Results 1 to 10 of about 3,961,195 (215)

Antioxidant Supplementation on Male Fertility—A Systematic Review

open access: yesAntioxidants, 2023
Our aim was to review the current literature regarding the effect of antioxidant supplementation (AS) on male fertility parameters, as AS is commonly used to treat male infertility due to the availability and affordability of antioxidants in many parts ...
Fotios Dimitriadis   +4 more
doaj   +2 more sources

Unraveling the harmful effect of oxidative stress on male fertility: A mechanistic insight

open access: yesFrontiers in Endocrinology, 2023
Male infertility is a widely debated issue that affects males globally. There are several mechanisms involved. Oxidative stress is accepted to be the main contributing factor, with sperm quality and quantity affected by the overproduction of free ...
Tarique Hussain   +10 more
semanticscholar   +1 more source

Mitochondria Quality Control and Male Fertility

open access: yesBiology, 2023
Simple Summary Mitochondria play a crucial role in numerous cellular processes, including energy production, apoptosis, and calcium homeostasis. In the male reproductive system, mitochondria are particularly important for the development and maintenance ...
José Costa   +4 more
semanticscholar   +1 more source

Identification of immune cell infiltration and effective biomarkers of polycystic ovary syndrome by bioinformatics analysis

open access: yesBMC Pregnancy and Childbirth, 2023
Background Patients with polycystic ovary syndrome (PCOS) exhibit a chronic inflammatory state, which is often accompanied by immune, endocrine, and metabolic disorders.
Mengge Gao   +5 more
doaj   +1 more source

Impact of environmental factors on human semen quality and male fertility: a narrative review

open access: yesEnvironmental Sciences Europe, 2022
Background Worldwide rising trend in infertility has been observed in the past few years with male infertility arising as a major problem. One main reason for the rise in male infertility cases is declining semen quality.
Naina Kumar, A. Singh
semanticscholar   +1 more source

Comprehensive Analysis of circRNAs, miRNAs, and mRNAs Expression Profiles and ceRNA Networks in Decidua of Unexplained Recurrent Spontaneous Abortion

open access: yesFrontiers in Genetics, 2022
The diagnosis and treatment of unexplained recurrent spontaneous abortion (URSA) are subject to debate, because the exact underlying mechanisms remain unclear. To address this issue, we elucidated the expression profiles of dysregulated circRNAs, miRNAs,
Xiaohua Liu   +13 more
doaj   +1 more source

Arachidonic Acid Pathways and Male Fertility: A Systematic Review

open access: yesInternational Journal of Molecular Sciences, 2023
Arachidonic acid (AA) is a polyunsaturated fatty acid that is involved in male fertility. Human seminal fluid contains different prostaglandins: PGE (PGE1 and PGE2), PGF2α, and their specific 19-hydroxy derivatives, 18,19-dehydro derivatives of PGE1 and ...
M. Hoxha, A. Barbonetti, B. Zappacosta
semanticscholar   +1 more source

A missense variant in NCF1 is associated with susceptibility to unexplained recurrent spontaneous abortion

open access: yesOpen Life Sciences, 2022
Unexplained recurrent spontaneous abortion (URSA) is a major concern in reproductive medicine. Neutrophil cytosolic factor 1 (NCF1) polymorphisms leading to low production of reactive oxygen species (ROS) are strongly associated with autoimmune diseases.
Du Mengxuan   +9 more
doaj   +1 more source

Testicular aging, male fertility and beyond

open access: yesFrontiers in Endocrinology, 2022
Normal spermatogenesis and sperm function are crucial for male fertility. The effects of healthy testicular aging and testicular premature aging on spermatogenesis, sperm function, and the spermatogenesis microenvironment cannot be ignored. Compared with
S. Dong   +5 more
semanticscholar   +1 more source

Prevalence of preconception TORCH infections and its influential factors: evidence from over 2 million women with fertility desire in southern China

open access: yesBMC Women's Health, 2023
Background TORCH (Toxoplasma gondii [TOX], Cytomegalovirus [CMV], Rubella virus [RV], and Herpes simplex virus [HSV]) represents pathogens known to traverse the maternal-fetal barrier and cause severe neonatal anomalies. We aimed to assess the prevalence
Lu Han   +9 more
doaj   +1 more source

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