Results 191 to 200 of about 132,802 (302)

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, Volume 16, Issue 3, Page 461-473, March 2026.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Disaccharidase Inhibitory Activity of Thai Plant Extracts. [PDF]

open access: yesNutrients
Kawami M   +6 more
europepmc   +1 more source

Geometrically‐Screened, Sterically‐Hindered Additive for Wide‐Temperature Aqueous Zinc‐Ion Batteries

open access: yesAdvanced Functional Materials, Volume 36, Issue 19, 5 March 2026.
A molecular‑engineering strategy combining steric hindrance tuning with geometric optimization identifies cellobiose as an ideal additive for aqueous zinc‑ion batteries, enabling stable Zn deposition across a wide temperature range from −30 to 50 °C. Abstract Aqueous zinc‐ion batteries (AZIBs) are emerging as a highly promising alternative to lithium ...
Sida Zhang   +13 more
wiley   +1 more source

Mammalian Proteome Profiling Reveals Readers and Antireaders of Strand‐Symmetric and ‐Asymmetric 5‐Hydroxymethylcytosine‐Modifications in DNA

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
We investigate by proteomics studies how strand‐symmetric and ‐asymmetric cytosine 5‐modifications in DNA are selectively recognized by the nuclear proteome. Using promoter probes with defined modification patterns, we identify tissue‐specific reader proteinsincluding MYC, MAX, and RFX5that discriminate 5‐hydroxymethylcytosine symmetry and sequence ...
Lena Engelhard   +8 more
wiley   +1 more source

Synthesis of Some Novel Chalcone and 3,5‐Disubstituted Pyrazoline Derivatives: Evaluation of Their α‐Amylase and α‐Glucosidase Inhibitory Activities In Vitro and In Silico

open access: yesArchiv der Pharmazie, Volume 359, Issue 3, March 2026.
A novel pyrazoline derivative (P2) was synthesized and demonstrated potent α‐glucosidase inhibition (IC50 = 2.10 µM), significantly surpassing acarbose and highlighting its promise as an effective oral antidiabetic agent. ABSTRACT This study reports the synthesis of some novel chalcone (C1–C3) and 3,5‐disubstituted pyrazoline derivatives (P1–P3 ...
Fatma Erbay   +6 more
wiley   +1 more source

Stabilization versus flexibility: Detergent-dependent trade-offs in neurotensin receptor 1 GPCR ensembles. [PDF]

open access: yesProtein Sci
Bower JB   +6 more
europepmc   +1 more source

Successful Management of Candida auris Bloodstream Infection in an Elderly Patient: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Candida auris is an emerging multidrug‐resistant pathogen frequently misidentified by conventional methods, posing diagnostic and infection‐control challenges, particularly in low‐ and middle‐income countries. We report a 74‐year‐old male in Dhaka, Bangladesh, with multiple comorbidities who developed Candidemia.
Arif Hasan Chowdhury   +8 more
wiley   +1 more source

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