Results 21 to 30 of about 14,055 (248)

Estado del arte el diagnóstico y tratamiento del cáncer de mama

Revista Médica Clínica Las Condes, 2013
El cáncer de mama es una enfermedad heterogénea que incluye una amplia gama de manifestaciones clínicas, radiológicas y patológicas. El proceso de diagnóstico y de tratamiento de mujeres portadoras de cáncer de mama es en esencia, multidisciplinario.
C. Soledad Torres, Dra., Dr. B. Juan Carlos Acevedo, D. Bernardita Aguirre, Dra., M. Nuvia Aliaga, Dra., Dr. G. Luis Cereceda, Dr. U. Bruno Dagnino, Dr. C. Jorge Gutiérrez, Dr. V. Álvaro Ibarra, Dr. F. Hernando Paredes, Dr. Reyes V. José Miguel, Dr. M. Verónica Robert, Dr. V. Antonio Sola, Dr. J. Ricardo Schwartz   +12 more
doaj   +1 more source

Manifestaciones radiológicas del carcinoma ductal in situ. ¿Cómo lo diagnosticamos?

Anales de Radiología, México, 2023
Objetivo: Identificar los hallazgos radiológicos en sus diferentes modalidades de imagen del carcinoma ductal in situ (CDIS) de la mama. Material y métodos: Se hizo una búsqueda de información en PubMed con las palabras “breast” AND “ductal carcinoma in ...
Jacobo E. Domínguez-García, Kictzia Y. Larios-Cruz, Nora I. Moguel-Molina, Raquel Balbás-Lara, Eva Ruvalcaba-Limón, Jorge E. Monges-Jones, Rosaura Fuentes-Corona   +6 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Використання Байєсових мереж для оцінювання точності результатів моделювання поширення домішок у повітрі за умови неточних вхідних даних

Sistemnì Doslìdženâ ta Informacìjnì Tehnologìï, 2020
Розглянуто питання оцінювання точності результатів моделювання поширення домішок у повітрі в разі подання на вхід моделей неточних вхідних даних. Наведено обмеження на методи оцінювання точності для України.
Regina V. Kryvakovska
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

HEMOSIDEROZĂ PULMONARĂ IDIOPATICĂ. UN CAZ CU BOALĂ AUTOIMUNĂ ÎN FAMILIE [PDF]

Romanian Journal of Pediatrics, 2018
Hemosideroza pulmonară idiopatică (HPI) este o boală cronică, caracterizată prin hemoragii pulmonare recurente ce afectează mai ales copiii şi are un prognostic frecvent, sever.
Cătălina Bică, Ligia Georgeta Stănescu, Liana Cismaru, Radu Diaconu, Larisa Troi, Sorin Dinescu   +5 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Impact of a Caregiver Collective

Journal of Comparative Social Work
Background. Caregivers of children with disabilities in Tanzania often face poverty, social exclusion, and mental health problems, which are compounded by stigma and limited formal support. In response, the Uhuru Mama Collective (UMC) was established in
Solfrid Raknes, Carolyne Yamala, Faudhia Kitenge, Brittany Schuler, Mariana Makuu   +4 more
doaj   +1 more source