Results 11 to 20 of about 93,889 (197)
MALDI-MSI Towards Multimodal Imaging: Challenges and Perspectives [PDF]
Frontiers in Chemistry, 2022 Multimodal imaging is a powerful strategy for combining information from multiple images. It involves several fields in the acquisition, processing and interpretation of images.
Michael Tuck +3 more
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Research Progress on the Application of MALDI-MSI in Hair Analysis
Fayixue ZazhiMass spectrometry imaging （MSI） is an emerging high-tech “photography” method combining mass spectrometry and image visualization technologies, which can simultaneously monitor the spatial distribution of multiple molecules in biological samples.
JI Jiao-jiao +5 more
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Enhancing Metabolite Coverage in MALDI-MSI using Laser Post-Ionisation (MALDI-2). [PDF]
Analytical Methods, 2023 Matrix-assisted laser desorption/ionisation mass spectrometry imaging (MALDI-MSI) of metabolites can reveal how metabolism is altered throughout heterogeneous tissues. Here MALDI-MSI has been coupled with laser post-ionsiation (MALDI-2) and applied to the MSI of metabolites for the first time. Using mouse kidney and tumour-bearing liver tissue, MALDI-2
J. C. McKinnon +7 more
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A Matrix Sublimation Device with an Integrated Solvent Nebulizer for MALDI-MSI
Journal of the American Society for Mass Spectrometry, 2021 The current matrix deposition methods in MALDI-mass spectrometry imaging (MALDI-MSI) face technical problems related to the inhomogeneous distribution of crystals and the low analyte extraction and cocrystallization efficiency. In this work, an integrated matrix sublimation device with synchronous solvent nebulization was developed for MALDI-MSI ...
Huizhi Li +4 more
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Improved spectra for MALDI MSI of peptides using ammonium phosphate monobasic in MALDI matrix
Journal of Mass Spectrometry, 2018 AbstractMALDI mass spectrometry imaging (MSI) enables analysis of peptides along with histology. However, there are several critical steps in MALDI MSI of peptides, 1 of which is spectral quality. Suppression of MALDI matrix clusters by the aid of ammonium salts in MALDI experiments is well known.
Yasemin Ucal, Aysel Ozpinar
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MALDI MSI Protocol for Spatial Bottom-Up Proteomics at Single-Cell Resolution [PDF]
Journal of Proteome ResearchMatrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) started with spatial mapping of peptides and proteins. Since then, numerous bottom-up protocols have been developed.
Shane R. Ellis, Eva Cuypers, Ron Heeren
exaly +3 more sources
Statistical Modelling Investigation of MALDI-MSI-Based Approaches for Document Examination [PDF]
Molecules, 2023 Questioned document examination aims to assess if a document of interest has been forged. Spectroscopy-based methods are the gold standard for this type of evaluation.
Johan Kjeldbjerg Lassen +3 more
doaj +2 more sources
MALDI MSI of MeLiM melanoma: Searching for differences in protein profiles. [PDF]
PLoS ONE, 2017 Treatment of advanced cutaneous melanoma remains challenging, and new data on melanoma biology are required. The most widely accepted criteria for the prognostic evaluation of melanoma are histopathological and clinical parameters, and the identification
Roman Guran +7 more
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Advancing atherosclerosis research: The Power of lipid imaging with MALDI-MSI [PDF]
AtherosclerosisAtherosclerosis is a chronic inflammatory disease that is one of the leading causes of mortality globally. It is characterized by the formation of atheromatous plaques in the intima layer of larger arteries. The (fibro-)fatty plaques usually develop asymptomatically within the vessel until a serious event such as myocardial infarction or stroke occurs.
Christoph H.M. Bookmeyer +5 more
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P0659MULTIMODAL IMAGING OF MALDI MSI DATA [PDF]
Nephrology Dialysis Transplantation, 2020 Abstract Background and Aims MALDI mass spectrometric imaging (MALDI MSI) is a powerful histologic tool for the analysis of biomolecules in tissue samples. MALDI MSI measurements results in a high sensitivity and accuracy of spatial distribution of biomolecules in tissue samples The resolution ...
Joachim Jankowski +4 more
openaire +1 more source