Results 51 to 60 of about 270,836 (221)

A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria

Nature, 2015
Artemisinins are the cornerstone of anti-malarial drugs. Emergence and spread of resistance to them raises risk of wiping out recent gains achieved in reducing worldwide malaria burden and threatens future malaria control and elimination on a global ...
A. Mbengue, S. Bhattacharjee, T. Pandharkar, Haining Liu, G. Estiu, R. Stahelin, Shahir S. Rizk, D. L. Njimoh, Yana Ryan, K. Chotivanich, C. Nguon, M. Ghorbal, Jose-Juan Lopez-Rubio, M. Pfrender, S. Emrich, N. Mohandas, A. Dondorp, O. Wiest, K. Haldar   +18 more
semanticscholar   +1 more source

Development of an Enzymatic Recombinase Amplification Assay for the Rapid Detection of Plasmodium Nucleic Acids

iLABMED, EarlyView.
The detection rate of enzymatic recombinase amplification (ERA) was better than that of the rapid diagnostic test. The ERA assay was more convenient than fluorescence quantitative PCR. The ERA assay can be used as a complementary tool for malaria screening and clinical diagnosis.
Xinxin Yang, Xiaoxue Lu, Junlian Yang, Wen Xu, Qian Li, Weiwei Chen   +5 more
wiley   +1 more source

Antibody responses to P. falciparum blood stage antigens and incidence of clinical malaria in children living in endemic area in Burkina Faso

BMC Research Notes, 2017
Background High parasite-specific antibody levels are generally associated with low susceptibility to Plasmodium falciparum malaria. This has been supported by several studies in which clinical malaria cases of P.
Mariama K. Cherif, Oumarou Ouédraogo, Guillaume S. Sanou, Amidou Diarra, Alphonse Ouédraogo, Alfred Tiono, David R. Cavanagh, Theisen Michael, Amadou T. Konaté, Nora L. Watson, Megan Sanza, Tina J. T. Dube, Sodiomon B. Sirima, Issa Nebié   +13 more
doaj   +1 more source

M1 macrophage features in severe Plasmodium falciparum malaria patients with pulmonary oedema

Malaria Journal, 2020
Background Pulmonary oedema (PE) is a serious complication of Plasmodium falciparum malaria which can lead to acute lung injury in severe cases. Lung macrophages are activated during malaria infection due to a complex host-immune response.
Aekkarin Klinkhamhom, Supattra Glaharn, Charit Srisook, Sumate Ampawong, Srivicha Krudsood, Stephen A. Ward, Parnpen Viriyavejakul   +6 more
doaj   +1 more source

Severe Malaria Associated with Plasmodium falciparum and P. vivax among Children in Pawe Hospital, Northwest Ethiopia

Malaria Research and Treatment, 2016
Despite rigorous effort made to control malaria for more than a century, it is still among the main public health problems in least developed regions of the world.
Getachew H. Geleta, T. Ketema
semanticscholar   +1 more source

Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire

PROTEOMICS, EarlyView.
ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley   +1 more source

Membandingkan Status Hematologis Pasien Malaria Falciparum dengan Vivax di RSUP M. Djamil Januari 2011 – Maret 2013

Jurnal Kesehatan Andalas, 2014
AbstrakMalaria merupakan masalah kesehatan yang besar di daerah tropis dan subtropis termasuk di Indonesia. Jenis malaria yang sering terjadi di daerah Sumatera adalah malaria falciparum dan vivax.
Miftahul Jannah Afdhal, Nurhayati ., Julizar .   +2 more
doaj  

Spatiotemporal dynamics of malaria in Banmauk Township, Sagaing region of Northern Myanmar: characteristics, trends, and risk factors

BMC Infectious Diseases, 2022
Background While national malaria incidence has been declining in Myanmar, some subregions within the nation continue to have high burdens of malaria morbidity and mortality.
Pyae Linn Aung, Myat Thu Soe, Thit Lwin Oo, Kyaw Thu Aung, Kyaw Kyaw Lin, Aung Thi, Lynette Menezes, Daniel M. Parker, Liwang Cui, Myat Phone Kyaw   +9 more
doaj   +1 more source

Genetic Manipulation of Non-Falciparum Human Malaria Parasites

Frontiers in Cellular and Infection Microbiology, 2021
The development of genetic manipulation of Plasmodium falciparum in the 1980s was key to study malaria biology. Genetically modified parasites have been used to study several aspects of the disease, such as red blood cell invasion, drug resistance ...
Taís Baruel Vieira, Thafne Plastina Astro, Roberto Rudge de Moraes Barros   +2 more
doaj   +1 more source

Transcriptomic evidence for modulation of host inflammatory responses during febrile Plasmodium falciparum malaria

Scientific Reports, 2016
Identifying molecular predictors and mechanisms of malaria disease is important for understanding how Plasmodium falciparum malaria is controlled. Transcriptomic studies in humans have so far been limited to retrospective analysis of blood samples from ...
T. Tran, Marcus B. Jones, A. Ongoiba, E. Bijker, R. Schats, P. Venepally, J. Skinner, S. Doumbo, Edwin Quinten, L. Visser, E. Whalen, Scott R. Presnell, Elise M O’Connell, K. Kayentao, O. Doumbo, D. Chaussabel, H. Lorenzi, T. Nutman, T. Ottenhoff, M. Haks, B. Traore, E. Kirkness, R. Sauerwein, Peter D. Crompton   +23 more
semanticscholar   +1 more source