Results 81 to 90 of about 192,372 (174)

Duffy negative antigen is no longer a barrier to Plasmodium vivax--molecular evidences from the African West Coast (Angola and Equatorial Guinea). [PDF]

open access: yes, 2011
BACKGROUND: Plasmodium vivax shows a small prevalence in West and Central Africa due to the high prevalence of Duffy negative people. However, Duffy negative individuals infected with P.
Ochando, Jordi   +33 more
core   +2 more sources

Effects of Drug Resistance on the Global Spread of Malaria: A Systematic Literature Review

open access: yesHealth Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Malaria remains a major health crisis in tropical regions, with Sub‐Saharan Africa bearing the heaviest burden. While insecticide‐treated nets and artemisinin‐based combination therapies (ACTs) have reduced cases, emerging parasite resistance to artemisinin threatens these gains. This review synthesizes evidence on how drug
Ashenafi Woldemichael Woime
wiley   +1 more source

Complicated vivax malaria, an often underestimated condition - Case Report

open access: yesJournal of Family and Community Medicine, 2015
Malaria is a vector-borne disease that is endemic in 91 countries. South East Asia is the second most affected region in the world, with India carrying the highest burden of the disease.
Arumugam Aashish, Gopi Manigandan
doaj   +1 more source

ama1 genes of sympatric Plasmodium vivax and P. falciparum from Venezuela differ significantly in genetic diversity and recombination frequency. [PDF]

open access: yes, 2008
BACKGROUND: We present the first population genetic analysis of homologous loci from two sympatric human malaria parasite populations sharing the same human hosts, using full-length sequences of ama1 genes from Plasmodium vivax and P.
Sutherland, Colin J   +6 more
core   +3 more sources

Deconstruction of Aspartic Protease Inhibitors Enables Fragment‐Based Discovery of Plasmepsin V Inhibitors

open access: yesChemMedChem, Volume 21, Issue 15, 14 August 2026.
A structure‐informed, fragment‐based approach was used to identify non‐peptidomimetic inhibitors of plasmepsin V. Pyrrolidine, piperidine, and piperazine containing fragments showed activity in a FRET assay. The optimization of the pyrrolidine scaffold resulted in N‐sulfonamide analogs with potency up to ~10 µM, establishing a promising scaffold for ...
Marija Skvorcova   +4 more
wiley   +1 more source

A histopathologic study of fatal paediatric cerebral malaria caused by mixed Plasmodium falciparum/Plasmodium vivax infections

open access: yesMalaria Journal, 2012
Microvascular sequestration of Plasmodium falciparum underlies cerebral malaria. Despite suggestive ex vivo evidence, this phenomenon has not been convincingly demonstrated in coma complicating Plasmodium vivax malaria.
Manning Laurens   +7 more
doaj   +1 more source

Anti-Inflammatory Cytokines Predominate in Acute Human Plasmodium knowlesi Infections. [PDF]

open access: yes, 2011
Plasmodium knowlesi has entered the human population of Southeast Asia. Naturally acquired knowlesi malaria is newly described with relatively little available data, including data on the host response to infection.
Parker-Williams, J   +28 more
core   +2 more sources

Acute Febrile Illness With Triple Co‐Infection: A Case Report on the Diagnostic Challenges of Overlapping Febrile Illnesses

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT A 35‐year‐old female presented with 5 days of fever, fatigue, and myalgia during the post‐monsoon season at Damak Hospital, Jhapa, Nepal. Clinical examination revealed fever (102.7°F), tachycardia (110 bpm), and crackles in the right lower lung field.
Santosh Basyal   +7 more
wiley   +1 more source

Amazonian Plant Natural Products: Perspectives for Discovery of New Antimalarial Drug Leads

open access: yesMolecules, 2013
Plasmodium falciparum and P. vivax malaria parasites are now resistant, or showing signs of resistance, to most drugs used in therapy. Novel chemical entities that exhibit new mechanisms of antiplasmodial action are needed.
Lucio H. Freitas-Junior   +10 more
doaj   +1 more source

Suppression of Plasmodium falciparum by serum collected from a case of Plasmodium vivax infection [PDF]

open access: yes, 2008
Background: It has frequently been reported that Plasmodium vivax suppressed Plasmodium falciparum and ameliorated disease severity in patients infected with these two species simultaneously.
Kimura-Sato, M   +39 more
core   +1 more source

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