Results 41 to 50 of about 14,055 (248)
Advanced Science, EarlyView.Photonic time crystals (PTCs) are systems in which electromagnetic parameters are modulated periodically in time, producing momentum bandgaps via temporal scattering rather than spatial Bragg processes. This review examines the theoretical frameworks, modeling, and computational tools for time‐varying media, and summarizes experimental demonstrations ...
Ranjan Kumar Patel +3 more
wiley +1 more source
Advanced Science, EarlyView.Mechanical stress activates BAP31 in chondrocytes. BAP31 competes with ATG14 for binding to STX17, disrupting the STX17–ATG14 complex required for autophagosome–lysosome fusion. The resultant autophagic flux blockade drives the generation of autophagy‐derived exosomes, which mediate pathological cartilage calcification in OA. Chondrocyte‐targeted BAP31
Zhi‐hua Xu +13 more
wiley +1 more source
Advanced Science, EarlyView.Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li +8 more
wiley +1 more source
Psicooncologia, 2019 Antecedentes: Aunque la reconstrucción mamaria (RM) tras la mastectomía es una opción estética con buenos resultados, se realiza poco en México. Para estudiar sus razones se creó el Cuestionario de Motivos a favor y en contra de la Reconstrucción Mamaria
José Moral de la Rubia +3 more
doaj +1 more source
Advanced Science, EarlyView.Aberrant GALNT7‐mediated O‐GalNAcylation stabilizes TAZ to drive gallbladder cancer progression through a feed‐forward transcriptional loop. Structure‐based screening identifies Olaparib as a potent GALNT7 antagonist that disrupts this oncogenic axis, providing an immediate therapeutic strategy for this aggressive malignancy.
Peng Qiu +11 more
wiley +1 more source
Analgesia postoperatoria con protocolo ERAS® en mastectomÃa total. Ensayo clÃnico aleatorizado
Gaceta Mexicana de OncologíaAntecedentes: Hasta un 60% de las pacientes sometidas a mastectomía por cáncer de mama presentan dolor postoperatorio grave. El protocolo Enhaced Recovery after Surgery (ERAS®) ha demostrado su utilidad para el control del dolor postoperatorio. Objetivo:
Arturo P. Miranda-Aguirre +13 more
doaj +1 more source
Advanced Science, EarlyView.A mitochondria‐targeted, microenvironment‐responsive nanoplatform enables pH/ROS‐triggered co‐delivery of berberine and isoliensinine to orchestrate ROS scavenging, inflammation suppression, and apoptosis inhibition. This vertical modulation of mitochondrial pathological networks preserves mitochondrial function and effectively mitigates myocardial ...
Jue Wang +11 more
wiley +1 more source
Advanced Science, EarlyView.This study established a high‐quality organoid biobank derived from 68 tumor sites across 50 Chinese patients, elucidated the drug sensitivity‐based molecular subtyping in breast cancer, and revealed a novel mechanism of drug resistance mediated by the FAK‐ACSL1 pathway.
Hao Xu +10 more
wiley +1 more source
JCO Global OncologyPURPOSEAdjuvant endocrine therapy (ET) improves the prognosis of patients with nonmetastatic estrogen receptor–positive (ER+) breast carcinoma; however, adherence is crucial to ensure its efficacy.
Daniele Assad-Suzuki +19 more
doaj +1 more source