher   +11 more
wiley   +1 more source

Cross sectional study to determine chloroquine resistance among Plasmodium falciparum clinical isolates from Khartoum, Sudan [version 1; referees: 1 approved, 2 approved with reservations]

open access: yesF1000Research, 2018
Background:  Malaria continues to present a global health threat; the World Health Organization (WHO) reported 214 million cases of malaria by the year 2015 with a death rate of 438000.
Walaa Salah Abdulla Mohammed   +3 more
doaj   +1 more source

Supervised versus unsupervised antimalarial treatment with six-dose artemether-lumefantrine:pharmacokinetic and dosage-related findings from a clinical trial in Uganda [PDF]

open access: yes, 2006
BACKGROUND: A six-dose antimalarial regimen of artemether-lumefantrine (A/L) may soon become one of the most widely used drug combination in Africa, despite possible constraints with adherence and poor absorption due to inadequate nutrition, and a lack ...
Babigumira, Joseph   +13 more
core   +3 more sources

Erythrocyte Membrane Protein 3 (EMAP3) Is Exposed on the Surface of the Plasmodium berghei Infected Red Blood Cell

open access: yesMolecular Microbiology, Volume 125, Issue 3, Page 233-249, March 2026.
Erythrocyte membrane protein 3 (EMAP3) is a novel Plasmodium berghei protein that is trafficked to the outer membrane surface of the infected red blood cell (iRBC). EMAP3 is not critical for parasite growth or sequestration but offers a new scaffold for displaying Plasmodium falciparum proteins on iRBCs.
Sophia Raine C. Hernandez   +13 more
wiley   +1 more source

Drug resistance in Plasmodium falciparum from the Chittagong Hill Tracts, Bangladesh. [PDF]

open access: yes, 2004
OBJECTIVE: To assess the efficacy of antimalarial treatment and molecular markers of Plasmodium falciparum resistance in the Chittagong Hill Tracts of Bangladesh. METHODS: A total of 203 patients infected with P.
Anderson, T C   +6 more
core   +2 more sources

Artemisinin‐Based Combination Therapies in East Africa: A Systematic Review of Quality, Clinical Efficacy, and Regulatory Progress Towards Sustainable Malaria Control

open access: yesTropical Medicine &International Health, Volume 31, Issue 3, Page 254-273, March 2026.
ABSTRACT Background Malaria is a major public health issue in East Africa, leading to widespread illness and fatalities, especially among vulnerable populations such as children under 5 years of age and pregnant women. Artemisinin‐based combination therapies (ACTs) are the primary treatment modality; however, their efficacy is undermined by the ...
Yesuneh Tefera Mekasha   +5 more
wiley   +1 more source

Adherence to a Six-Dose Regimen of Artemether-Lumefantrine for Treatment of Uncomplicated Plasmodium Falciparum Malaria in Uganda. [PDF]

open access: yes, 2004
Measuring baseline levels of adherence and identifying risk factors for non-adherence are important steps before the introduction of new antimalarials. In Mbarara in southwestern Uganda, we assessed adherence to artemether-lumefantrine (Coartem) in its ...
Bajunirwe, F   +9 more
core   +2 more sources

Clathrins Are Involved in the Endocytosis of Host Cytosol in the Malaria Parasite

open access: yesTraffic, Volume 27, Issue 1, March 2026.
This study characterized clathrin function in hemoglobin uptake from host red blood cells via the malaria parasite's specific endocytosis machinery, cytostome. Clathrin heavy chain, clathrin light chain, and AP‐1 γ subunit were found associated with certain proteins known to be involved in cytostome function, and they were localized at the collars of ...
Jun Miao   +10 more
wiley   +1 more source

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