Results 1 to 10 of about 22,523 (167)
Anticancer Potency of Dimethyl 2-(2-Hydroxy-2-Methoxypropilidine) Malonate in Kombucha
Kombucha has an anticancer potency because it has dimethyl 2-(2-hydroxy-2-methoxypropilidine) malonate compound. The research aimed to verify the compound dimethyl 2-(2-hydroxy-2-methoxypropilidine) malonate as an anticancer with the in-silico method ...
Opik Taupiqurrohman+3 more
doaj +2 more sources
Malonate inhibits virulence gene expression in Vibrio cholerae. [PDF]
We previously found that inhibition of the TCA cycle, either through mutations or chemical inhibition, increased toxT transcription in Vibrio cholerae.
Yusuke Minato+2 more
doaj +2 more sources
Preparation of mono-substituted malonic acid half oxyesters (SMAHOs)
The use of mono-substituted malonic acid half oxyesters (SMAHOs) has been hampered by the sporadic references describing their preparation. An evaluation of different approaches has been achieved, allowing to define the best strategies to introduce ...
Tania Xavier+4 more
doaj +1 more source
Probing the Binding Requirements of Modified Nucleosides with the DNA Nuclease SNM1A
SNM1A is a nuclease that is implicated in DNA interstrand crosslink repair and, as such, its inhibition is of interest for overcoming resistance to chemotherapeutic crosslinking agents.
Eva-Maria Dürr, Joanna F. McGouran
doaj +1 more source
Uncoupling Protein 3 Catalyzes the Exchange of C4 Metabolites Similar to UCP2
Uncoupling protein 3 (UCP3) belongs to the mitochondrial carrier protein superfamily SLC25 and is abundant in brown adipose tissue (BAT), the heart, and muscles.
Jürgen Kreiter+2 more
doaj +1 more source
There is an urgent need to find novel treatments for combating multidrug-resistant bacteria. Multidrug efflux pumps that expel antibiotics out of cells are major contributors to this problem.
Allea Cauilan, Cristian Ruiz
doaj +1 more source
The title compound, C18H23FO5, was synthesized by reacting diethyl malonate with 1-(4-fluorophenyl)-3-methylbut-2-en-1-one. The molecule adopts a loose conformation stabilized by weak C—H...O and C—H...π interactions.
Sandeep Chandrashekharappa+4 more
doaj +1 more source
Crystal structure of diethyl 2-[(2-sulfanylquinolin-3-yl)methylidene]malonate
In the title compound, C17H17N O4S, the quinoline ring system is nearly planar, with a maximum deviation of 0.0496 (16) Å. A weak intramolecular C—H...O interaction is observed.
Rihanabanu+4 more
doaj +1 more source
Theoretical Evaluation of Refractive Index in Binary Liquid Mixtures
The density and refractive index (RI) for four binary liquid mixtures: diethyl malonate + dimethylformamide (DEM+DMF), diethyl malonate + Hexane (DEM+HEX), diethyl malonate + tetrahydrofuran (DEM+THF), diethyl malonate + 1,4-dioxane (DEM+DO) have been ...
Shipra Baluja+3 more
doaj +1 more source
Disodium malonate impairs human sperm motility by inhibiting succinate dehydrogenase activity [PDF]
Objective To investigate the impact of succinate dehydrogenase (SDH) on the modulation of human sperm functions. Methods The isolated human sperm were co-incubated with different concentrations (10, 20, 40 mmol/L) of SDH inhibitor
PENG Zhen, WEN Qin, LU Jing, TU Zeliang, CHENG Yimin
doaj +1 more source