Results 71 to 80 of about 36,656 (302)

Mal absoluto, mal radical, banalidad del mal. La comprensión del mal en Hannah Arendt

open access: yesBajo Palabra, 2019
The aim of this article is to provide a panoramic exposition of Hannah Arendt’s thought about the issue of evil. In order to achieve this task, I will pose briefly Kant’s approach of ‘radical evil’, which had an enormous relevance for Arendt. Then, I will point out the stance held by her in The Origins of Totalitarianism and later to explain the way ...
openaire   +3 more sources

SpaMode: A Broadly Applicable Framework for Deciphering Spatial Multi‐Omics Using Multimodal Mixture of Disentangled Experts

open access: yesAdvanced Science, EarlyView.
SpaMode introduces a versatile framework for spatial multi‐omics integration across vertical, horizontal, and mosaic scenarios. By disentangling modality‐invariant and variant features through a mixture‐of‐experts mechanism, it adaptively reconfigures spatially heterogeneous signals.
Xubin Zheng   +6 more
wiley   +1 more source

Oligomerization state of DUSP26-N (C152S) in solution as determined by SEC-MALS.

open access: yes, 2016
The molecular mass of DUSP26-N (C152S) was calculated from the elution profile examined by analytical SEC-MALS. The molecular weight determined by SEC-MALS corresponds to a monomer of DUSP26-N (C152S).
Sang-Ok Lee (2684209)   +7 more
core   +1 more source

Stage‐Specific H3K14 and H3K23 Succinylation Orchestrates Insect Metamorphosis and Oogenesis

open access: yesAdvanced Science, EarlyView.
Stage‐specific succinylation of histone H3 at lysine 14 and 23 differentially controls insect metamorphosis and oogenesis through distinct GPCR‐PKC signaling cascades, revealing an evolutionarily conserved epigenetic mechanism that coordinates key life‐history traits.
Yu‐Pu Jing   +9 more
wiley   +1 more source

Neuroprotection, Recovery of Function and Endogenous Neurogenesis in Traumatic Spinal Cord Injury Following Transplantation of Activated Adipose Tissue

open access: yesCells, 2019
Spinal cord injury (SCI) is a devastating disease, which leads to paralysis and is associated to substantially high costs for the individual and society. At present, no effective therapies are available.
Stephana Carelli   +7 more
doaj   +1 more source

Determination of particle number concentration for biological particles using AF4-MALS: Dependencies on light scattering model and refractive index

open access: yes
Determining accurate counts and size distributions for biological particles (bioparticles) is crucial in wide-ranging fields, but current ensemble methods to this end are susceptible to bias from polydispersity in size.
S. Kim Ratanathanawongs, Wiliams   +5 more
core   +1 more source

An Embodied Paper‐Based Microfluidic Al‐Air Battery for Enduring Untethered Insect‐Scale Robots

open access: yesAdvanced Science, EarlyView.
This work presents a centimeter‐scale microfluidic aluminum–air battery (MFAAB) with dual‐surface anode and F−‐mediated byproduct decomposition. The design enables a high capacity of 2697.05 mAh/g Al and delivers tens of milliwatts to power LEDs, motors, and a toy car.
Yun Yang   +5 more
wiley   +1 more source

Median arcuate ligament syndrome: a cost analysis to determine the economic burden of a rarely diagnosed disease

open access: yesFrontiers in Psychology
BackgroundChronic abdominal pain (CAP) is a medical condition resulting in enormous economic burden and healthcare utilization costs. One understudied source of CAP is the median arcuate ligament syndrome (MALS).
Christopher L. Skelly   +7 more
doaj   +1 more source

NIR‐II‐Trackable LYTACs Phyto‐Nanotheranostics for Source‐Microenvironment Dual‐Track ROS Regulation in Acute Gouty Arthritis

open access: yesAdvanced Science, EarlyView.
The TPR‐LYTACs nanomaterial offers a dual‐pathway strategy for precise gouty arthritis treatment by targeting and degrading the ROS‐producing enzyme NOX2 inside macrophages while its antioxidant core clears accumulated ROS outside. This “source inhibition and microenvironment scavenging” approach, guided by NIR‐II imaging, effectively controls local ...
Jian Zhang   +15 more
wiley   +1 more source

Intramolecular Interactions between Folded and Disordered Regions Shape Ubiquilin Structure and Function

open access: yesAdvanced Science, EarlyView.
Ubiquilin (UBQLN), like many other human proteins, contains both well‐folded and disordered regions. Here, we show that intramolecular interactions between disordered regions and folded domains modulate between open and closed topologies of UBQLN proteins, altering their structure and function.
Jessica K. Niblo   +4 more
wiley   +1 more source

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