Results 81 to 90 of about 34,836 (260)

Ortholog of autism candidate gene RBM27 regulates mitoribosomal assembly factor MALS-1 to protect against mitochondrial dysfunction and axon degeneration during neurodevelopment.

PLoS Biology
Mitochondrial dysfunction is thought to be a key component of neurodevelopmental disorders such as autism, intellectual disability, and attention-deficit hyperactivity disorder (ADHD).
Tamjid A Chowdhury, David A Luy, Garrett Scapellato, Dorian Farache, Amy S Y Lee, Christopher C Quinn   +5 more
doaj   +1 more source

Glutaredoxine reduzieren schnell Glutathionhydroper‐ und Glutathionpolysulfide

Angewandte Chemie, EarlyView.
Glutaredoxine (Grx) reduzieren Glutathionpolysulfide (GSSnSG) schnell zu Glutathionhydroper/polysulfiden (GSSnH) oder GSSnH zu Wasserstoff(poly)sulfiden (H2Sn). Die Reduktion glutathionylierter Grx durch reduziertes Glutathion (GSH) liefert Glutathiondisulfid (GSSG).
Philipp Reinert, Seiryo Ogata, Laura Leiskau, Sernur Sena Yildiz, Takaaki Akaike, Uladzimir Barayeu, Marcel Deponte   +6 more
wiley   +1 more source

Aktivierung von Metallkomplexen durch Ultraschallwellen für eine gezielte Krebstherapie

Angewandte Chemie, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source

Komplementäre Eigen–Zundel‐Interpretation bringt die Thermodynamik und Spektroskopie von Überschussprotonen in Flusssäure in Einklang

Angewandte Chemie, EarlyView.
HF‐ und HCl‐Lösungen zeigen sehr unterschiedliches Dissoziationsverhalten, weisen jedoch nahezu identische Überschussprotonenspektren auf. Dieser Widerspruch wird durch ein komplementäres Eigen–Zundel Bild aufgelöst. ZUSAMMENFASSUNG Wässrige Lösungen von HF und HCl verhalten sich bei mittleren Konzentrationen sehr unterschiedlich: HCl dissoziiert ...
Louis Lehmann, Florian N. Brünig, Jonathan Scherlitzki, Morten Lehmann, Martin Kaupp, Beate Paulus, Roland R. Netz   +6 more
wiley   +1 more source

Die Schwelle überschreiten: Kontrolle supramolekularer Polymerisation durch photostationäre Zustände

Angewandte Chemie, EarlyView.
Intermediäre photostationäre Zustände regulieren die Konzentration eines polymerisationsaktiven Monomers. Sobald die Keimbildungsschwelle überschritten wird, werden geringfügige wellenlängenabhängige Änderungen der Isomerenverteilung zu einer nichtlinearen supramolekularen Assemblierungsantwort verstärkt.
Deepu George, Jiarong Wu, Leo Greb, Vladimir Stepanenko, Aidan Izuagbe, Lutz Nuhn, Frank Würthner, Jake L. Greenfield   +7 more
wiley   +1 more source

Pelvic morphology and body size in relation to the preauricular sulcus: Evidence from medieval to modern Iberia

The Anatomical Record, EarlyView.
Abstract The preauricular sulcus has long been debated as a pelvic feature variably attributed to obstetric stress, ligamentous traction, and broader biomechanical processes. To clarify its determinants, we analyzed 409 adult individuals from three archeological and one early modern skeletal collection from the Iberian Peninsula, integrating graded ...
Rebeca García‐González, Julia Muñoz‐Guarinos, Nico Cirotto, Sonia Díaz‐Navarro, Laura Rodríguez, José Miguel Carretero   +5 more
wiley   +1 more source

Supradiaphragmatic origin of the celiac trunk leading to median arcuate ligament syndrome with superior mesenteric artery involvement

Journal of Vascular Surgery Cases and Innovative Techniques
Median arcuate ligament (MAL) syndrome (MALS) is a rare condition caused by compression of the celiac artery by the MAL. Symptoms include abdominal pain, nausea, and weight loss.
Martina Rama, BS, Wissam Nasser, MD, Prashanth Palvannan, MD, Sara Belko, MS, Paul DiMuzio, MD, FACS, Francesco Palazzo, MD, FACS   +5 more
doaj   +1 more source

Paleopathology of a putative colossosaurian caudal vertebra (Neosauropoda: Titanosauria) from the Presidente Prudente Formation, Brazil

The Anatomical Record, EarlyView.
Abstract Studies investigating paleopathologies in sauropods remain scarce despite their relative abundance in the fossil record. In this study we report new occurrence of paleopathological features, corresponding to a neoplasm found in a middle caudal vertebra (MCT.R.2120) of an advanced titanosaur from the Presidente Prudente Formation (Bauru Basin ...
Maria Luiza Peres Bertolossi, Kamila L. N. Bandeira, Roberta Veronese do Amaral, Arthur S. Brum, Rafael C. da Silva, Valéria Gallo   +5 more
wiley   +1 more source

Laparoscopic Management of Median Arcuate Ligament Syndrome in an Adolescent Girl

Journal of Indian Association of Pediatric Surgeons
This case report highlights successful laparoscopic decompression of median arcuate ligament syndrome (MALS) in a 13-year-old girl, demonstrating the effectiveness of the minimally invasive approach in resolving vascular compression.
Edamakanti Swetha Soni, T. K. Jayakumar, Harshal Madavi, Nilesh Nagdeve, Amitkumar Jadhav, Kiran Khedkar, Ketki Kedar, Siddhi Chawla   +7 more
doaj   +1 more source

Extracellular Vesicles‐Based Biological Macromolecule Delivery Systems: Biogenesis, Characterization, and Emerging Clinical Applications

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound structures that play a pivotal role in intercellular communication by transporting bioactive molecules, including proteins, lipids, nucleic acids, and organelles, between cells. Originating from the endosomal pathway, EVs reflect the physiological and pathological status of their parent
Emine İncilay Torunoğlu, Zeynep Betül Sarı, Muhammed Emin Sarı, Erdi Can Aytar   +3 more
wiley   +1 more source