Results 61 to 70 of about 38,467 (231)

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

BMEMat, EarlyView.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo, Nan Li, Daiwei Zhang, Jingya Gu, Zhihuan Liao, Zihao Teng, Xiangfu Du, Peter S. Timashev, Shipeng Chen, Shuaidong Huo   +9 more
wiley   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

Transforming Brain Health With Neurotechnology Convergence (Part II): Intelligent Neurointervention Systems for Neurological Disorders

Brain Health, EarlyView.
ABSTRACT Neurological disorders represent a critical domain within global health, necessitating advanced interventions to address complex pathologies such as tumors, functional disorders, and cerebrovascular diseases. Despite the proven benefits of early intervention, current treatment paradigms face significant challenges: (1) limited precision in ...
Qing Ye, Fei Peng, Chao Pan, Ping Zhang, Xuewei Xie, Zixiao Li, Yingxin Tang, Danyang Chen, Yuanwei Li, Jiawen Wu, Zao Han, Qing Dai, Quansheng Gu, Jizong Zhao, Zhouping Tang   +14 more
wiley   +1 more source

Management of malignant hyperthermia: diagnosis and treatment

Therapeutics and Clinical Risk Management, 2014
Daniel Schneiderbanger, Stephan Johannsen, Norbert Roewer, Frank SchusterDepartment of Anaesthesia and Critical Care, University of Wuerzburg, Wuerzburg, GermanyAbstract: Malignant hyperthermia is a potentially lethal inherited disorder characterized by ...
Schneiderbanger D, Johannsen S, Roewer N, Schuster F   +3 more
doaj  

MALIGNANT HYPERTHERMIA IN A CHILD AFTER MAGNETIC RESONANCE IMAGING: A CASE REPORT

Revista Paulista de Pediatria, 2020
Objective: To report on a case of malignant hyperthermia in a child after a magnetic resonance imaging of the skull was performed using sevoflurane anesthesia.
Carlos Gustavo de Almeida, José Colleti Junior   +1 more
doaj   +2 more sources

Nanoengineered neutrophils integrated with magnetic nanoparticles for T2‐weighted magnetic resonance imaging‐guided enhanced magnetic hyperthermia therapy of pancreatic tumor

Interdisciplinary Medicine, EarlyView.
An engineered neutrophil‐based targeted magnetic hyperthermia therapy was developed. Magnetic‐heat particles hitchhike on neutrophils that home to the tumor; under alternating magnetic fields the nano‐particles heat up to kill cancer cells and simultaneously trigger the cells to release reactive oxygen species for deeper clearance, doubling the punch ...
Muladili Mutailipu, Ran Cui, Tianxiao Mei, Zinan Zhao, Yongkun Wang, Chunxiu Dong, Bingdi Chen, Yihui Hu, Wenjun Le, Bo Chen   +9 more
wiley   +1 more source

Arsonic Acid Functional Polymers Enable Stabilization of Iron Oxide Nanoparticles in Aqueous Solution

Macromolecular Rapid Communications, EarlyView.
Arsonic acid containing diblock copolymers are developed to incorporate arsonic acid moieties for surface anchoring to IONPs, along with water soluble PEG blocks to impart colloidal stability in aqueous environments. The resulting polymer‐coated IONPs are evaluated for stability in physiological media and cytocompatibility.
Nhu Thao Huynh, Alexander Rajakanthan, Jurie Tashkandi, Rafia Rafique, Milad Ghorbani, Zihnil A. I. Mazrad, Nicole M. Warne, Kiyonori Suzuki, Karen Alt, Paul Wilson, Kristian Kempe   +10 more
wiley   +1 more source

Malignant hyperthermia

Southwest Respiratory and Critical Care Chronicles, 2016
Malignant hyperthermia is a rare metabolic crisis triggered by volatile anesthetics and/or succinylcholine. It is important to remember that hyperthermia is not always present and may even present late in the course.
Michael P Phy
doaj  

Synthesis and Application of Chitosan‐Salicylic Acid Magnetic Nanoparticles in Colon Cancer Cells

Nano Select, EarlyView.
This study reports the development of magnetic nanoparticles using chitosan as a stabilizer and conjugated with salicylic acid for colon cancer therapy. The biocompatible design enhances nanoparticle stability and enables selective toxicity against cancer cells while minimizing effects on normal cells.
Aida Ebadi, Mahla Mohammadi, Mohammad Mehdi Ebadi, Sarah Mousavi, Mohammad Mashreghi, Ali Es‐Haghi, Mohammad Ehsan Taghavizadeh Yazdi, Hossein Behmadi, Mohammad Qandalee, Carlos J. Durán‐Valle, Ignacio M. López‐Coca   +10 more
wiley   +1 more source

Disarming the Hsp70–Bim Alliance: Small‐Molecule and Peptidic Disruptors of a Chaperone‐Apoptotic Switch in Cancer

ChemistryOpen, EarlyView.
Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel, Mohammed Al‐zharani, Lina M. Alneghery, Noha A. Ahmed, Faris F. Aba Alkhayl, Al Mokhtar Lamsabhi   +5 more
wiley   +1 more source