Results 41 to 50 of about 54,137 (281)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Pruebas diagnósticas: Fundamentos de los estudios diagnósticos, evaluación de la validez e interpretación clínica de sus resultados

Revista Colombiana de Cirugía, 2021
El propósito de esta publicación es la de describir los fundamentos de los estudios diagnósticos, la de proporcionar elementos de juicio para valorar la validez, puntualizar sobre las medidas de utilidad o rendimiento de las mismas y resaltar la ...
Eduardo de Jesus Torregroza-Diazgranados
doaj   +1 more source

Câncer de mama em mulheres com idade igual ou superior a 65 anos: estudo de probabilidade de sobrevida livre de doença [PDF]

, 2006
Dissertação (mestrado) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Programa de Pós-Graduação em Ciências Médicas.O câncer de mama é a principal neoplasia malígna que acomete as mulheres e cerca de 50% dos casos ocorrem a partir
Traebert, Érica Elaine
core  

Temporal Trends and Short‐ and Long‐Term Mortality of People With Acute Myocardial Infarction and Rheumatoid Arthritis: A Nationwide Cohort Study

Arthritis Care &Research, EarlyView.
Objective We investigated whether a diagnosis of rheumatoid arthritis (RA) affects the quality of inpatient acute myocardial infarction (AMI) care and long‐term mortality post‐AMI. Methods We analyzed data from 784,091 adults, 6,047 with a diagnosis of RA, from England and Wales hospitalized with AMI between 2005 and 2019 from the Myocardial Ischaemia ...
Megan Butler, Nicholas Weight, Muhammad Rashid, Rodrigo Bagur, Purvi Parwani, Samantha Hider, Edward Roddy, Robert Butler, Mamas A. Mamas   +8 more
wiley   +1 more source

Field trial investigating the efficacy of a long-acting imidacloprid 10%/flumethrin 4.5% polymer matrix collar (Seresto®, Elanco) compared to monthly topical fipronil for the chemoprevention of canine tick-borne pathogens in Cambodia

Current Research in Parasitology and Vector-Borne Diseases, 2022
The tropical brown dog tick, Rhipicephalus linnaei, commonly infests canines in the tropics and is an important vector for disease-causing and sometimes lethal pathogens including Babesia spp., Ehrlichia canis, Hepatozoon canis and Anaplasma platys.
Lucas G. Huggins, Mark Stevenson, Zahida Baydoun, Ron Mab, Yulia Khouri, Bettina Schunack, Rebecca J. Traub   +6 more
doaj   +1 more source

Diagnóstico do câncer de mama auxiliado por computador :: um protótipo para detecção de microcalcificações / [PDF]

, 1999
Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico.Este trabalho apresenta o resultado das atividades realizadas no âmbito do Projeto Cyclops, no ano de 1999, sobre o diagnóstico precoce do câncer de mama auxiliado por ...
Santos, Gilmário Barbosa dos
core  

A Molecular Shielding Strategy to Develop Low Protein Binding, Renal Clearable Pan‐Cancer Near‐Infrared Probes

Advanced Functional Materials, EarlyView.
A molecular shielding strategy to convert “protein‐sticky” and “non‐tumor specific” clinical ICG dye, into a “low protein binding” and “tumor‐targeting” dye with prolonged blood circulation and renal clearance is described. These shielded ICGs demonstrate strong tumor accumulation and optimal tissue clearance, resulting in high tumor‐to‐background ...
Li Xiang, Kailin Mooney, Mingchong Dai, Morgan R. Stewart, Samantha Holland, Michael I. Henderson, Samuel Drennan, Ramon F. Barajas Jr., Jared M. Fischer, Adem Yildirim   +9 more
wiley   +1 more source

Dose dense versus 3 weekly AC during neoadjuvant chemoimmunotherapy for triple negative breast cancer

npj Breast Cancer
Neoadjuvant pembrolizumab plus chemotherapy (P + CT) has emerged as a standard of care for stage II-III triple-negative breast cancer (TNBC). However, the best anthracycline-cyclophosphamide (AC) schedule remains to be determined.
Renata Colombo Bonadio, Isadora Martins de Sousa, Flávia Cavalcanti Balint, Ana Carolina Marin Comini, Monique Celeste Tavares, Fernanda Madasi, Jose Bines, Rafael Dal Ponte Ferreira, Daniela Dornelles Rosa, Candice Lima Santos, Zenaide Silva de Souza, Daniele Assad-Suzuki, Júlio Antônio Pereira de Araújo, Débora de Melo Gagliato, Carlos Henrique dos Anjos, Bruna M. Zucchetti, Anezka Ferrari, Mayana Lopes de Brito, Renata Cangussu, Maria Marcela Fernandes Monteiro, Paulo M. Hoff, Laura Testa, Romualdo Barroso-Sousa   +22 more
doaj   +1 more source

Rotura de implante mamario: hallazgos en imágenes

Revista Médica Clínica Las Condes, 2010
Se describe un caso de rotura intracapsular de implante en una paciente asintomática y su estudio diagnóstico con imágenes, analizándose el aporte de cada uno de los métodos incluyendo mamografía, ecografía y resonancia magnética, para el estudio de ...
V. Paulina Neira, Dra., D. Bernardita Aguirre, Dra.   +1 more
doaj   +1 more source