Results 111 to 120 of about 258,588 (271)

The role of research in viral disease eradication and elimination programs: Lessons for malaria eradication [PDF]

open access: yes, 2011
By examining the role research has played in eradication or regional elimination initiatives for three viral diseases-smallpox, poliomyelitis, and measles-we derive nine cross-cutting lessons applicable to malaria eradication.
Breman, JG   +6 more
core   +1 more source

Chemotherapeutics for vivax malaria [PDF]

open access: yesMalaria Journal, 2012
Plasmodium vivax imposes significant burdens of morbidity and mortality across the malaria endemic world. Treatment of this infection requires a blood schizontocide against the acute attack and hypnozoitocide against relapses. Chloroquine combined with primaquine has been the therapy of choice for radical cure of vivax malaria since the 1950s ...
openaire   +1 more source

CYP2D6 activity and the risk of recurrence of Plasmodium vivax malaria in the Brazilian Amazon: a prospective cohort study

open access: yesMalaria Journal, 2018
CYP2D6 pathway mediates the activation of primaquine into active metabolite(s) in hepatocytes. CYP2D6 is highly polymorphic, encoding CYP2D6 isoforms with normal, reduced, null or increased activity.
Larissa W Brasil   +8 more
semanticscholar   +1 more source

A Rare Presentation of Babesia‐Associated Splenic Infarction in an Immunocompetent Young Male With Mild Parasitemia

open access: yesCase Reports in Medicine, Volume 2026, Issue 1, 2026.
Babesiosis is a vector‐borne protozoal disease primarily transmitted by the Ixodes scapularis tick, though it can also be transmitted through blood transfusions from infected donors. The illness can be asymptomatic or present with mild flu‐like symptoms.
Jamal A. Anthony   +4 more
wiley   +1 more source

Characterization and gene expression analysis of the cir multi-gene family of plasmodium chabaudi chabaudi (AS) [PDF]

open access: yes, 2012
Background: The pir genes comprise the largest multi-gene family in Plasmodium, with members found in P. vivax, P. knowlesi and the rodent malaria species.
Berriman, Matthew   +11 more
core   +3 more sources

Neglect of Plasmodium vivax malaria

open access: yesTrends in Parasitology, 2007
Plasmodium vivax infects 130-435 million of the 2.6 billion people living at risk of infection. Recent studies suggest that vivax malaria can become lethal in a similar way to severe falciparum malaria. First-line therapies remain unchanged after 50 years.
openaire   +3 more sources

The Hidden Burden of Plasmodium vivax Malaria in Pregnancy in the Amazon: An Observational Study in Northwestern Brazil.

open access: yesAmerican Journal of Tropical Medicine and Hygiene, 2018
We measured the prevalence of malaria in pregnancy and estimated its impact on birth weight and length and maternal hemoglobin in 1,180 women from Juruá Valley, the main malaria hotspot in Brazil.
Anaclara Pincelli   +10 more
semanticscholar   +1 more source

Genetic Diversity of Plasmodium falciparum Merozoite Surface Protein 1 and 2 Genes and Their Allele Association With Malaria Severity, Seasons, and Sex in Bamenda, North West Cameroon

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, Volume 2026, Issue 1, 2026.
Although the number of yearly occurrences of malaria has significantly decreased in recent years, malaria remains one of the major public health issues in Cameroon. A deeper understanding of how the various alleles of the malaria parasite’s genes move in the field between the two sexes and between seasons, as well as knowledge of malaria parasite ...
Che Roland Achungu   +6 more
wiley   +1 more source

Amazonian Plant Natural Products: Perspectives for Discovery of New Antimalarial Drug Leads

open access: yesMolecules, 2013
Plasmodium falciparum and P. vivax malaria parasites are now resistant, or showing signs of resistance, to most drugs used in therapy. Novel chemical entities that exhibit new mechanisms of antiplasmodial action are needed.
Lucio H. Freitas-Junior   +10 more
doaj   +1 more source

Sensitivity and Specificity of Rapid Diagnostic Test with Microscopic Gold Standard to Identify Plasmodium Species [PDF]

open access: yes, 2016
Malaria is a main health problem in islands area which is under developed and isolated. Nation-wide, in 2014 Maluku province was recorded to have Annual Malaria Incident (AMI) value of 30.4%, positive incidents of 13.30%, ABER 3.76%, SPR 21.50%, and ...
Arwati, H. (Heny)   +3 more
core  

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