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Dysembryoplastic neuroepithelial tumors (DNTs) are benign brain tumors classified as grade 1 in the 2021 World Health Organization (WHO) classification of central nervous system tumors.
Hirotaka Takita, MD +8 more
doaj +1 more source
Markers of Oral Lichen Planus Malignant Transformation [PDF]
Oral lichen planus (OLP) is a chronic inflammatory disease of unknown etiology with significant impact on patients’ quality of life. Malignant transformation into oral squamous cell carcinoma (OSCC) is considered as one of the most serious complications ...
Isabela Sarbu +9 more
core +1 more source
The Jamaica Education Transformation Commission, 2021: Summary of Recommendations
Jamaica’s education system boasts many successes: among these are relatively high enrolment rates at some levels, and world class universities that yield talented individuals of the highest calibre.
The Jamaica Education Transformation Commission
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Oral potentially malignant disorders: is malignant transformation predictable and preventable? [PDF]
Leukoplakia is the most common potentially malignant disorder of the oral mucosa. The prevalence is approxi - mately 1% while the annual malignant transformation ranges from 2% to 3%.
Van der Waal, Isaäc, van der Waal, I.
core +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Analysis of Epithelial Growth Factor-Receptor (EGFR) Phosphorylation in Uterine Smooth Muscle Tumors [PDF]
Uterine fibroids are the commonest uterine benign tumors. A potential mechanism of malignant transformation from leiomyomas to leiomyosarcomas has beendescribed.
Darius Dian +17 more
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Malignant Transformation of Oral Lichen Planus—An Umbrella Study of Systematic Reviews
Oral lichen planus (OLP) is classified as a potentially malignant disorder. Systematic reviews collating longitudinal observation studies provide evidence of the rate or proportion of malignant transformation.
Saman Warnakulasuriya +2 more
doaj +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Background To determine the prevalence of and risk factors for malignant transformation of ovarian endometrioma during dienogest therapy, which is very rare, we examined multiple cases of malignant transformation of ovarian endometrioma during dienogest ...
Michiko Honda +7 more
doaj +1 more source

