Results 1 to 10 of about 48,393 (330)

Anticancer Potency of Dimethyl 2-(2-Hydroxy-2-Methoxypropilidine) Malonate in Kombucha

open access: goldJurnal Biodjati, 2022
Kombucha has an anticancer potency because it has dimethyl 2-(2-hydroxy-2-methoxypropilidine) malonate compound. The research aimed to verify the compound dimethyl 2-(2-hydroxy-2-methoxypropilidine) malonate as an anticancer with the in-silico method ...
Opik Taupiqurrohman   +3 more
doaj   +4 more sources

Crystal structure of diethyl 2-[(2-sulfanylquinolin-3-yl)methylidene]malonate [PDF]

open access: goldActa Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C17H17N O4S, the quinoline ring system is nearly planar, with a maximum deviation of 0.0496 (16) Å. A weak intramolecular C—H...O interaction is observed.
Rihanabanu   +4 more
doaj   +2 more sources

Focal Malonate Injection Into the Internal Capsule of Rats as a Model of Lacunar Stroke

open access: yesFrontiers in Neurology, 2018
Background: Stroke is the first cause of disability in adults in western countries. Infarct of the internal capsule (IC) may be related to motor impairment and poor prognosis in stroke patients.
Carla Cirillo   +6 more
doaj   +2 more sources

Melaminium hydrogen malonate [PDF]

open access: yesActa Crystallographica Section E, 2012
The melaminium (2,4,6-triamino-1,3,5-triazin-1-ium) cation in the title compound, C3H7N6+·C3H3O4−, is essentially planar, with a r.m.s. deviation of the non-H atoms of 0.0085 Å.
Barbara Froschauer, Matthias Weil
doaj   +3 more sources

Targeting succinate dehydrogenase with malonate ester prodrugs decreases renal ischemia reperfusion injury

open access: yesRedox Biology, 2020
Renal ischemia reperfusion (IR) injury leads to significant patient morbidity and mortality, and its amelioration is an urgent unmet clinical need.
Hiran A Prag, Laura Pala, Angela Logan
exaly   +3 more sources

Malonate inhibits virulence gene expression in Vibrio cholerae. [PDF]

open access: yesPLoS ONE, 2013
We previously found that inhibition of the TCA cycle, either through mutations or chemical inhibition, increased toxT transcription in Vibrio cholerae.
Yusuke Minato   +2 more
doaj   +2 more sources

Crystal structure of bis(4-methoxyphenyl) malonate [PDF]

open access: goldActa Crystallographica Section E: Crystallographic Communications, 2015
The complete molecule of the title compound, C17H16O6, is generated by crystallographic twofold symmetry, with the central methylene C atom lying on the rotation axis.
H. C. Devarajegowda   +4 more
doaj   +2 more sources

Genomic characterization of malonate positive Cronobacter sakazakii serotype O:2, sequence type 64 strains, isolated from clinical, food, and environment samples

open access: yesGut Pathogens, 2018
Background Malonate utilization, an important differential trait, well recognized as being possessed by six of the seven Cronobacter species is thought to be largely absent in Cronobacter sakazakii (Csak). The current study provides experimental evidence
Gopal R. Gopinath   +26 more
doaj   +2 more sources

Selective Inhibition of Succinate Dehydrogenase in Reperfused Myocardium with Intracoronary Malonate Reduces Infarct Size

open access: yesScientific Reports, 2018
Inhibition of succinate dehydrogenase (SDH) with malonate during reperfusion reduces infarct size in isolated mice hearts submitted to global ischemia. However, malonate has toxic effects that preclude its systemic administration in animals.
Ignasi Barba   +2 more
exaly   +2 more sources

Succinate dehydrogenase inhibitor dimethyl malonate alleviates LPS/-galactosamine-induced acute hepatic damage in mice

open access: yesInnate Immunity, 2019
In addition to its energy-supplying function, increasing evidence suggests that mitochondria also play crucial roles in the regulation of inflammation.
Yongqiang Yang   +7 more
doaj   +2 more sources

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