Results 111 to 120 of about 167,858 (299)

AI‐Driven Cancer Multi‐Omics: A Review From the Data Pipeline Perspective

open access: yesAdvanced Intelligent Discovery, EarlyView.
The exponential growth of cancer multi‐omics data brings opportunities and challenges for precision oncology. This review systematically examines AI's role in addressing these challenges, covering generative models, integration architectures, Explainable AI for clinical trust, clinical applications, and key directions for clinical translation.
Shilong Liu, Shunxiang Li, Kun Qian
wiley   +1 more source

Spatially Informed Feature Selection and Machine Learning in Matrix‐Assisted Laser Desorption/Ionization Imaging for Cohort‐Scale Molecular Tissue Phenomics in Glioblastoma

open access: yesAdvanced Intelligent Discovery, EarlyView.
Matrix‐assisted laser desorption/ionization imaging‐based identification of reliable small molecule markers across heterogeneous glioblastoma cohorts is challenging with intensity‐only methods. We present spatially informed feature selection (SIFS), a spatially informed framework that prioritizes molecules consistently colocalizing with histopathology.
Shad A. Mohammed   +15 more
wiley   +1 more source

Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass-Spectrometry (MALDI-TOF MS) Based Microbial Identifications: Challenges and Scopes for Microbial Ecologists

open access: yesFrontiers in Microbiology, 2016
Matrix-assisted laser desorption/ionization time-of-flight mass-spectrometry (MALDI-TOF MS) based biotyping is an emerging technique for high-throughput and rapid microbial identification.
Parveen Rahi   +2 more
doaj   +1 more source

Examination of the Molecular Mass of Polyhydroxypolyamides [PDF]

open access: yes, 2010
The work described in this thesis investigated the use of size exclusion chromatography (SEC) to fractionate a variety of different polyhydroxypolyamide (PHPA) samples for analysis by matrix assisted laser desorption ionisation-time of flight ...
Faville, Martyn
core  

MALDI-TOF mass spectrometry on intact bacteria combined with a refined analysis framework allows accurate classification of MSSA and MRSA - Fig 1

open access: yes, 2019
MALDI-TOF positive ion mass spectra of MSSA (A) and MRSA (B) in the reflectron mode. Bacteria were grown on TSB medium, washed three times with double-distilled water and loaded into the MALDI target followed by the addition of the matrix directly on the
Nisha Ranganathan (6890060)   +3 more
core   +1 more source

The Role of MALDI-TOF Mass Spectrometry in Photodynamic Therapy: From Photosensitizer Design to Clinical Applications

open access: yesCurrent Issues in Molecular Biology
Photodynamic therapy (PDT) has evolved considerably over the past decades, progressing from first-generation porphyrins to second- and third-generation photosensitizers, including nanocarrier-based systems with improved selectivity and bioavailability ...
Dorota Bartusik-Aebisher   +2 more
doaj   +1 more source

Bayesian analysis of two methods MALDI-TOF-MS system and culture test in otomycosis infection

open access: yesWorld Journal of Otorhinolaryngology-Head and Neck Surgery, 2019
Objective: Identification of otomycotic fungi using matrix-assisted laser desorption ionization (MALDI) time of flight (TOF) mass spectroscopy (MS) and to quantify pervasive errors with Bayes rule; values of sensitivity and specificity of culture test ...
Sibanarayan Rath   +2 more
doaj   +1 more source

MALDI-TOF MS indicative peak masses of the different streptococcal species isolated from clinical specimens in pigs.

open access: yes, 2017
MALDI-TOF MS indicative peak masses of the different streptococcal species isolated from clinical specimens in pigs.
Sergio González (3500162)   +5 more
core   +1 more source

MALDI-ToF MS: a rapid methodology for identifying and subtyping Listeria monocytogenes

open access: yes, 2021
Listeria monocytogenes is a major food-borne pathogen and causative agent of a fatal disease, listeriosis. Stringent regulatory guidelines and zero tolerance policy toward this bacterium necessitate rapid, accurate, and reliable methods of identification
Snehal Jadhav (20010264)   +2 more
core  

Vergleich von Polyethylenglykol (PEG) und Poly(2‐ethyl‐2‐oxazolin) (PEtOx) für die lösungsmittelfreie Formulierung von Lipidnanopartikeln

open access: yesAngewandte Chemie, EarlyView.
Organische lösungsmittelfreie Lipidnanopartikel mit Stealth‐Lipiden auf PEtOx‐Basis ermöglichen einen effizienten Transport von mRNA und CRISPR‐Cas9 und weisen im Vergleich zu Analoga auf PEG‐Basis eine deutlich verbesserte Biokompatibilität auf.
Michael Streiber   +21 more
wiley   +1 more source

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