Results 11 to 20 of about 5,196,368 (357)

Protein tyrosine kinase inhibitor resistance in malignant tumors: molecular mechanisms and future perspective

Signal Transduction and Targeted Therapy, 2022
Protein tyrosine kinases (PTKs) are a class of proteins with tyrosine kinase activity that phosphorylate tyrosine residues of critical molecules in signaling pathways.
Yang Yang, Shuo Li, Yujiao Wang, Yi Zhao, Qiuhua Li   +4 more
semanticscholar   +1 more source

The regulatory and modulatory roles of TRP family channels in malignant tumors and relevant therapeutic strategies

Acta Pharmaceutica Sinica B, 2021
Transient receptor potential (TRP) channels are one primary type of calcium (Ca2+) permeable channels, and those relevant transmembrane and intracellular TRP channels were previously thought to be mainly associated with the regulation of cardiovascular ...
Tiecheng Zhong, Wenxin Zhang, Hongjie Guo, Xiaohui Pan, Xi Chen, Qiaojun He, Bo Yang, Ling Ding   +7 more
semanticscholar   +1 more source

Interactions between m6A modification and miRNAs in malignant tumors

Cell Death and Disease, 2021
Recently, the regulatory role of epigenetic modifications in the occurrence and development of malignant tumors has attracted extensive attention.
Xiao Han, Jing Guo, Z. Fan
semanticscholar   +1 more source

Benign vs Malignant Tumors.

JAMA Oncology, 2020
Benign Tumors Benign tumors are those that stay in their primary location without invading other sites of the body. They do not spread to local structures or to distant parts of the body.
Aisha Patel
semanticscholar   +1 more source

Heating technology for malignant tumors: a review

International Journal of Hyperthermia, 2020
The therapeutic application of heat is very effective in cancer treatment. Both hyperthermia, i.e., heating to 39–45 °C to induce sensitization to radiotherapy and chemotherapy, and thermal ablation, where temperatures beyond 50 °C destroy tumor cells ...
H. Kok, E. N. Cressman, W. Ceelen, C. Brace, R. Ivkov, H. Grüll, G. ter Haar, P. Wust, J. Crezee   +8 more
semanticscholar   +1 more source

CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2015-2019.

Neuro-Oncology, 2022
The Central Brain Tumor Registry of the United States (CBTRUS), in collaboration with the Centers for Disease Control and Prevention and the National Cancer Institute, is the largest population-based registry focused exclusively on primary brain and ...
Q. Ostrom, M. Price, C. Neff, G. Cioffi, K. Waite, C. Kruchko, J. Barnholtz-Sloan   +6 more
semanticscholar   +1 more source

Integrating scRNA and bulk-RNA sequencing develops a cell senescence signature for analyzing tumor heterogeneity in clear cell renal cell carcinoma

Frontiers in Immunology, 2023
IntroductionCellular senescence (CS) plays a critical role in cancer development, including clear cell renal cell carcinoma (ccRCC). Traditional RNA sequencing cannot detect precise molecular composition changes within tumors. This study aimed to analyze
Qiming Gong, Qiming Gong, Yan Jiang, Junfeng Xiong, Fahui Liu, Jikui Guan   +5 more
doaj   +1 more source

CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2016-2020.

Neuro-Oncology, 2023
The Central Brain Tumor Registry of the United States (CBTRUS), in collaboration with the Centers for Disease Control and Prevention and the National Cancer Institute, is the largest population-based registry focused exclusively on primary brain and ...
Q. Ostrom, M. Price, C. Neff, G. Cioffi, K. Waite, C. Kruchko, J. Barnholtz-Sloan   +6 more
semanticscholar   +1 more source

Prognostic Value of Choline and Other Metabolites Measured Using ¹H-Magnetic Resonance Spectroscopy in Gliomas: A Meta-Analysis and Systemic Review

Metabolites, 2022
Glioma is the most prevalent primary central nervous system malignant tumor, with high heterogeneity observed among different grades; therefore, non-invasive prediction of prognosis could improve the clinical management of patients with glioma.
Yixin Shi, Delin Liu, Ziren Kong, Qianshu Liu, Hao Xing, Yuekun Wang, Yu Wang, Wenbin Ma   +7 more
doaj   +1 more source

Accuracy of computerized tomography in determining hepatic tumor size in patients receiving liver transplantation or resection [PDF]

, 1984
Computerized tomography (CT) of liver is used in oncologic practice for staging tumors, evaluating response to treatment, and screening patients for hepatic resection.
Bron, K, Dekker, A, Iwatsuki, S, Kowal, C, Mittal, R, Schade, R, Starzl, T, Straub, W, Van Thiel, D   +8 more
core   +1 more source