Results 71 to 80 of about 1,973,836 (223)

Irr1/Scc3 Cohesin Interacts with Rec8 in Meiotic Prophase of Saccharomyces cerevisiae [PDF]

open access: yes, 2011
The meiotic cohesin complex of S. cerevisiae shares with the mitotic one the Irr1/Scc3, Smc1, and Smc3 subunits, while the meiosis-specific subunit Rec8 re-places mitotic subunit Scc1/Mcd1.
Cena, Agata   +7 more
core  

Bisphenol M Induces Dose‐Dependent Hepatic Injury and Fibrotic Remodeling in Female Mice

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT The safety of bisphenol analogs as alternatives to bisphenol A (BPA) is increasingly concerning. This study investigated the hepatotoxic effects of bisphenol M (BPM), a widely used BPA substitute, in 6‐week‐old female BALB/c mice exposed to 2.5, 5, and 10 mg/kg/day intraperitoneally for 14 days. Hepatic changes were assessed via histopathology,
Muhammed Canik   +3 more
wiley   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Unlocking the role of ClDYAD in initiating meiosis: A functional analysis in watermelon

open access: yesHorticultural Plant Journal
Watermelon (Citrullus lanatus), one of the top five fruit crops based on the gross tonnage and cultivated area globally, holds major economic importance in agriculture and contributes substantially to farmers’ incomes.
Xixi Wu   +8 more
doaj   +1 more source

ATR is required to complete meiotic recombination in mice

open access: yesNature Communications, 2018
ATR kinase is required for meiosis in non-mammalian model organisms. Here the authors demonstrate, using a hypomorphic Atr mutation and chemical inhibition, that ATR is also essential for male meiosis in mouse, regulating meiotic recombination and ...
Sarai Pacheco   +11 more
doaj   +1 more source

Effects of Obstructive Sleep Apnea on Personality and Temperament: A Cohort and Mendelian Randomization Study

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Obstructive sleep apnea (OSA) is associated with neurocognitive impairment, but its causal relationship with personality traits remains poorly understood. This study investigates the association and causality between OSA and personality using both cohort and genetic data.
Jian‐Hong Liao   +4 more
wiley   +1 more source

Reproductive Challenges of the Ageing Female: A Comprehensive Narrative Review

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Changes in societal norms over the last few decades have resulted in novel family planning trends, notably delayed childbearing and increased maternal age at the birth of the first child. Despite advances in reproductive medicine, ageing poses significant challenges.
Sofia Bitzika   +6 more
wiley   +1 more source

First report on a multiple sex chromosome system (X1X2X30) and population variations in the frequency of ring bivalents in Pyrrhocoridae (Hemiptera: Heteroptera)

open access: yesEuropean Journal of Entomology, 2015
The family Pyrrhocoridae (Hemiptera: Heteroptera) is characterized by a modal diploid chromosome number of 16 (♂) ranging from 12 to 33 and simple (X0), multiple (X1X20) and neo-sex chromosome systems (neoX-neoY).
Harbhajan KAUR, Kalchana GABA
doaj   +1 more source

Meiosis

open access: yes, 2011
Meiosis, the form of cell division unique to egg and sperm production, sets the stage for sex determination by creating sperm that carry either an X or a Y sex chromosome.Componente Curricular::Ensino Médio::BiologiaComponente Curricular::Educação ...
Howard Hughes Medical Institute (HHMI)
core  

Effect of Salinity Stress on Gut–Brain–Gonad Axis in the Red‐Eared Slider (Trachemys scripta elegans)

open access: yesIntegrative Zoology, EarlyView.
The increase in salinity leads to changes in the gut microbiota and metabolites of Trachemys scripta elegans, affecting the synthesis and secretion of neurotransmitters or precursors, which can inhibit the secretion of reproductive hormones and affect the self‐renewal and differentiation process of spermatogonial stem cells.
Qiongyu Zhang   +5 more
wiley   +1 more source

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