Results 141 to 150 of about 369,761 (340)
Protective Role for Itaconate During Inhaled Allergen Challenge
Allergy, EarlyView.Itaconate levels decrease in sputum following allergen inhalation in mild asthmatics, suggesting a dynamic metabolic response to airway challenge. Genetic deletion of Acod1 in mice did not alter airway inflammation or remodelling in response to chronic HDM exposure.
Gesa J. Albers +16 more
wiley +1 more source
A reappraisal of some structural features of bovine heart malate dehydrogenase [PDF]
, 1968 Elizabeth Heyde, Stanley Ainsworth
openalex +1 more source
European Journal of Clinical Investigation, EarlyView.We investigated measures of mitochondrial function in certain types of blood cells and metabolism in 65 children, 5–10 years old. Compared to children of normal weight (n = 20), children with overweight/obesity (n = 28) and especially those with insulin resistance (n = 17), differed in how their cells produced energy.
Eugenia Carvalho +5 more
wiley +1 more source
Frontiers in Neurology, 2019 Mitochondria constitute a central role in brain energy metabolism, and play a pivotal role in the development of secondary pathophysiology and subsequent neuronal cell death following traumatic brain injury (TBI).
Jignesh D. Pandya +7 more
doaj +1 more source
Combating muscle atrophy: emerging therapeutic targets that are fiber‐type‐specific
The FEBS Journal, EarlyView.Inflammation, denervation or decreased insulin signaling activate proteolysis and cause muscle wasting. Pathological conditions like obesity and DMD can also exacerbate atrophy via PGD2–RhoA–ROCK2 signaling. In contrast, exercise, dietary interventions, and pharmacological agents can activate Ca2+/calcineurin–NFAT and AMPK–PGC‐1α–MEF pathways ...
Samrat Chakraborty +2 more
wiley +1 more source
Journal of Lipid Research, 1973 Cyclopropenoid fatty acids in the diet of rainbow trout caused significant reductions in liver protein and activity of glucose-6-phosphate dehydrogenase, NADP-linked isocitrate dehydrogenase, lactate dehydrogenase, and malate dehydrogenase.
S.L. Taylor, M.W. Montgomery, D.J. Lee
doaj +1 more source
The FEBS Journal, EarlyView.Expression of the LEA‐K peptide in E. coli BL21 (DE3) improved bacterial viability under acidic stress (pH4), suggesting a protective function. RNA‐sequencing of LEA‐K‐expressing vs. non‐expressing cells revealed 283 differentially expressed genes (DEGs). In silico docking linked LEA‐K to two‐component systems (TCS) proteins (Rcs, BtsS/R, and EnvZ/OmpR)
Khaled Metwally, Shinya Ikeno
wiley +1 more source
Cryptic CAM photosynthesis in Joshua tree (Yucca brevifolia, Y. jaegeriana)
New Phytologist, EarlyView.Summary Joshua trees are long‐lived perennial monocots native to the Mojave Desert in North America. Composed of two species, Yucca brevifolia and Y. jaegeriana (Asparagaceae), Joshua trees are imperiled by climate change, with decreases in suitable habitat predicted under future climate change scenarios.
Karolina Heyduk +16 more
wiley +1 more source
, 2006 Buchnera aphidicola, the primary endosymbiont of aphids, has undergone important genomic and biochemical changes as an adaptation to intracellular life.
Gil, Rosario +4 more
core +1 more source
Guard cell starch and malate metabolism facilitate stomatal opening in response to low CO2
New Phytologist, EarlyView.Summary Guard cells adjust turgor to regulate stomatal aperture, integrating ion transport with metabolic adjustments. The effect of reduced CO2 on stomatal movement, expected under enhanced photosynthesis, remains largely unexplored. We exposed Arabidopsis thaliana plants to low CO2 before light onset and analyzed guard cell starch turnover, malate ...
Fernanda A. L. Silva‐Alvim +3 more
wiley +1 more source