Blood-stage parasitaemia and age determine Plasmodium falciparum and P. vivax gametocytaemia in Papua New Guinea [PDF]
A better understanding of human-to-mosquito transmission is crucial to control malaria. In order to assess factors associated with gametocyte carriage, 2083 samples were collected in a cross-sectional survey in Papua New Guinea.
Ingrid Felger (92160) +47 more
core +2 more sources
Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva +10 more
wiley +1 more source
Plasmodium vivax malaria is a neglected tropical disease, despite being more geographically widespread than any other form of malaria. The documentation of P.
Daniel Kepple +5 more
doaj +1 more source
Plasmodium vivax diversity and population structure across four continents [PDF]
Plasmodium vivax is the geographically most widespread human malaria parasite. To analyze patterns of microsatellite diversity and population structure across countries of different transmission intensity, genotyping data from 11 microsatellite markers ...
Barnadas, Céline +84 more
core +2 more sources
A Framework for Cross‐National Collective Intelligence Facilitation
Systems Research and Behavioral Science, EarlyView.
Owen M. Harney +3 more
wiley +1 more source
ABSTRACT Aim This study examines the predictive power of constructs from the health belief model (HBM) and theory of planned behaviour (TPB) in explaining malaria vaccine acceptance in Ghana in the post‐COVID‐19 era, while also assessing the reliability of these constructs within this context.
Michael Sarfo +2 more
wiley +1 more source
Analysis of Polymorphisms in the Merozoite Surface Protein-3? Gene and Two Microsatellite Loci in Sri Lankan Plasmodium vivax: Evidence of Population Substructure in Sri Lanka. [PDF]
: Abstract. The geographical distribution of genetic variation in Plasmodium vivax samples (N = 386) from nine districts across Sri Lanka is described using three markers; the P. vivax merozoite surface protein-3?
Alifrangis, M +8 more
core +4 more sources
Strategies for understanding and reducing the Plasmodium vivax and Plasmodium ovale hypnozoite reservoir in Papua New Guinean children : a randomised placebo-controlled trial and mathematical model [PDF]
The undetectable hypnozoite reservoir for relapsing Plasmodium vivax and P. ovale malarias presents a major challenge for malaria control and elimination in endemic countries.
Bassat Orellana, Quique +82 more
core +1 more source
Peptide‐enabled nanoplatforms offer multifunctional strategies for the treatment and diagnosis of malaria and leishmaniasis. Liposomal, polymeric, and metallic nanocarriers, together with cell‐penetrating peptides and parasite‐derived mimotopes, can improve targeted drug delivery, stability, bioavailability, and intracellular localization.
Christian S. Carnero Canales +7 more
wiley +1 more source
A research agenda for malaria eradication: diagnoses and diagnostics. [PDF]
Many of malaria's signs and symptoms are indistinguishable from those of other febrile diseases. Detection of the presence of Plasmodium parasites is essential, therefore, to guide case management.
The maIera Consultative Group on Diagnoses and Diagnostics, +2 more
core +1 more source

