Results 41 to 50 of about 53,747 (224)

Strategies for Understanding and Reducing the Plasmodium vivax and Plasmodium ovale Hypnozoite Reservoir in Papua New Guinean Children: A Randomised Placebo-Controlled Trial and Mathematical Model [PDF]

, 2015
The undetectable hypnozoite reservoir for relapsing Plasmodium vivax and P. ovale malarias presents a major challenge for malaria control and elimination in endemic countries.
Bassat, Quique, Betuela, Inoni, Brewster, Jessica, Felger, Ingrid, Hofmann, Natalie E., Karl, Stephan, Kinboro, Benson, Kiniboro, Benson, Li Wai Suen, Connie S. N., Lorry, Lina, Mueller, Ivo, Robinson, Leanne J., Samol, Lornah, Schofield, Louis, Siba, Peter M., Silkey, Mariabeth, Tarongka, Nandao, Waltmann, Andreea, Wampfler, Rahel, White, Michael T.   +19 more
core   +7 more sources

The pathophysiology of vivax malaria

Trends in Parasitology, 2009
Long considered a benign infection, Plasmodium vivax is now recognized as a cause of severe and fatal malaria, despite its low parasite biomass, the increased deformability of vivax-infected red blood cells and an apparent paucity of parasite sequestration.
Anstey, N, Russell, B, Yeo, T, Price, R
openaire   +3 more sources

Parasite biomass-related inflammation, endothelial activation, microvascular dysfunction and disease severity in vivax malaria.

PLoS Pathogens, 2015
Plasmodium vivax can cause severe malaria, however its pathogenesis is poorly understood. In contrast to P. falciparum, circulating vivax parasitemia is low, with minimal apparent sequestration in endothelium-lined microvasculature, and pathogenesis ...
Bridget E Barber, Timothy William, Matthew J Grigg, Uma Parameswaran, Kim A Piera, Ric N Price, Tsin W Yeo, Nicholas M Anstey   +7 more
doaj   +1 more source

Severe thrombocytopaenia in patients with vivax malaria compared to falciparum malaria: a systematic review and meta-analysis

Infectious Diseases of Poverty, 2018
Background Plasmodium vivax is the most geographically widespread species among human malaria parasites. Immunopathological studies have shown that platelets are an important component of the host innate immune response against malaria infections.
Cho Naing, Maxine A. Whittaker
doaj   +1 more source

Complicated Plasmodium vivax infection with malarial hepatopathy and splenic abscess

BLDE University Journal of Health Sciences, 2019
Malaria is a serious health burden in the tropical countries. Jaundice is a known manifestation of complicated falciparum malaria but is unusual with Plasmodium vivax infection. Only a few cases of vivax malarial hepatopathy have been reported till date.
Priya Bansal, Ankit Gupta, Ravi Meena
doaj   +1 more source

Clinical and parasitological response to oral chloroquine and primaquine in uncomplicated human Plasmodium knowlesi infections [PDF]

, 2013
Background: Plasmodium knowlesi is a cause of symptomatic and potentially fatal infections in humans. There are no studies assessing the detailed parasitological response to treatment of knowlesi malaria infections in man and whether antimalarial ...
Cox Singh, Janet, Daneshvar, Cyrus, Davis, Timothy M. E., Divis, Paul C. S., Rafa'ee, Mohammad Z., Singh, Balbir, Zakaria, Siti K.   +6 more
core   +1 more source

Severe Plasmodium vivax Malaria in Pakistan

Emerging Infectious Diseases, 2013
To compare the severity of Plasmodium vivax malaria with that of P. falciparum malaria, we conducted a retrospective cross-sectional study of 356 adults hospitalized with malaria (2009–2011) in Pakistan. P. vivax and P.
Ali Bin Sarwar Zubairi, Sobia Nizami, Afsheen Raza, Vikram Mehraj, Anita Fazal Rasheed, Najia Karim Ghanchi, Zahra Nur Khaled, M. Asim Beg   +7 more
doaj   +1 more source

Malaria in Nonimmune Travelers [PDF]

, 1994
Background: With the current increase of international travel to tropical endemic areas, the incidence of malaria being imported into nonendemic countries has increased significantly.
Jelinek, Thomas, Löscher, Thomas, Nothdurft, H. D.   +2 more
core   +1 more source

KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro. [PDF]

, 2014
Preventing relapses of Plasmodium vivax malaria through a radical cure depends on use of the 8-aminoquinoline primaquine, which is associated with safety and compliance issues.
Borboa, Rachel, Campo, Brice, Chatterjee, Arnab K, Chen, Zhong, Diagana, Thierry T, Gagaring, Kerstin, Glynne, Richard J, Klooster, Els J, Kocken, Clemens HM, Kuhen, Kelli, Leroy, Didier, Luty, Adrian, McNamara, Case W, Nagle, Advait, Plouffe, David M, Remarque, Edmond J, Roland, Jason, Sauerwein, Robert, Thomas, Alan W, van Amsterdam, Sandra M, van den Berg, Alexander, van Gemert, Geert-Jan, Voorberg-van der Wel, Annemarie, Winzeler, Elizabeth A, Yeung, Bryan KS, Zeeman, Anne-Marie   +25 more
core   +1 more source

Crystal structure of Plasmodium vivax macrophage migration inhibitory factor

Acta Crystallographica Section F, EarlyView.
The production, crystallization and 1.8 Å resolution crystal structure of macrophage migratory inhibitory factor from P. vivax are reported.Plasmodium vivax is a major cause of malaria globally and has recently been transmitted locally in the USA. P. vivax produces homologs of host proteins, including cytokines such as macrophage migration inhibitory ...
Aryana Nair, Matthew Lin, Arav Srivastava, Lijun Liu, Anne Cooper, Kevin Battaile, Elizabeth Harmon, Peter J. Myler, Bart L. Staker, Scott Lovell, Graham Chakafana, Oluwatoyin A. Asojo   +11 more
wiley   +1 more source