Results 61 to 70 of about 270,836 (221)

Structural and Functional Characterization of the 28 kDa Structured Core of BmSA1, the Major Surface Antigen of Babesia Microti

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Babesiosis is a tick‐borne disease that poses a significant threat to animal health worldwide. In addition, climate change and the risk of human‐to‐human transmission through blood transfusion have made babesiosis an emerging disease in humans.
Assia Mouhand, Joana Pissarra, Philippe Barthe, Christian Roumestand, Stéphane Delbecq   +4 more
wiley   +1 more source

Determining the severity of Plasmodium falciparum malaria in Ethiopia

Journal of Infection and Public Health, 2013
Summary: Background: In the majority of health centers in Ethiopia, the severity of falciparum malaria has been determined by parasitemia alone. However, it has been suggested that the use of peripheral infected RBC counts as an indicator of disease ...
Zinaye Tekeste, Meseret Workineh, Beyene Petros   +2 more
doaj  

Mosquito Vectors and the Globalization of Plasmodium falciparum Malaria.

Annual Review of Genetics, 2016
Plasmodium falciparum malaria remains a devastating public health problem. Recent discoveries have shed light on the origin and evolution of Plasmodium parasites and their interactions with their vertebrate and mosquito hosts. P.
Alvaro Molina-Cruz, M. Zilversmit, D. Neafsey, D. Hartl, C. Barillas-Mury   +4 more
semanticscholar   +1 more source

Aminoisothiazolamides, a new class of potent inhibitors of lysyl‐tRNA synthetase

Pest Management Science, EarlyView.
The present work covers a series of novel herbicidal lead structures that possess an aminoisothiazolamide scaffold as a structural key feature. Lysyl‐tRNA synthetase 1 (KRS1) was identified as the biochemical mode‐of‐action. Based on optimized and tailored synthetic approaches, a broader SAR study was carried out delivering some lead structures that ...
David Bernier, David M Barber, Guido Bojack, Birgit Bollenbach‐Wahl, Luke Churchman, Uwe Döller, Tyler Fahrenhorst‐Jones, Jörg Freigang, Elmar Gatzweiler, Claudia Hartfiel, Caroline Hilmi, Yoann Huet, Bernd Laber, Gudrun Lange, Stephanie Lee, Virginie Lempereur, Marc Mosrin, Thomas Müller, China M Payne, Olaf Peters, Luka Posa, Shaun Rees, Anna M Reingruber, Jullien Rey, Jörg Tiebes, Karen Tilmant, Jens Frackenpohl   +26 more
wiley   +1 more source

Parasitaemia and Its Relation to Hematological Parameters and Liver Function among Patients Malaria in Abs, Hajjah, Northwest Yemen

Interdisciplinary Perspectives on Infectious Diseases, 2016
Plasmodium falciparum malaria is the most common infection in Yemen. The present study aims to investigate changes in hematological and hepatic function indices of P. falciparum infected individuals.
Mohamed Al-Salahy, Bushra Shnawa, Gamal Abed, Ahmed Mandour, Ali Al-Ezzi   +4 more
doaj   +1 more source

Plasmodium falciparum parasitaemia and clinical malaria among school children living in a high transmission setting in western Kenya

Malaria Journal, 2016
Malaria among school children is increasingly receiving attention, yet the burden of malaria in this age group is poorly defined. This study presents data on malaria morbidity among school children in Bungoma county, western Kenya.
Stella Kepha, B. Nikolay, F. Nuwaha, C. Mwandawiro, J. Nankabirwa, Juliet Ndibazza, J. Cano, D. Matoke-Muhia, R. Pullan, E. Allen, K. Halliday, S. Brooker   +11 more
semanticscholar   +1 more source

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

Small, EarlyView.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai, Dhwani Rana, Mitali Patel, Neha Bajwa, Rajendra Prasad, Lalitkumar K. Vora   +5 more
wiley   +1 more source

Influence of the number and timing of malaria episodes during pregnancy on prematurity and small-for-gestational-age in an area of low transmission

BMC Medicine, 2017
Background Most evidence on the association between malaria in pregnancy and adverse pregnancy outcomes focuses on falciparum malaria detected at birth.
Kerryn A. Moore, Julie A. Simpson, Jacher Wiladphaingern, Aung Myat Min, Mupawjay Pimanpanarak, Moo Kho Paw, Jathee Raksuansak, Sasithon Pukrittayakamee, Freya J. I. Fowkes, Nicholas J. White, François Nosten, Rose McGready   +11 more
doaj   +1 more source

The pathophysiology of severe falciparum malaria

Parasitology Today, 1986
By the end of the 1940s, the clinical and pathological features of severe falciparum malaria had been well described by military physicians and pathologists working in theatres of war where the disease was endemic. From that time serious efforts were made to discover the pathophysiology of the severe manifestations of malaria because an understanding ...
Phillips, R, Warrell, D
openaire   +3 more sources

Non-falciparum malaria infections in pregnant women in West Africa

Malaria Journal, 2016
Non-Plasmodium falciparum malaria infections are found in many parts of sub-Saharan Africa but little is known about their importance in pregnancy. Blood samples were collected at first antenatal clinic attendance from 2526 women enrolled in a trial of ...
John E. O. Williams, F. Njie, M. Cairns, K. Bojang, S. O. Coulibaly, K. Kayentao, I. Abubakar, Francis Akor, Khalifa Mohammed, Richard Bationo, E. Dabira, Alamissa Soulama, Moussa Djimde, E. Guirou, T. Awine, S. Quaye, J. Ordi, O. Doumbo, A. Hodgson, A. Oduro, P. Magnussen, F. T. ter Kuile, A. Woukeu, P. Milligan, Harry Tagbor, B. Greenwood, D. Chandramohan   +26 more
semanticscholar   +1 more source