Results 61 to 70 of about 39,927 (270)

Turning on the Heat by Cocrystal Engineering: The Rise of Organic Charge Transfer Photothermal Cocrystals as an Emerging Therapeutic Frontier in Biomedical Application

Aggregate, EarlyView.
This review summarizes recent developments in the design of photothermal charge transfer cocrystals for antibacterial therapy, cancer eradication, and bone regeneration, highlighting the design motivations and chemical principles of the strategies. It offers deep insights into the future development of advanced photothermal cocrystals for targeted ...
Arshad Khan, Rabia Usman, Shuo Xiang, Yasinalli Tamboli, Muhammad Umair, Awatef M. Alshehri, Ibraheem Bushnak, Yan Deng, Nongyue He   +8 more
wiley   +1 more source

Intraperitoneal chemotherapy for peritoneal metastases : an expert opinion

, 2020
Introduction: The rationale for intraperitoneal (IP) drug delivery for patients with peritoneal metastases (PM) is based on the pharmacokinetic advantage resulting from the peritoneal-plasma barrier, and on the potential to adequately treat small, poorly
Braet, Helena, Ceelen, Wim, Remaut, Katrien, Van Ramshorst, Gabrielle, Willaert, Wouter   +4 more
core   +1 more source

Using a Conformal Water Bolus to Adjust Heating Patterns of Microwave Waveguide Applicators [PDF]

, 2017
Background: Hyperthermia, i.e., raising tissue temperature to 40-45°C for 60 min, has been demonstrated to increase the effectiveness of radiation and chemotherapy for cancer.
Dewhirst, Drizdal, Drizdal, Hasgall, Neufield, Rodrigues, Stauffer, Stauffer, Trefna, van Rhoon   +9 more
core   +2 more sources

Memory and Learning Deficits Are Associated With Ca2+ Dyshomeostasis in Normal Aging

Frontiers in Aging Neuroscience, 2020
Neuronal intracellular Ca2+ homeostasis is critical to the normal physiological functions of neurons and neuronal Ca2+ dyshomeostasis has been associated with the age-related decline of cognitive functions.
Arkady Uryash, Valentina Flores, Jose A. Adams, Paul D. Allen, Jose R. Lopez   +4 more
doaj   +1 more source

Impact of different anesthetic protocols during anesthesia for the establishment of a porcine model of acute kidney injury

Animal Models and Experimental Medicine, EarlyView.
This study details the adaptations required to establish a long‐term anesthetic protocol in pigs. Three protocols were evaluated, with some causing malignant hyperthermia, hypoglycemia, or hemoynamic instability. The final protocol proved effective for developing a porcine AKI model requiring adequate arterial pressure maintenance.
Axel Guilpin, Mathieu Magnin, Axel Aigle, Timothée Schuhler, Jean‐Yves Ayoub, Romain Lac, Charlotte Slek, Thomas Brichart, Abdessalem Hammed, Vanessa Louzier   +9 more
wiley   +1 more source

Multifunctional Nanoparticles for Imaging Guided Interventions [PDF]

, 2008
We describe multifunctional magnetic nanoparticles (MNPs) encapsulated in thermosensitive, drug-bearing shells and delivered to the tumor site by genetically modified and non-pathogenic strains of bacteria with known affinity to tumors for an effective ...
Basel al-Ramadi, Bashar Issa, Hassan Hijaze, Saleh Hayek, Shahnaz Qadri, Yousef Haik   +5 more
core   +1 more source

Specific loss power of magnetic nanoparticles (fluid) hyperthermia in non-adiabatic conditions [PDF]

arXiv, 2021
We investigate the magnetic nanoparticles (fluid) hyperthermia in non-adiabatic conditions through the calorimetric method. Specifically, we propose a theoretical approach to magnetic hyperthermia from a thermodynamic point of view. To test the robustness of the approach, we perform hyperthermia experiments and analyze the thermal behavior of magnetite
arxiv  

Roadmap to Nanomedical Applications: Nanotoxicology and In Vitro Guidelines for Lanthanide‐Doped Luminescence Nanothermometers

Advanced NanoBiomed Research, EarlyView.
Lanthanide‐based luminescence nanothermometry holds multifaceted potential for nanomedical applications, yet despite significant research advances, clinical translation of the engineered nanomaterials is still controversial and widely disputed. This is related to crucial nanotoxicological aspects that must be addressed at the preclinical level ...
Simona Premcheska, Andre G. Skirtach, Anna M. Kaczmarek   +2 more
wiley   +1 more source

Molecular genetic analysis for malignant hyperthermia : a thesis presented to Massey University in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry [PDF]

, 2004
Malignant hyperthermia (MH) is a rare pharmacogenetic disorder in humans caused by inhalational general anaesthetics and depolarising muscle relaxants. An MH reaction shows abnormal calcium homeostasis in skeletal muscle leading to a hypermetabolic state
Sato, Keisaku
core  

Delayed-Onset Malignant Hyperthermia in Association with Rocuronium Use [PDF]

, 2012
Purpose Two cases of malignant hyperthermia suspected to be related to the use of a nondepolarizing neuromuscular blocker are reported. Summary A pharmacogenetic disorder that may occur in as many as 1 in 3000 anesthesia procedures, malignant ...
Beggs, Ashton E., McCann, Jennifer Quinn, Powers, Jan M.   +2 more
core   +2 more sources