Results 121 to 130 of about 167,858 (299)

MALDI-TOF mass spectrometric analysis of the cellular MAs from M. bovis BCG Tokyo 172.

, 2019
MALDI-TOF mass spectrometric analysis of the cellular MAs from M. bovis BCG Tokyo 172.
Hiroyuki Nishiyama (105359), Takayuki Yoshino (616028), Takahiro Kojima (2327002), Hideyuki Akaza (6175745), Ikuya Yano (6175748), Masanobu Shiga (584068), Shuya Kandori (3387068), Miyuki Watanabe (6175742), Tomokazu Kimura (6175736), Hideyasu Kiyohara (6175739), Jun Miyazaki (1633828), Takashi Kawahara (294168), Takashi Naka (272391), Sho Yamasaki (522606)   +13 more
core   +1 more source

Die tRNA‐Modifikation Geranyl‐2‐thiouridin ermöglicht eine RNA‐Lipid Assoziation

Angewandte Chemie, EarlyView.
Wir berichten über die Herstellung mono‐ bis tri‐geranylierter RNA und über die Assoziation hydrophober RNA mit Membranen für einen künftigen effizienten Einbau von RNA in Liposomen. ZUSAMMENFASSUNG Die Verpackung von RNA in Lipid‐Nanopartikeln zum Schutz und Transport war für die Entwicklung von mRNA‐Impfstoffen und Medikamenten entscheidend.
Johannes Singer, Kathrin Halter, Chun‐Yin Chan, Thomas Carell   +3 more
wiley   +1 more source

Identification of ticks from North of Italy by MALDI-TOF MS

Ticks and Tick-Borne Diseases
Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) has recently emerged as a promising method for arthropods identification. A total of 125 ticks collected from 2013 until 2023 in Italy either stored frozen at –20
Maria Sampieri, Adama Zan Diarra, Lionel Almeras, Annalisa Grisendi, Mara Scremin, Giulia Maioli, Philippe Parola   +6 more
doaj   +1 more source

Swine Plasma peptides after PHx detected by magnetic bead-based LC-MALDI-TOF/TOF MS analyses.

, 2017
Swine Plasma peptides after PHx detected by magnetic bead-based LC-MALDI-TOF/TOF MS analyses.
Kohta Iguchi (3623009), Shinji Uemoto (95909), Nobuto Kakuda (3623024), Naohiko Nakamura (3623018), Yosuke Kasai (473540), Kei Tashiro (93122), Gen Yamamoto (3623012), Tomohito Sakai (3623021), Noriyuki Iwasaki (2001472), Motohiko Sato (219521), Hiroaki Fuji (3623003), Satoru Seo (3623015), Takashi Nirasawa (3623000), Kojiro Taura (3623006), Masaya Ikegawa (2270485), Tatsuya Okamoto (2070304), Kenya Yamanaka (731240), Etsuro Hatano (231684)   +17 more
core   +1 more source

MALDI glycotyping of O-antigens from a single colony of gram-negative bacteria

Scientific Reports
Polypeptide-targeted MALDI-TOF MS for microbial species identification has revolutionized microbiology. However, no practical MALDI-TOF MS identification method for O-antigen polysaccharides, a major indicator for epidemiological classification within a ...
Shogo Urakami, Hiroshi Hinou
doaj   +1 more source

Comparative Analysis of Poly(Ethylene Glycol) (PEG) and Poly(2‐Ethyl‐2‐Oxazoline) (PEtOx) for Organic Solvent‐Free Lipid Nanoparticle Formulations

Angewandte Chemie International Edition, EarlyView.
Organic solvent‐free lipid nanoparticles featuring PEtOx‐based stealth lipids enable efficient mRNA and CRISPR‐Cas9 delivery while exhibiting markedly improved biocompatibility compared with PEG‐based analogues. Their successful ex vivo and in vivo performance, combined with data‐driven formulation optimization, establishes a versatile platform that ...
Michael Streiber, Caroline T. Holick, Lucas Gath, Ekaterina Tsarenko, Vivien Bachmann, Stavroula Litsiou, Lukas Harder, Laura J. Rosenberger, Aleksandar Rusevski, Julian Kimmig, Stephan Culemann, Christian Franke, Claudia Waskow, Stephanie Hoeppener, Stephanie Schubert, Matthias Bros, Oliver Werz, Ivo Nischang, Michael Bauer, Adrian T. Press, Ulrich S. Schubert, Anja Traeger   +21 more
wiley   +1 more source

Optimization of MALDI Matrices and Their Preparation for the MALDI‐TOF MS Analysis of Oligonucleotides

Rapid Communications in Mass Spectrometry
ABSTRACT Rationale The reproducibility of the analysis of oligonucleotides using matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry (MALDI‐TOF MS) remains a significant challenge. This is mainly attributed to factors such as the choice and application of the matrix, as
Susanne Dietrich, Anja Dollinger, Andreas Wieser, Christoph Haisch   +3 more
openaire   +2 more sources

Imaging mass spectrometry approaches for the detection and localisation of drug compounds and small molecules in tissue [PDF]

A crucial and challenging aspect of the drug development process is the requirement to measure the distribution of a pharmaceutical compound and its metabolites in tissue.
Blatherwick, Eleanor Q.
core  

MALDI-MS spectra_external validation of the GA model

, 2019
MALDI mass spectra from hemolymph of individually challenged honey bees with either Micrococcus luteus or Pectobacterium carotovorum subsp. carotovorum strains and unchallenged control honey bees. These spectra were used to evaluate the capability of the
victor masson (7432746), Yves Le Conte (7432773), Karim ARAFAH (7431008), Cédric Alaux (7432756), Sébastien N. Voisin (7432749), michel bocquet (7432778), Philippe Bulet (7432783)   +6 more
core   +1 more source

The tRNA‐Modification Geranyl‐2‐Thiouridine Enables RNA‐Lipid Association

Angewandte Chemie International Edition, EarlyView.
We report the preparation of mono‐ to tri‐geranylated RNA and the association of the hydrophobic RNA with membranes for future efficient incorporation of RNA into liposomes. ABSTRACT The packaging of RNA in lipid nanoparticles for protection and delivery was key for the development of mRNA vaccines and therapeutics. Formulation requires the addition of
Johannes Singer, Kathrin Halter, Chun‐Yin Chan, Thomas Carell   +3 more
wiley   +1 more source