Results 101 to 110 of about 770,892 (320)

Salient features in locomotor evolutionary adaptations of proboscideans revealed via the differential scaling of limb long bones [PDF]

arXiv, 2009
The standard differential scaling of proportions in limb long bones (length against circumference) is applied to a phylogenetically wide sample of the Proboscidea, Elephantidae and the Asian (Elephas maximus) and African elephant (Loxodonta africana). In order to investigate allometric patterns in proboscideans and terrestrial mammals with parasagittal
arxiv  

The Status of the World's Land and Marine Mammals: Diversity, Threat, and Knowledge

Science, 2008
Knowledge of mammalian diversity is still surprisingly disparate, both regionally and taxonomically. Here, we present a comprehensive assessment of the conservation status and distribution of the world's mammals.
J. Schipper, J. Chanson, Federica Chiozza, N. Cox, M. Hoffmann, Vineet Katariya, John F. Lamoreux, A. Rodrigues, S. Stuart, H. Temple, J. Baillie, L. Boitani, T. Lacher, R. Mittermeier, Andrew T. Smith, Daniel Absolon, John M. Aguiar, G. Amori, Noura Bakkour, R. Baldi, R. Berridge, J. Bielby, P. Black, J. Blanc, T. Brooks, J. Burton, T. Butynski, G. Catullo, R. Chapman, Zoe Cokeliss, B. Collen, J. Conroy, J. Cooke, G. A. D. da Fonseca, A. Derocher, H. Dublin, J. Duckworth, L. Emmons, R. Emslie, M. Festa‐Bianchet, Matt Foster, S. Foster, D. Garshelis, C. Gates, Mariano Gimenez-Dixon, S. González, José F. González-Maya, T. Good, G. Hammerson, P. Hammond, D. Happold, M. Happold, J. Hare, R. Harris, C. Hawkins, M. Haywood, L. Heaney, S. Hedges, K. Helgen, C. Hilton‐Taylor, S. A. Hussain, N. Ishii, T. Jefferson, Richard K. B. Jenkins, Charlotte H. Johnston, M. Keith, J. Kingdon, D. Knox, K. Kovacs, P. Langhammer, K. Leus, R. Lewison, G. Lichtenstein, L. Lowry, Zoe Macavoy, G. Mace, David P. Mallon, M. Masi, Meghan W. McKnight, R. Medellín, P. Medici, Gus Mills, P. Moehlman, S. Molur, Arturo Mora, K. Nowell, J. Oates, W. Olech, W. Oliver, M. Oprea, Bruce D. Patterson, W. Perrin, B. Polidoro, C. Pollock, A. Powel, Y. Protas, P. Racey, J. Ragle, P. Ramani, G. Rathbun, R. Reeves, S. Reilly, J. Reynolds, C. Rondinini, R. G. Rosell-Ambal, M. Rulli, A. Rylands, S. Savini, C. Schank, W. Sechrest, C. Self-Sullivan, A. Shoemaker, C. Sillero-Zubiri, N. De Silva, David E. Smith, C. Srinivasulu, P. Stephenson, Nico van Strien, B. Talukdar, B. Taylor, R. Timmins, Diego G. Tirira, M. Tognelli, Katerina Tsytsulina, Liza M. Veiga, J. Vié, E. Williamson, Sarah A. Wyatt, Yan Xie, B. Young   +129 more
semanticscholar   +1 more source

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

FEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu, Yabin Wu, Chunye Zhao, Jie Zheng, Shangwu Chen, Yigang Wang, Yulong Xia   +6 more
wiley   +1 more source

Innate humoral immune defences in mammals and insects: The same, with differences ?

Virulence, 2018
The insect immune response demonstrates many similarities to the innate immune response of mammals and a wide range of insects is now employed to assess the virulence of pathogens and produce results comparable to those obtained using mammals.
G. Sheehan, Amy Garvey, Michael Croke, K. Kavanagh   +3 more
semanticscholar   +1 more source

Calcium modulating ligand confers risk for Parkinson's disease and impacts lysosomes

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Objective Several genetic loci known to confer risk for Parkinson's disease (PD) function in lysosomal pathways. We systematically screened common variants linked to PD risk by genome‐wide association studies (GWAS) for impact on cerebrospinal fluid (CSF) proteins reflecting lysosomal function.
Hanwen Zhang, Daniel Kargilis, Thomas Tropea, John Robinson, Junchao Shen, Eliza M. Brody, Ann Brinkmalm, Simon Sjödin, Adama J. Berndt, Marc Carceles‐Cordon, EunRan Suh, Vivianna M. Van Deerlin, Kaj Blennow, Daniel Weintraub, Edward B. Lee, Henrik Zetterberg, Alice S. Chen‐Plotkin   +16 more
wiley   +1 more source

Hierarchy in Structuring of Resource Selection: Understanding Elk Selection Across Space, Time, and Movement Strategies

Ecology and Evolution
Movement is a fundamental aspect of animal ecology that varies across space, time, and among individuals or groups within a population. Broad‐scale patterns of animal movement are often classified into different movement strategies, such as resident ...
Storm Crews, Nathaniel D. Rayl, Mathew W. Alldredge, Eric J. Bergman, Chuck R. Anderson Jr., Eric H. VanNatta, Joseph D. Holbrook, Guillaume Bastille‐Rousseau   +7 more
doaj   +1 more source

Amygdala Neurodegeneration: A Key Driver of Visual Dysfunction in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Visual disability in Parkinson's disease (PD) is not fully explained by retinal neurodegeneration. We aimed to delineate the brain substrate of visual dysfunction in PD and its association with retinal thickness. Methods Forty‐two PD patients and 29 controls underwent 3‐Tesla MRI, retinal spectral‐domain optical coherence tomography,
Asier Erramuzpe, Ane Murueta‐Goyena, Antonio Jimenez‐Marin, Marian Acera, Sara Teijeira‐Portas, Rocío Del Pino, Tamara Fernández‐Valle, Ibai Diez, Unai Sainz‐Lugarezaresti, Naroa Ibarretxe‐Bilbao, Unai Ayala, Maitane Barrenechea, Alberto Cabrera‐Zubizarreta, Jesús Cortés, Juan Carlos Gómez‐Esteban, Iñigo Gabilondo   +15 more
wiley   +1 more source

Abnormal Synchronization Between Cortical Delta Power and Ripples in Hippocampal Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Discriminating between epileptogenic and physiological ripples in the hippocampus is important for identifying epileptogenic (EP) zones; however, distinguishing these ripples on the basis of their waveforms is difficult. We hypothesized that the nocturnal synchronization of hippocampal ripples and cortical delta power could be used ...
Takamitsu Iwata, Takufumi Yanagisawa, Ryohei Fukuma, Yuji Ikegaya, Satoru Oshino, Naoki Tani, Hui Ming Khoo, Hidenori Sugano, Yasushi Iimura, Hiroharu Suzuki, Haruhiko Kishima   +10 more
wiley   +1 more source

Lineage-specific transposons drove massive gene expression recruitments during the evolution of pregnancy in mammals [PDF]

arXiv, 2012
A major challenge in biology is explaining how novel characters originate, however, the molecular mechanisms that underlie the emergence of evolutionary innovations are unclear. Here we show that while gene expression in the uterus evolves at a slow and relatively constant rate, it has been punctuated by periods of rapid change associated with the ...
arxiv  

DNA methylation in mammals.

Cold Spring Harbor Perspectives in Biology, 2014
DNA methylation is one of the best characterized epigenetic modifications. In mammals it is involved in various biological processes including the silencing of transposable elements, regulation of gene expression, genomic imprinting, and X-chromosome ...
E. Li, Yi Zhang
semanticscholar   +1 more source