Results 91 to 100 of about 53,747 (224)
Estimating the numbers of malaria infections in blood samples using high-resolution genotyping data [PDF]
, 2012 People living in endemic areas often habour several malaria infections at once. High-resolution genotyping can distinguish between infections by detecting the presence of different alleles at a polymorphic locus.
Amanda Ross +8 more
core +3 more sources
Tropical Medicine &International Health, Volume 31, Issue 3, Page 254-273, March 2026.ABSTRACT Background Malaria is a major public health issue in East Africa, leading to widespread illness and fatalities, especially among vulnerable populations such as children under 5 years of age and pregnant women. Artemisinin‐based combination therapies (ACTs) are the primary treatment modality; however, their efficacy is undermined by the ...
Yesuneh Tefera Mekasha +5 more
wiley +1 more source
Neglect of Plasmodium vivax malaria
Trends in Parasitology, 2007 Plasmodium vivax infects 130-435 million of the 2.6 billion people living at risk of infection. Recent studies suggest that vivax malaria can become lethal in a similar way to severe falciparum malaria. First-line therapies remain unchanged after 50 years.
openaire +3 more sources
Malaria Journal, 2012 Microvascular sequestration of Plasmodium falciparum underlies cerebral malaria. Despite suggestive ex vivo evidence, this phenomenon has not been convincingly demonstrated in coma complicating Plasmodium vivax malaria.
Manning Laurens +7 more
doaj +1 more source
ChemMedChem, Volume 21, Issue 3, 12 February 2026.A random forest machine learning model was used in combination with molecular docking to predict activity of small molecule kinase inhibitors against two crucial antimalarial targets, namely hemozoin crystallization and Plasmodium falciparum protein kinase G. Derazantinib shows most promise as a dual inhibitor.
Jessica L. Thibaud +7 more
wiley +1 more source
Amazonian Plant Natural Products: Perspectives for Discovery of New Antimalarial Drug Leads
Molecules, 2013 Plasmodium falciparum and P. vivax malaria parasites are now resistant, or showing signs of resistance, to most drugs used in therapy. Novel chemical entities that exhibit new mechanisms of antiplasmodial action are needed.
Lucio H. Freitas-Junior +10 more
doaj +1 more source
Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.Bti BR101 exhibits strong larvicidal activity against Anopheles larvae spp., with dose‐dependent mortality and LC50 of 3.13 µg/mL. Bti increases ROS, lipid and protein oxidation, and activates antioxidant enzymes (SOD, CAT, GPx) and detoxification pathways (MFO and esterases), indicating moderate oxidative stress.
Izabel Cristina de Oliveira Bentes +14 more
wiley +1 more source
Complicated vivax malaria, an often underestimated condition - Case Report
Journal of Family and Community Medicine, 2015 Malaria is a vector-borne disease that is endemic in 91 countries. South East Asia is the second most affected region in the world, with India carrying the highest burden of the disease.
Arumugam Aashish, Gopi Manigandan
doaj +1 more source
BIO Web of Conferences, 2020 Regency of Tanah Bumbu has an annual parasitic incidence rate (API) 0.82 and in 2016 the number of API decreased to 0.48. However, there are malaria cases that still occur in the 5 (five) locations of the workplace of the public health center with the ...
Rahayu Nita +2 more
doaj +1 more source
Clinical Case Reports, Volume 14, Issue 2, February 2026.ABSTRACT In endemic areas, acute undifferentiated febrile illness has a wide differential with overlapping features that can lead to misdiagnosis. Although triple co‐infection with scrub typhus, dengue, and leptospirosis is extremely rare, high clinical suspicion and early detection are vital to avoid delayed treatment, multi‐organ dysfunction, and ...
Sulav Kumar Jha +5 more
wiley +1 more source