Results 91 to 100 of about 192,372 (174)

Reduced cytochrome P-450 (CYP) 2D6 activity and Plasmodium vivax malaria risk in Amazonians: A retrospective, population-based cohort study.

PLoS Neglected Tropical Diseases
BackgroundPrimaquine (PQ) is the only widely available drug that eliminates latent hypnozoites, thereby preventing relapses of Plasmodium vivax malaria. Because PQ biotransformation mediated by the cytochrome P-450 (CYP) isoenzyme CYP2D6 is required for ...
Rodrigo M Corder, Maria Carolina S B Puça, Carlos A Prete, Winni A Ladeia, Priscila T Rodrigues, Igor C Johansen, Tais Nobrega de Sousa, Marcelo U Ferreira, Mâncio Lima Cohort Study Working Group   +8 more
doaj   +1 more source

Prolonged fever and exaggerated hypercoagulopathy in malaria vivax relapse and COVID-19 co-infection: a case report. [PDF]

Malar J, 2022
Asmarawati TP, Martani OS, Bramantono B, Arfijanto MV.   +3 more
europepmc   +1 more source

CYP2D6 Allele Frequency in Five Malaria Vivax Endemic Areas From Brazilian Amazon Region. [PDF]

Front Pharmacol, 2021
Salles PF, Perce-da-Silva DS, Rossi AD, Raposo LR, Ramirez Ramirez AD, Pereira Bastos OM, Pratt-Riccio LR, Cassiano GC, Baptista ARS, Cardoso CC, Banic DM, Machado RLD.   +11 more
europepmc   +1 more source

Malaria "diagnosis" and diagnostics in Afghanistan. [PDF]

, 2012
In many malaria-endemic areas, including Afghanistan, overdiagnosis of malaria is common. Even when using parasite-based diagnostic tests prior to treatment, clinicians commonly prescribe antimalarial treatment following negative test results.
Rowland, Mark, Wood, Molly, Kizito, James, Mayan, Ismail, Reynolds, Joanna, Mikhail, Amy, Ahmad, Tamanna, Motahed, Mohibullah, Anwari, Nadia, Karimullah, Karimullah, Baktash, Sayed Habib, Leslie, Toby, Chandler, Clare, Hazansai, Anwar   +13 more
core   +1 more source

Severe disease in children hospitalized with a diagnosis of Plasmodium vivax in south-eastern Pakistan

Malaria Journal, 2012
Background Infection by Plasmodium vivax has been considered rarely threatening to life, but recent studies challenge this notion. This study documented the frequency and character of severe illness in paediatric patients admitted to a hospital in south ...
Shaikh Salma, Memon Hafeezullah, Iohano Bhagchand, Shaikh Amna, Ahmed Imran, Baird J   +5 more
doaj   +1 more source

Probing the Clinical, Laboratory, and Sociodemographic Factors Associated with Malaria: A Case-Control Study

Journal of Pharmacy and Bioallied Sciences
Background: The National Malaria Elimination Program (NMEP) has helped reduce the mortality from malaria in India, and there are alarmingly high mortality rates from anemia in certain geographical regions.
Ritesh Upadhyay, Annasaheb J. Dhumale, Chanchlesh Dehariya, Renu Waghmare, Amit Rangari   +4 more
doaj   +1 more source

The role of cytokines in Plasmodium vivax malaria

Memorias do Instituto Oswaldo Cruz, 1992
The cytokine tumor necrosis factor and other as yet unidentified factor(s) which together mediate the killing of intraerythrocytic malaria parasites are transiently elevated in sera during paroxysms in human Plasmodium vivax infections in non-immunes ...
K. N. Mendis, R. Carter
doaj   +1 more source

Interaction of malaria with a common form of severe thalassemia in an Asian population.

, 2009
In many Asian populations, the commonest form of severe thalassemia results from the coinheritance of HbE and beta thalassemia. The management of this disease is particularly difficult because of its extreme clinical diversity; although some genetic and ...
Peto, TE, Olivieri, NF, Stephen Allen, O'Donnell, A, Allen, SJ, Weatherall, DJ, Samaranayake, R, Olivieri, Nancy F, Cook, J, Premawardhena, A, Corran, PH, Arambepola, M, Fisher, CA, Peto, TEA   +13 more
core   +1 more source

A research agenda for malaria eradication: basic science and enabling technologies. [PDF]

, 2011
Today's malaria control efforts are limited by our incomplete understanding of the biology of Plasmodium and of the complex relationships between human populations and the multiple species of mosquito and parasite.
McGovern, V., Duraisingh, M., Okumu, F., Dinglasan, R, Llinas, M., Kramarik, J., Baum, J., Christophides, G., malERA Consultative Group on Basic Science and Enabling Technologies, Bassat, Q., Djimde, A., Mota, M., Billker, O, Lacerda, M., de Koning-Ward, T., Rasgon, J., Lim, P., Laufer, M., Bousema, T., Bousema, T, malERA Consultative Group on Basic Science and Enabling Technolo, Billker, O., McGovern, V, Sinden, R., Mota, MM, Happi, C., Dzinjalamala, F., Heussler, Volker, Sharma, P., Mueller, I., Serazin, A., Mueller, I, Bogyo, M., Wirth, D., null null, Gilberger, T., Sinden, R, Amino, R., Martinez-Barnetche, J., Baum, J, Deitsch, K., Dinglasan, R.   +41 more
core   +2 more sources

Comparative assessment of clinic-laboratory profile of different species of severe malaria in a tertiary care institute in southern India

Journal of Vector Borne Diseases, 2019
Background & objectives: Majority of the studies on severe malaria in India have concentrated on falciparum and have been done in northern part.
Thomas Kuncheria, Nithyananda K Chowta, Deepak Madi, Mukta N Chowta, A Basavaprabhu   +4 more
doaj