Results 81 to 90 of about 177,590 (291)

Conditioned Media from Mechanically Stimulated Macrophages Upregulate Osteogenic Genes in Human Mesenchymal Stromal Cells

Advanced Healthcare Materials, EarlyView.
Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex, Ursula Menzel, Yann Ladner, Angela R. Armiento, Martin J. Stoddart   +4 more
wiley   +1 more source

Biologically Active Implants Prevent Mortality in a Mouse Sepsis Model

Advanced Healthcare Materials, EarlyView.
A modular, triple‐action titanium implant is developed to prevent implant‐associated infections by repelling bacteria, killing pathogens, and enhancing tissue integration. Coatings with phage cocktails targeting P. aeruginosa and S. aureus show significant bacterial reduction and improved survival in a mouse sepsis model.
Martin Stark, Fereshteh Bayat, Sara Rahmani, Mathura Thirugnanasampanthar, Taylor Kramer, Elise Schwarz, David Wilson, Jeffrey I. Weitz, Zeinab Hosseinidoust, Tohid F. Didar   +9 more
wiley   +1 more source

A Novel Brain Penetrable Nanocarrier Delivers Brain‐Derived Neurotrophic Factor to Treat Alzheimer's Disease

Advanced Healthcare Materials, EarlyView.
A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li, Elliya Park, Chunsheng He, Azhar Z. Abbasi, Pei Zhi, Paul E. Fraser, Andrew M. Rauth, Jeffery T. Henderson, Xiao Yu Wu   +8 more
wiley   +1 more source

Assessment of questionnaires measuring quality of life in infertile couples: A systematic review [PDF]

, 2013
Background: Infertility has potentially inappropriate effects on quality of life in infertile couples. Various general and specific questionnaires have been structured for assessing different aspects of quality of life in infertile men, women, or couples.
Keramat, A., Masoumi, S.Z., Mousavi, S.A., Pooralajal, J., Shobeiri, F.   +4 more
core   +1 more source

Genital manifestations of tropical diseases [PDF]

, 2004
Genital symptoms in tropical countries and among returned travellers can arise from a variety of bacterial, protozoal, and helminthic infections which are not usually sexually transmitted.
Richens, J
core   +2 more sources

Human Endometrial Extracellular Matrix Hydrogel Facilitated Endometrial Mesenchymal Stem Cells for Endometrial Regeneration

Advanced Healthcare Materials, EarlyView.
Adequate thickness of the uterine lining is crucial for women with thin or damaged endometrium to achieve pregnancies. Endometrial mesenchymal stem cells (eMSC) can facilitate the cyclical repair and regeneration of the human endometrium. In this study, the human endometrium derived extracellular matrix hydrogel supports the growth of eMSC promoting ...
Jingwen Xu, Philip C N Chiu, Ernest H Y Ng, Sentao Hu, Zi Ye, Liaobing Xin, Lie Ma, Songying Zhang, William S B Yeung, Rachel W S Chan   +9 more
wiley   +1 more source

ROS‐Scavenging Multifunctional Microneedle Patch Facilitating Wound Healing

Advanced Healthcare Materials, EarlyView.
A reactive oxygen species (ROS) scavenging and immunomodulatory microneedle patch based on hyaluronic acid methacrylate (HaMA) and Flightless I (Flii)‐siRNA‐laden arginine functionalized poly (β‐amino ester)/alginate particles is developed for chronic wound healing applications.
Mahshid Kharaziha, Sahar Salehi, Mahshid Shokri, Seyed Mohsen Ahmadi Tafti, Thomas Scheibel   +4 more
wiley   +1 more source

CHANGES IN IMMUNOGLOBULINS LEVEL (ANTISPERMAL ANTIBODIES OF A AND G CLASSES) IN PATIENTS WITH INFERTILITY ASSOCIATED WITH THE THERAPY BY PROSPERMATOGENIC BIOSTIMULATORS

Медицинский совет, 2017
Currently one of the problems presenting considerably clinical difficulties is the immune factor of the male infertility. In the structure of reasons of the male infertility, according to various literature sources, the immune factor is present in 5-15 ...
A. A. Kamalov, D. A. Okhobytov
doaj   +1 more source

Conceiving time?: women who do or do not conceive [PDF]

, 2007
This article explores the importance of time for an understanding of women's experiences of reproductive identity. In order to do this we draw on data from two separate qualitative research projects.
Acheson, Adam, Adam, Adam, Arber, Attar, Bamfield, Brown, Busfield, Cohen, Cotterill, Cotterill, Cussins, Darke, Davies, DiLapi, Douglas, Earle, Ehrenreich, Ettorre, Ettorre, Evans, Exley, Fox, Frankenberg, Franklin, Franklin, Franklin, Freund, Giddens, Glaser, Greil, Grosz, Grosz, Henrikson, Himmelweit, Hockey, Hull, Inhorn, Jacobus, Katz-Rothman, Kent, Kitzinger, Laslett, Laws, Letherby, Letherby, Lock, Martin, Menzies, Mills, Murphy, Oakley, Oakley, Oakley, Oechsle, Petchesky, Petchesky, Pfeffer, Pfeffer, Pfeffer, Pizzini, Posthill, Press, Press, Pritchard, Robertson, Roth, Shilling, Shorney, Simonds, Stanley, Stanley, Strauss, Taylor, Thomas, Turner, Turner, Woollett, Zola   +79 more
core   +1 more source

3D‐Printed Multidimensional Bionic Mg‐MC/PLGA Composite for Tailored Repair of Segmental Long Bone Defects

Advanced Healthcare Materials, EarlyView.
This study develops 3D‐printed Mg‐MC/PLGA scaffolds with varying Mg concentrations (0–20%). The 5% Mg scaffold shows optimal cytocompatibility, osteogenic activity in vitro, and significantly enhances bone regeneration in rabbits, improving bone volume and mechanical strength.
Shihang Liu, Shuai Zhou, Tingting Zou, Guangzhao Hou, Qian Xiao, Lin Li, Jianjun Yang, Wei Chen, Yingze Zhang, Hongzhi Lv   +9 more
wiley   +1 more source