Results 71 to 80 of about 5,753 (147)
Multifaceted Roles of Chloroquines in Gastrointestinal Disorders and Beyond
Chloroquine (CQ) and hydroxychloroquine (HCQ) modulate lysosomal activity and autophagy, suppressing gastrointestinal inflammation and reshaping pathogenic microbiota. These mechanisms alleviate inflammatory bowel disease, inhibit associated tumor growth, and provide benefits in certain autoimmune and viral conditions.
Sihyun Jeong +3 more
wiley +1 more source
We present a unified benchmark of fourteen attention mechanisms across multiple CNN backbones and diverse medical imaging datasets, revealing that attention effectiveness is highly scenario‐ and architecture‐dependent. The study provides practical, evidence‐based guidance for selecting attention designs that yield reliable performance gains in medical ...
Nujhat Raisa Arpa +5 more
wiley +1 more source
ABSTRACT Background and Aims Anemia in pregnancy (AiP) remains a public health concern in Ghana. The Bono East Region is known for a variety of maternal morbidities, yet the association between inadequate intake of iron‐rich foods and AiP remains underexplored.
Dennis Bardoe +5 more
wiley +1 more source
ABSTRACT Background and Aims Malaria and anemia remain major public health challenges contributing substantially to morbidity and mortality among children under 5 years in sub‐Saharan Africa (SSA). Although conventional regression analyses have reported a significant association between malaria infection and anemia, these approaches often inadequately ...
Edson Mwebesa +9 more
wiley +1 more source
ABSTRACT Background Malaria is a critical public health concern in Nigeria with the country bearing an uneven burden of the disease. In Nigeria, malaria is one of the main causes of child mortality and despite all efforts to reduce malaria mortality rates, the disease remains a major concern, notably among children under‐fives.
Justice Moses K. Aheto +23 more
wiley +1 more source
Severe Malaria in Neonates Masquerading as Septicaemia
Background: Malaria was once thought to be rare in the neonatal period, especially in neonates of semi-immune mothers in holoendemic areas. As a result, ill neonates admitted to newborn special care units are often presumed to have neonatal sepsis ...
Ojukwu JU , Ezeonu CT , Ogbu CN
doaj
De novo or Salvage? Nucleotide Availability as a Driver of Bacterial Adaptation and Virulence
Bacterial pathogens survive in different host environments by switching between making nucleotides by de novo synthesis and scavenging them from the host. This flexibility supports growth and virulence making nucleotide metabolism an attractive therapeutic target.
Riya Joshi +2 more
wiley +1 more source
ABSTRACT Malaria remains a major global health challenge, with an urgent need for new therapies to combat the evolving resistance to anti‐malarial treatments. Physiologically‐based pharmacokinetic (PBPK) modeling offers a promising approach to accurately predict PK, optimize dosing strategies, reduce development time and cost, and de‐risk the ...
Junjie Ding +3 more
wiley +1 more source
Searching for the beasts in the archive as methodological praxis
This article offers searching for the beasts in the archive as a methodological tool available to researchers invested in both anticolonialism and antianthropocentrism. By focusing on three basic units of reference—categories, histories, and borders—the article shows how searching for the beasts unsettles some taken‐for‐granted assumptions that ...
Senel Wanniarachchi
wiley +1 more source
Improving Malaria Parasite Gene Flow Inference Under Sparse Spatial Sampling
ABSTRACT Estimating malaria parasite migration is crucial for informing elimination strategies, particularly by identifying regions with higher parasite migration that may serve as transmission sources and intervention targets. Methods that infer spatial variations in gene flow from georeferenced genetic data, including Estimated Effective Migration ...
Yao Li +4 more
wiley +1 more source

