Results 111 to 120 of about 1,065,944 (354)

Association of CDKN2A/B Homozygous Deletion and Extent of Resection With Survival of Patients With WHO CNS5 Grade 4 Astrocytoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives WHO grade 4 astrocytomas are associated with poor prognosis, and their prognostic factors remain controversial. This study aimed to identify the prognostic factors and develop a management algorithm for these patients. Methods This study retrospectively included 151 CNS5 adult grade 4 astrocytomas from two medical centers.
Jiawei Cai   +13 more
wiley   +1 more source

Use of Nasonia vitripennis to Evaluate Genomic Imprinting and Haplodiploid Inheritance [PDF]

open access: yes, 2013
During fertilization, male and female gametes fuse and a diploid organism is generated. However, in some cases, not all of the genes from a parental genome are expressed.
Fisher, Carolyn
core   +1 more source

Environmental conditions during early life accelerate the rate of senescence in a short-lived passerine bird [PDF]

open access: yes, 2015
Environmental conditions experienced in early life may shape subsequent phenotypic traits including life history. We investigated how predation risk caused by domestic cats (Felis silvestris catus) and local breeding density affected patterns of ...
Balbontín Arenas, Javier   +1 more
core   +2 more sources

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

The epidemiology of cryptorchidism and potential risk factors, including endocrine disrupting chemicals

open access: yesFrontiers in Endocrinology
Congenital cryptorchidism, also known as undescended testis, is the condition where one or both testes are not in place in the scrotum at birth and is one of the most common birth defects in boys.
Stine A. Holmboe   +15 more
doaj   +1 more source

Love kills: Simulations in Penna Ageing Model

open access: yes, 2010
The standard Penna ageing model with sexual reproduction is enlarged by adding additional bit-strings for love: Marriage happens only if the male love strings are sufficiently different from the female ones.
A. O. SOUSA   +7 more
core   +1 more source

Feminist Reflections on the Scope of Labour Law: Domestic Work, Social Reproduction and Jurisdiction [PDF]

open access: yes, 2014
Drawing on feminist labour law and political economy literature, I argue that it is crucial to interrogate the personal and territorial scope of labour.
Andreas Wimmer   +74 more
core   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

The Emerging Roles of Protein Lipidation in Fertility and Reproductive Disorders: Mechanisms and Therapeutic Implications

open access: yesBiomolecules
Protein lipidation, a pivotal post-translational modification, dynamically regulates cellular signaling, membrane trafficking, and protein stability, with emerging roles in reproductive physiology.
Heran Cao   +6 more
doaj   +1 more source

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