Results 31 to 40 of about 377,358 (296)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

There\u27s Nobody Home But Me [PDF]

, 1918
[Verse 2]A garden gate, a lad of eight, Dressed in a uniform of brown, Across the way, a troop that day Were getting volunteers in town “Who’s home with you, my boy?” they cried, The child saluted and replied: [Chorus] My brother’s over in the trenches ...
Conrad, Con, Ehrlich, Sam
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Field trial investigating the efficacy of a long-acting imidacloprid 10%/flumethrin 4.5% polymer matrix collar (Seresto®, Elanco) compared to monthly topical fipronil for the chemoprevention of canine tick-borne pathogens in Cambodia

Current Research in Parasitology and Vector-Borne Diseases, 2022
The tropical brown dog tick, Rhipicephalus linnaei, commonly infests canines in the tropics and is an important vector for disease-causing and sometimes lethal pathogens including Babesia spp., Ehrlichia canis, Hepatozoon canis and Anaplasma platys.
Lucas G. Huggins, Mark Stevenson, Zahida Baydoun, Ron Mab, Yulia Khouri, Bettina Schunack, Rebecca J. Traub   +6 more
doaj   +1 more source

Dear Mama [PDF]

, 2019
Third of ten poems written by the late and great Nigerian Poet Ikeogu ...
Oke, Ikeogu
core   +1 more source

Restructuring and Rebranding: The Need for Another Revolution in the Loire [PDF]

, 2008
International ...
E. Simon, J.C. Taddei, P.R. Gamble
core   +2 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Pruebas diagnósticas: Fundamentos de los estudios diagnósticos, evaluación de la validez e interpretación clínica de sus resultados

Revista Colombiana de Cirugía, 2021
El propósito de esta publicación es la de describir los fundamentos de los estudios diagnósticos, la de proporcionar elementos de juicio para valorar la validez, puntualizar sobre las medidas de utilidad o rendimiento de las mismas y resaltar la ...
Eduardo de Jesus Torregroza-Diazgranados
doaj   +1 more source

Drawing Mama, a Practical Drawing Tutorial Book for Parents [PDF]

, 2019
Parents need to be closer to their children, especially when they are in early years. The process of the approach can be done in some creative way, one example is drawing together with children.
Azhar, D. A. (Devi ), Rahman, Y. (Yanuar )   +1 more
core  

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source