Results 1 to 10 of about 5,753 (147)

Anti-NMDAR encephalitis following malaria: expanding the spectrum of post−malarial neurological syndromes [PDF]

Frontiers in Immunology
BackgroundAnti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is the most common form of autoimmune encephalitis (AIE), often triggered by viral infections or tumors.
Shuwen Deng, Shuwen Deng, Wenlong Wang, Wei Lu, Shige Wang, Shige Wang   +5 more
doaj   +2 more sources

Diagnostic value of full blood count derived systemic inflammatory biomarkers in malaria infection [PDF]

Practical Laboratory Medicine
Background: Malaria remains a public health issue. Its associated inflammatory responses can easily shift from benefit to detriment, making early detection of malarial inflammation crucial.
Joseph Boachie, Derrick Ahiable, Leticia Awonbiistemi Ajabuin, Richard Amissah, Abigail Asmah-Brown, Safianu Apalebilah, Ama Gyasiwaah Owusu-Poku, Henrietta Eshun, Patrick Adu, Joel Karikari Nyarkoh   +9 more
doaj   +2 more sources

Stroke incidence, presentation, and outcomes in malaria: a review of current evidence [PDF]

Malaria Journal
Malaria, a global health challenge, remains a leading cause of morbidity and mortality, particularly in sub-Saharan Africa, Southeast Asia, and South America.
Nicholas Aderinto, Israel Charles Abraham, Gbolahan Olatunji, Emmanuel Kokori, Adetola Emmanuel Babalola, Aditya Gaur, Emmanuel Adeoba Babawale, Olufemi Akinmeji, Ayobami Oyetunji Alabi   +8 more
doaj   +2 more sources

THROMBOCYTOPENIA AND ELEVATED ALANINE AMINOTRANSFERASE LEVELS IN MALARIA PATIENTS

Pakistan Armed Forces Medical Journal, 2021
Objective: To study thrombocytopenia and elevated ALT levels in malaria patients reporting to Pak Med Level II+ Hospital XII and XIII, UN Mission Liberia, West Africa. Study Design: Cross sectional study. Place and Duration of Study: Departments of
Sayed Tanveer Abbas Gilani, Amjad Khan, Tariq Ali Khan, Muhammad Farooq   +3 more
doaj   +1 more source

Anti-Malarial and Anti-Lipid Peroxidation Activities of Deferiprone-Resveratrol Hybrid in Plasmodium berghei-Infected Mice

Biology, 2021
Iron is essential for all organisms including fast-dividing malarial parasites. Inversely, iron chelators can inhibit parasite growth through the inhibition of DNA synthesis and can ameliorate oxidative cell damage.
Hataichanok Chuljerm, Supawadee Maneekesorn, Voravuth Somsak, Yongmin Ma, Somdet Srichairatanakool, Pimpisid Koonyosying   +5 more
doaj   +1 more source

Anti-malarial activity of HCl salt of SKM13 (SKM13-2HCl)

International Journal for Parasitology: Drugs and Drug Resistance, 2022
Malaria is among the most devastating and widespread tropical parasitic diseases in developing countries. To prevent a potential public health emergency, there is an urgent need for new antimalarial drugs, with single-dose cures, broad therapeutic ...
Thuy-Tien Thi Trinh, Su-Yeon Yun, Gum-Ju Bae, Kwonmo Moon, Hyelee Hong, Tae Hui Eum, Young-ah Kim, Soon-Ai Kim, Hyun Park, Hak Sung Kim, Seon-Ju Yeo   +10 more
doaj   +1 more source

COMPARISON OF IMMUNOCHROMATOGRAPHY AND MICROSCOPIC FILM METHOD FOR THE DIAGNOSIS OF MALARIA IN LIBERIA

Pakistan Armed Forces Medical Journal, 2020
Objective: To compare immunochromatography and microscopic film method for the diagnosis of malaria in patients reporting to United Nations deployed hospital in Liberia. Study Design: Diagnostic accuracy study.
Syed Tanveer Abbas Gilani, Amjad Khan, Muhammad Ijaz, Muhammad Farooq   +3 more
doaj   +4 more sources

Anti-malarial activity of traditional Kampo medicine Coptis rhizome extract and its major active compounds

Malaria Journal, 2020
Background Herbal medicine has been a rich source of new drugs exemplified by quinine and artemisinin. In this study, a variety of Japanese traditional herbal medicine (‘Kampo’) were examined for their potential anti-malarial activities.
Awet Alem Teklemichael, Shusaku Mizukami, Kazufumi Toume, Farhana Mosaddeque, Mohamed Gomaa Kamel, Osamu Kaneko, Katsuko Komatsu, Juntra Karbwang, Nguyen Tien Huy, Kenji Hirayama   +9 more
doaj   +1 more source

Development of a human malaria-on-a-chip disease model for drug efficacy and off-target toxicity evaluation

Scientific Reports, 2023
A functional, multi-organ, serum-free system was developed for the culture of P. falciparum in an attempt to establish innovative platforms for therapeutic drug development.
Michael J. Rupar, Trevor Sasserath, Ethan Smith, Brandon Comiter, Narasimhan Sriram, Christopher J. Long, Christopher W. McAleer, James J. Hickman   +7 more
doaj   +1 more source

Dinuclear and mononuclear metal(II) polypyridyl complexes against drug-sensitive and drug-resistant Plasmodium falciparum and their mode of action

Malaria Journal, 2022
Background Malaria remains one of the most virulent and deadliest parasitic disease in the world, particularly in Africa and Southeast Asia. Widespread occurrence of artemisinin-resistant Plasmodium falciparum strains from the Greater Mekong Subregion is
Jing Wei Lai, Mohd Jamil Maah, Kong Wai Tan, Rozie Sarip, Yvonne Ai Lian Lim, Rakesh Ganguly, Loke Tim Khaw, Chew Hee Ng   +7 more
doaj   +1 more source