Results 131 to 140 of about 79,327 (229)

Nonclassical MHC‐I Molecules: Emerging Therapeutic Targets in Next‐Generation Immunotherapy

open access: yesMedComm, Volume 7, Issue 5, May 2026.
Immunotherapies dependent on classical MHC‐I molecules face significant challenges, including extreme polymorphism and frequent downregulation in pathological conditions. This review discusses how nonclassical MHC‐I molecules (HLA‐E, HLA‐F, HLA‐G, CD1, MR1) may potentially circumvent these limitations through restricted genetic diversity, stable ...
Wanlin He, Andrew J. McMichael
wiley   +1 more source

Efficacy and immunogenicity of RTS,S/AS01 and R21/Matrix-M malaria vaccines: - Systematic review and meta-analysis

open access: yesJournal of Infection and Public Health
Background: Malaria is one of the most concerning issues of public health. Despite efforts in vector control and chemoprevention, it continues to remain a burden, and hence, a vaccine for malaria has the potential to reduce the overall parasite reservoir.
Hafsah Asjad   +6 more
doaj   +1 more source

Experiences of Nurses Caring for Patients With COVID‐19: A Descriptive Phenomenological Study

open access: yesNursing Open, Volume 13, Issue 5, May 2026.
ABSTRACT Aim The current study aimed to explore the lived experiences of nurses providing care to patients with COVID‐19. Design A descriptive phenomenological approach. Methods The study was conducted among 9 purposively sampled nurses who worked in the COVID‐19 isolation centers of Kumasi South Hospital and Manhyia District Hospital, Kumasi. With the
Jerry Armah   +8 more
wiley   +1 more source

Wise Blood: The Principle of Overcoming in Disease and Immunity (Part 1) [PDF]

open access: yes, 2020
The immune system is an intelligently made system designed for interaction with microbes even in a perfect world; it is more than a defense. However, in a post-fall world, it is primarily a body’s defense system.
Gillen, Alan L., Huy, Keoprommony
core   +1 more source

Robust Bioconjugated Antigens Induce Immune Responses Preventing Malaria Infection and its Transmission

open access: yesSmall, Volume 22, Issue 28, 18 May 2026.
Engineered malaria antigens enable in vivo bioconjugation to submicron biopolymer particles in E. coli. Two antigens are co‐tethered at high density and defined stoichiometry. The resulting thermostable particles elicit strong, durable antibody and T‐cell responses, conferring robust protection and blocking mosquito transmission.
Nivethika Sivakumaran   +10 more
wiley   +1 more source

Efficacy of phase 3 trial of RTS, S/AS01 malaria vaccine: The need for an alternative development plan

open access: yesHuman Vaccines & Immunotherapeutics, 2017
Although vaccines would be the ideal tool for control, prevention, elimination, and eradication of many infectious diseases, developing of parasites vaccines such as malaria vaccine is very complex.
Shima Mahmoudi, Hossein Keshavarz
doaj   +1 more source

Knowledge, Attitude and Practice of the Community Toward Pet Contact‐Related Zoonoses in Mekelle, Tigray, Ethiopia

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
The study titled ‘Knowledge, Attitude, and Practice of the Community toward pet contact–related zoonoses in Mekelle, Tigray, Ethiopia’ found that 59.5% of pet owners had good knowledge of zoonotic diseases and 74.2% showed positive attitudes, but only 43.3% practiced proper prevention.
Haftay Teklay   +2 more
wiley   +1 more source

Glanders: Past, Present and Future of a Neglected Zoonosis as a Threat in Veterinary and Human Health

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
This review displays a comprehensive overview of glanders, including aetiology, epidemiology, pathogenesis, diagnosis, control strategies and ongoing eradication programs. It has also reviewed differential diagnosis and treatment both in animals and humans as well as organism's antimicrobial properties.
Yahya Kanani   +2 more
wiley   +1 more source

The Human Threat From West Nile Virus and Usutu Virus in a Changing Climate

open access: yesAPMIS, Volume 134, Issue 5, May 2026.
ABSTRACT In recent years, the closely related arboviruses West Nile virus (WNV) and Usutu virus (USUV) have spread farther north in Europe. The viruses often co‐circulate and are maintained in a natural cycle between ornithophilic mosquitoes and birds.
Ingrid Pontoppidan Føh   +6 more
wiley   +1 more source

Conducting Controlled human infection model studies in India is an ethical obligation [PDF]

open access: yes, 2018
Weighing competing obligations and achieving the “greatest balance” of right over wrong guides an individual, an agency or a country in determining what ought to be done in an ethically challenging situation.
Dholakia, S. Y., Dholakia, Saumil
core  

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