Results 11 to 20 of about 48,393 (330)

Crystal structure of a Pseudomonas malonate decarboxylase holoenzyme hetero-tetramer

Nature Communications, 2017
Some aerobic bacteria contain a biotin-independent malonate decarboxylase (MDC), which allows them to use malonate as the sole carbon source. Here, the authors present the crystal structure of a Pseudomonas MDC and give insights into its catalytic ...
Riyaz Maderbocus, Blanche L. Fields, Keith Hamilton, Shukun Luo, Timothy H. Tran, Lars E. P. Dietrich, Liang Tong   +6 more
doaj   +2 more sources

2,3-Diaminopyridinium hydrogen malonate [PDF]

Acta Crystallographica Section E, 2013
In the title molecular salt, C5H8N3+·C3H3O4−, the cation is essentially planar, with a maximum deviation of 0.005 (1) Å for all non-H atoms.
Ibrahim Abdul Razak, Suhana Arshad, Nuridayanti Che Khalib, Kaliyaperumal Thanigaimani   +3 more
doaj   +3 more sources

Dimethyl 2-(2,4,6-trimethoxybenzyl)malonate

Acta Crystallographica Section E, 2010
In the title compound, C15H20O7, the benzene ring makes dihedral angles of 69.17 (5) and 80.81 (4)° with the two side chains of malonate.
Shou-Xin Liu, Xin Lu, Shi-Rui Gao, Jian-Rong Han, Xiao-Li Zhen   +4 more
doaj   +2 more sources

The inhibition of 2-arachidonoyl-glycerol (2-AG) biosynthesis, rather than enhancing striatal damage, protects striatal neurons from malonate-induced death: a potential role of cyclooxygenase-2-dependent metabolism of 2-AG

Cell Death and Disease, 2013
The cannabinoid CB2 receptor, which is activated by the endocannabinoid 2-arachidonoyl-glycerol (2-AG), protects striatal neurons from apoptotic death caused by the local administration of malonate, a rat model of Huntington’s disease (HD).
Fabiana Piscitelli, Fabio Arturo Iannotti, Vincenzo Di Marzo   +2 more
exaly   +2 more sources

Malonate induces the assembly of cytoplasmic stress granules [PDF]

FEBS Letters, 2015
Xue Fu, Xingjie Gao, Lin Ge, Xiaoteng Cui, Chao Su, Wendong Yang, Xiaoming Sun, Wei Zhang, Zhi Yao, Xi Yang, Jie Yang   +10 more
openalex   +2 more sources

Succinate dehydrogenase inhibition with malonate during reperfusion reduces infarct size by preventing mitochondrial permeability transition

Cardiovascular Research, 2016
Ignasi Barba, Marisol Ruiz-Meana
exaly   +2 more sources

Ischemia-Selective Cardioprotection by Malonate for Ischemia/Reperfusion Injury

Circulation Research, 2022
Background: Inhibiting SDH (succinate dehydrogenase), with the competitive inhibitor malonate, has shown promise in ameliorating ischemia/reperfusion injury. However, key for translation to the clinic is understanding the mechanism of malonate entry into
H. Prag, D. Aksentijević, Andreas Dannhorn, Abigail V Giles, J. Mulvey, Olga Sauchanka, Luping Du, Georgina R Bates, J. Reinhold, Duvaraka Kula-Alwar, Zhelong Xu, L. Pellerin, R. Goodwin, M. Murphy, T. Krieg   +14 more
semanticscholar   +1 more source

Malonate Promotes Adult Cardiomyocyte Proliferation and Heart Regeneration

Circulation, 2021
Supplemental Digital Content is available in the text. Background: Neonatal mouse cardiomyocytes undergo a metabolic switch from glycolysis to oxidative phosphorylation, which results in a significant increase in reactive oxygen species production that ...
Jiyoung Bae, Rebecca J Salamon, Emma B. Brandt, Wyatt G. Paltzer, Ziheng Zhang, Emily C. Britt, T. Hacker, Jing Fan, A. Mahmoud   +8 more
semanticscholar   +1 more source

Asymmetric Hydrogenation of β-Aryl Alkylidene Malonate Esters: Installing an Ester Group Significantly Increases the Efficiency.

Organic Letters, 2021
Herein, we report a practical method for efficient asymmetric hydrogenation of β-aryl alkylidene malonates. With a site-specifically tailored chiral spiro iridium catalyst, a series of β-aryl alkylidene malonate esters were hydrogenated to afford chiral ...
Qiankun Zhao, Xiong Wu, Lin-Ping Li, Fan Yang, Jian-Hua Xie, Qi‐Lin Zhou   +5 more
semanticscholar   +1 more source

Malonate utilization by Pseudomonas aeruginosa affects quorum‐sensing and virulence and leads to formation of mineralized biofilm‐like structures

Molecular Microbiology, 2021
Pseudomonas aeruginosa is an opportunistic pathogen that uses malonate among its many carbon sources. We recently reported that, when grown in blood from trauma patients, P. aeruginosa expression of malonate utilization genes was upregulated.
Moamen M. Elmassry, Karishma Bisht, J. Colmer-Hamood, Catherine A. Wakeman, M. S. San Francisco, A. Hamood   +5 more
semanticscholar   +1 more source