Results 1 to 10 of about 43,936 (351)

Anticancer Potency of Dimethyl 2-(2-Hydroxy-2-Methoxypropilidine) Malonate in Kombucha [PDF]

open access: yesJurnal Biodjati, 2022
Kombucha has an anticancer potency because it has dimethyl 2-(2-hydroxy-2-methoxypropilidine) malonate compound. The research aimed to verify the compound dimethyl 2-(2-hydroxy-2-methoxypropilidine) malonate as an anticancer with the in-silico method ...
Opik Taupiqurrohman   +3 more
doaj   +4 more sources

Malonate inhibits virulence gene expression in Vibrio cholerae. [PDF]

open access: yesPLoS ONE, 2013
We previously found that inhibition of the TCA cycle, either through mutations or chemical inhibition, increased toxT transcription in Vibrio cholerae.
Yusuke Minato   +2 more
doaj   +2 more sources

Melaminium hydrogen malonate [PDF]

open access: yesActa Crystallographica Section E, 2012
The melaminium (2,4,6-triamino-1,3,5-triazin-1-ium) cation in the title compound, C3H7N6+·C3H3O4−, is essentially planar, with a r.m.s. deviation of the non-H atoms of 0.0085 Å.
Barbara Froschauer, Matthias Weil
doaj   +4 more sources

Genomic characterization of malonate positive Cronobacter sakazakii serotype O:2, sequence type 64 strains, isolated from clinical, food, and environment samples

open access: yesGut Pathogens, 2018
Background Malonate utilization, an important differential trait, well recognized as being possessed by six of the seven Cronobacter species is thought to be largely absent in Cronobacter sakazakii (Csak). The current study provides experimental evidence
Gopal R. Gopinath   +26 more
doaj   +2 more sources

Crystal structure of a Pseudomonas malonate decarboxylase holoenzyme hetero-tetramer

open access: yesNature Communications, 2017
Some aerobic bacteria contain a biotin-independent malonate decarboxylase (MDC), which allows them to use malonate as the sole carbon source. Here, the authors present the crystal structure of a Pseudomonas MDC and give insights into its catalytic ...
Riyaz Maderbocus   +6 more
doaj   +2 more sources

Succinate dehydrogenase inhibitor dimethyl malonate alleviates LPS/-galactosamine-induced acute hepatic damage in mice

open access: yesInnate Immunity, 2019
In addition to its energy-supplying function, increasing evidence suggests that mitochondria also play crucial roles in the regulation of inflammation.
Yongqiang Yang   +7 more
doaj   +2 more sources

Crystal structure and identification of resonance forms of diethyl 2-(3-oxoiso-1,3-dihydrobenzofuran-1-ylidene)malonate [PDF]

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2017
The reaction of diethyl malonate with phthaloyl chloride in acetonitrile in the presence of triethylamine and magnesium chloride results in the formation of the title compound, diethyl 2-(3-oxo-1,3-dihydro-2-benzofuran-1-ylidene)propanedioate, C15H14O6 ...
Mikhail S. Tyumentsev   +3 more
doaj   +4 more sources

Ischemia-Selective Cardioprotection by Malonate for Ischemia/Reperfusion Injury

open access: yesCirculation Research, 2022
Background: Inhibiting SDH (succinate dehydrogenase), with the competitive inhibitor malonate, has shown promise in ameliorating ischemia/reperfusion injury. However, key for translation to the clinic is understanding the mechanism of malonate entry into
H. Prag   +14 more
semanticscholar   +1 more source

Malonate Promotes Adult Cardiomyocyte Proliferation and Heart Regeneration

open access: yesCirculation, 2021
Supplemental Digital Content is available in the text. Background: Neonatal mouse cardiomyocytes undergo a metabolic switch from glycolysis to oxidative phosphorylation, which results in a significant increase in reactive oxygen species production that ...
Jiyoung Bae   +8 more
semanticscholar   +1 more source

Asymmetric Hydrogenation of β-Aryl Alkylidene Malonate Esters: Installing an Ester Group Significantly Increases the Efficiency.

open access: yesOrganic Letters, 2021
Herein, we report a practical method for efficient asymmetric hydrogenation of β-aryl alkylidene malonates. With a site-specifically tailored chiral spiro iridium catalyst, a series of β-aryl alkylidene malonate esters were hydrogenated to afford chiral ...
Qiankun Zhao   +5 more
semanticscholar   +1 more source

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