Results 121 to 130 of about 181,476 (362)
Salt‐Compact Albumin as a New Pure Protein‐based Biomaterials: From Design to In Vivo Studies
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.A new class of materials built entirely of native albumin protein is designed using a simple protocol based on salt‐assisted compaction, breaking with current crosslinking strategies. This green process leads, surprisingly, to water‐insoluble handable materials with high preservation of their native protein structures and Young's modulus close to that ...
Eya Aloui +19 more
wiley +1 more source
Predicting DNA fragmentation: A non-destructive analogue to chemical assays using machine learning [PDF]
arXivGlobally, infertility rates are increasing, with 2.5\% of all births being assisted by in vitro fertilisation (IVF) in 2022. Male infertility is the cause for approximately half of these cases. The quality of sperm DNA has substantial impact on the success of IVF.
arxiv
Middle East Fertility Society Journal, 2018 Objective: The aim of this study was to compare intra-Cytoplasmic Sperm Injection (ICSI) outcomes (fertilization rate, embryo quality, pregnancy rate, and live birth rate) for couples with unexplained infertility and couples with male factor infertility,
Wardah Alasmari +6 more
doaj
A small population of hypothalamic neurons govern fertility: the critical role of VAX1 in GnRH neuron development and fertility maintenance. [PDF]
, 2016 Fertility depends on the correct maturation and function of approximately 800 gonadotropin-releasing hormone (GnRH) neurons in the brain. GnRH neurons are at the apex of the hypothalamic-pituitary-gonadal axis that regulates fertility. In adulthood, GnRH
Hoffmann, Hanne M, Mellon, Pamela L
core +1 more source
DNA fragmentation index (DFI) as a measure of sperm quality and fertility in mice. [PDF]
, 2020 Although thousands of genetically modified mouse strains have been cryopreserved by sperm freezing, the likelihood of cryorecovery success cannot be accurately predicted using conventional sperm parameters.
Li, Ming-Wen, Lloyd, KC Kent
core +1 more source
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.Glepaglutide (GL), a GLP‐2 analog with an extended half‐life (50 h), is currently undergoing clinical trials for patients with short bowel syndrome. GL requires subcutaneous injection, which poses challenges for potential patient compliance. To address this challenge, we loaded GL into a rectal foam formulation using CO2 as a permeation enhancer to ...
Wunan Zhang +9 more
wiley +1 more source
SHMC-Net: A Mask-guided Feature Fusion Network for Sperm Head Morphology Classification [PDF]
arXivMale infertility accounts for about one-third of global infertility cases. Manual assessment of sperm abnormalities through head morphology analysis encounters issues of observer variability and diagnostic discrepancies among experts. Its alternative, Computer-Assisted Semen Analysis (CASA), suffers from low-quality sperm images, small datasets, and ...
arxiv
Exact Reasoning Under Uncertainty [PDF]
arXiv, 2013 This paper focuses on designing expert systems to support decision making in complex, uncertain environments. In this context, our research indicates that strictly probabilistic representations, which enable the use of decision-theoretic reasoning, are highly preferable to recently proposed alternatives (e.g., fuzzy set theory and Dempster-Shafer ...
arxiv
UroInfertility is a significant global health issue, affecting 8–12% of couples of reproductive age, with male factor infertility contributing to 30–50% of cases.
Kristian Black +5 more
doaj +1 more source
Update on male reproductive endocrinology. [PDF]
, 2018 Practitioners of male reproductive and sexual medicine must have an intimate understanding of the physiology of male reproductive endocrinology, as such a knowledge is the cornerstone on which hormonal treatments are based.
Clavijo, Raul, Hsiao, Wayland
core +1 more source