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Lipofuscin-like fluorophores originated from malondialdehyde

Free Radical Research, 2006
The accumulation of fluorescent age pigment or lipofuscin is a frequently observed age-associated cellular alteration in a variety of post-mitotic cells of many species. These pigments are observed within granules composed, in part, of damaged protein and lipid.
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Lipid peroxidation—DNA damage by malondialdehyde

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 1999
Malondialdehyde is a naturally occurring product of lipid peroxidation and prostaglandin biosynthesis that is mutagenic and carcinogenic. It reacts with DNA to form adducts to deoxyguanosine and deoxyadenosine. The major adduct to DNA is a pyrimidopurinone called M1G.
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Malondialdehyde

2008
Vasu Nair   +2 more
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Some Derivatives of Malondialdehyde

The Journal of Organic Chemistry, 1957
T. L. V. ULBRICHT, CHARLES C. PRICE
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Malonaldehyde (malondialdehyde).

IARC monographs on the evaluation of carcinogenic risks to humans, 1999
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Über Malondialdehyd, I. Mitteilung

Berichte der deutschen chemischen Gesellschaft (A and B Series), 1941
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