Results 41 to 50 of about 2,304,945 (294)
A case of neuroleptic malignant syndrome on withdrawal of benzhexol [PDF]
, 2010 The neuroleptic malignant syndrome is a rare and potentially lethal reaction which is usually associated with the use of medications with antidopaminergic properties.
Ferry, Peter +2 more
core
Malignant transformation arising in mature cystic teratoma [PDF]
, 2016 Background: The prognosis of patients with malignant transformation arising within mature cystic teratoma is poor. However, preoperative diagnosis is dif cult due to its rarity.
P Sherpa, TK Kansakar, R Baral
core +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Urothelial carcinoma arising from an ovarian mature cystic teratoma
Taiwanese Journal of Obstetrics & Gynecology, 2015 Objective: Ovarian mature cystic teratomas with malignant transformation are rare, and squamous cell carcinoma is the most common pathological entity. Among these malignant transformations, urothelial cell carcinoma is rare.
Hui-Yu Chuang +6 more
doaj +1 more source
Malignant Transformation of Hepatocellular Adenoma [PDF]
Hepatic Oncology, 2014 Hepatocellular adenomas carry a risk of malignant transformation. However, little is known about the rate of this risk, the predisposing factors, the histological and/or immunohistochemical markers and the precursor lesions. Even the pathogenesis of malignant transformation itself is poorly understood.
Christine, Sempoux +2 more
openaire +2 more sources
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Other title: Office of Children Services Transformation initial findings report
, 2020 "February 2020."; "Mike DeWine, Governor of Ohio; Jon Husted, Lt. Governor of Ohio."; "Ohio Governor's Children's Initiative, Children Services Transformation."; "Safe children. Stable homes.
Ohio. Children Services Transformation Advisory Council
core
Feasibility of recruitment to an oral dysplasia trial in the United Kingdom [PDF]
, 2012 Background: Oral epithelial dysplasia (OED) has a malignant potential. Therapeutic options for OED remain both limited and without good evidence. Despite surgery being the most common method of treating OED, recurrence and potentially significant ...
Nankivell, Paul +11 more
core +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Photodiagnosis and Photodynamic TherapyBackground: Photodynamic therapy (PDT) has shown good short-term efficacy in the treatment of oral leukoplakia (OLK). However, the malignant transformation of OLK was seldom evaluated in most PDT studies. Therefore, this study evaluated the effect of PDT
Yansong Song +10 more
doaj +1 more source