Results 121 to 130 of about 104,411 (250)

Real time in vivo efficacy monitoring of desialylation and perforation enhanced immunotherapy of cancer

BMEMat, EarlyView.
A multifunctional nanomedicine is designed to engineer NK cells for enhanced cancer immunotherapy through perforation and desialylation, enabling real‐time monitoring of ATP and GrB levels for precise efficacy assessment. Abstract Efficient enhanced NK cell therapy is of critical importance in the immune treatment of cancer.
Yuanjiao Yang, Yuru Wang, Xuemei Li, Chaoyi Yang, Yuhui Yang, Yanyun Fang, Lin Ding, Yunlong Chen, Huangxian Ju   +8 more
wiley   +1 more source

Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden

ChemFoodChem, EarlyView.
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley   +1 more source

Synthesis and Biological Evaluation of Well‐Defined M6P(n)‐Modified Glycopeptides for Targeted Protein Degradation

Chemistry – A European Journal, EarlyView.
A synthetic methodology has been developed to prepare multifunctional M6P and M6Pn ligands of different valency. The glycopeptides were conjugated to cetuximab and then examined to mediate cellular uptake of fluorescently labeled EGFRvIII. Only cetuximab modified by glycopeptides having 3 or 6 M6P or M6Pn residues demonstrated greater uptake.
Patrycja Lenartowicz, Jan‐Willem H. Langenbach, Nataliia Voloshyna, David Aidukas, Arwin J. Brouwer, John A. W. Kruijtzer, Geert‐Jan Boons   +6 more
wiley   +1 more source

Fusarium keratitis in an older adult without exogenous or traumatic risk factors: A case report on intrinsic ocular surface predisposition. [PDF]

IDCases
Huang T, Liang G, Jiang X, Gao Y, Wu H.
europepmc   +1 more source

Isodesmic Supramolecular Assembly of Phenylethynylene Bis‐Urea Macrocycles

Chemistry – A European Journal, EarlyView.
A soluble phenylethynylene bis‐urea macrocycle assembles in polar media via an isodesmic hydrogen bonded mechanism. Spectroscopic and morphological studies reveal nanoscale aggregates with short chain length, while guest additives modulate enthalpy and polymerization, demonstrating tunable supramolecular assembly.
Fahidat A. Gbadamosi, Kazi Md Zubaer, Vaibhavi A. Samant, Jillian Eubanks, Sophya Garashchuk, Linda S. Shimizu   +5 more
wiley   +1 more source

Integrated MALDI-TOF MS, Microbiological, Physicochemical and Sensory Assessment of Spoilage in Vacuum-Packaged Chicken Breast During Refrigerated Storage. [PDF]

Foods
Söylemez Milli N.
europepmc   +1 more source

Substituent‐Dependent Structural Trends in Thermal Condensation of Silanetriols and Disiloxanetetraols

Chemistry – A European Journal, EarlyView.
We report a catalyst‐ and solvent‐free thermal condensation route to oligosilsesquioxanes from arylsilanetriols and disiloxanetetraols. Phenyl and 1‐naphthyl systems form ladder‐like structures, while 2‐naphthyl systems yields layered architectures.
Jan‐Falk Kannengießer, Svenja Pohl, Bernd Morgenstern, Oliver Janka, Guido Kickelbick   +4 more
wiley   +1 more source

Negative-Ion Mode MALDI-TOF MS Combined with Machine Learning for the Rapid Identification of Colistin-Resistant <i>E. cloacae</i> Complex. [PDF]

ACS Omega
Shi Y, Gou X, Li Q, Wu J, Zhao Q, Chen Y, Luo W, Yang Y, Liang X, Long W, Wang J, Zhang J, Zhang X.   +12 more
europepmc   +1 more source

Synthesis and Structure of an S‐Shaped Double Expanded Helicene With Seven Fused Anthracene Units

Chemistry – A European Journal, EarlyView.
The anthracene‐fused aromatic compound was synthesized by four‐fold cycloisomerization of the corresponding alkyne precursor. X‐ray crystallographic analysis revealed that this compound had a double helical structure of Ci symmetry, in which the terminal and central anthracene units were triply stacked.
Shinji Toyota, Kaito Hohno, Takehiro Kihara, Yu Watanabe, Yuki Shigihara, Eiji Tsurumaki, Masahiro Yamashina   +6 more
wiley   +1 more source

eMALDI MS and oligonucleotide analysis. [PDF]

Chem Sci
Perera M, Yin Y, Arneson R, Razzaq F, Awasthy R, Wittstock W, Yuan Y, Fang S.   +7 more
europepmc   +1 more source