Results 51 to 60 of about 36,656 (302)

Acute median arcuate ligament syndrome after pancreaticoduodenectomy

open access: yesSurgical Case Reports, 2018
Background Median arcuate ligament syndrome (MALS) can cause severe complications after pancreaticoduodenectomy (PD). Most of the reported cases of MALS have been diagnosed perioperatively and can be treated efficiently by interventional radiology or ...
Daisuke Imai   +10 more
doaj   +1 more source

Coupling Multi Angle Light Scattering to Ion Exchange chromatography (IEX-MALS) for protein characterization

open access: yes, 2018
Multi-angle light scattering coupled with size exclusion chromatography (SEC-MALS) is a standard and common approach for characterizing protein mass, overall shape, aggregation, oligomerization, interactions and purity.
Assaf Friedler   +4 more
core   +1 more source

Doubling time (hours) and yield of all the MALs across multiple time points during mutation accumulation.

open access: yes, 2023
Doubling time (hours) and yield of all the MALs across multiple time points during mutation accumulation.
Jia-Xing Yue (3405950)   +6 more
core   +1 more source

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

open access: yesAdvanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu   +12 more
wiley   +1 more source

Detection of Protein–Protein Interactions in Escherichia coli With Single Molecule Sensitivity

open access: yesAdvanced Science, EarlyView.
This article describes a regulatory circuit in Escherichia coli able to detect protein–protein interactions with exquisite sensitivity. The interaction between two hybrid proteins fused to Bordetella pertussis adenylate cyclase and its activator calmodulin triggers a potent cyclic AMP signaling cascade.
Marilyne Davi, Daniel Ladant
wiley   +1 more source

Laparoscopic treatment for median arcuate ligament syndrome in children: A case report

open access: yesRadiology Case Reports
In median arcuate ligament syndrome (MALS), the median arcuate ligament compresses the celiac trunk and surrounding nerves leading to chronic functional abdominal pain and vague gastrointestinal symptoms.
Trinh-Nguyen Ha Vi, MD   +6 more
doaj   +1 more source

A Radioresistant‐Tumor‐Targeted Nanoparticle for X‐Ray‐Controlled Nitric Oxide Release to Potentiate Radiotherapy

open access: yesAdvanced Science, EarlyView.
The PBTN targets GRP78 and, upon X‐ray irradiation, generates ONOO− to induce immunogenic cell death, thereby activating CD8+ T cells and establishing a systemic antitumor immune response. ABSTRACT Nitric oxide (NO) treated radioresistant tumors by relieving hypoxia and blocking DNA repair, but its nonselective toxicity has precluded therapeutic use ...
Wanze Zhang   +10 more
wiley   +1 more source

Usefulness of Size-Exclusion Chromatography–Multi-Angle Light Scattering to Assess Particle Composition and Protein Impurities for Quality Control of Therapeutic Exosome Preparations

open access: yesPharmaceutics
Background: Extracellular vesicles (EVs), including exosomes, are promising pharmaceutical modalities. They are purified from cell culture supernatant; however, the preparation may contain EVs with the desired therapeutic effects and different types of ...
Hirotaka Nishimura   +6 more
doaj   +1 more source

Median Arcuate Ligament Syndrome (MALS) Explained

open access: yes, 2020
Median Arcuate Ligament Syndrome (MALS) is a rare condition caused by the median arcuate ligament compressing the celiac plexus. Families are challenged to find reliable information about MALS, its treatment, and what to expect after medical intervention.
Meyer, Katherine
core  

MALS and AUC based analysis of solution oligomeric state.

open access: yes, 2013
a) MALS data for GACwt displaying mass fractions of oligomeric species in the protein solution in the protein concentration range 1.4 µM to 9.7 µM as detected on MALS with estimated Rz values (RMS radius) given on the x-axis. Elution concentration of the
Bente Vestergaard (73256)   +9 more
core   +1 more source

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